1. A nucleus-encoded chloroplast protein regulated by iron availability governs expression of the photosystem I subunit PsaA in Chlamydomonas reinhardtii.

    Plant Physiology 167(4):1527 (2015) PMID 25673777 PMCID PMC4378161

    The biogenesis of the photosynthetic electron transfer chain in the thylakoid membranes requires the concerted expression of genes in the chloroplast and the nucleus. Chloroplast gene expression is subjected to anterograde control by a battery of nucleus-encoded proteins that are imported in the...
  2. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology 25(6):817 (2015)

  3. Uninflatable and Notch control the targeting of sara endosomes during asymmetric division.

    Current Biology 24(18):2142 (2014) PMID 25155514

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1-6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with its distinct...
  4. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology 24(18):2142 (2014)

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1–6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with it...
  5. Uninflatable and Notch control the targeting of Sara endosomes during asymmetric division.

    Current Biology 24(18):2142 (2014) PMID 25155514

    Cell fate decision during asymmetric division is mediated by the biased partition of cell fate determinants during mitosis [1-6]. In the case of the asymmetric division of the fly sensory organ precursor cells, directed Notch signaling from pIIb to the pIIa daughter endows pIIa with its distinct...
  6. A pathway for repair of NAD(P)H in plants.

    Journal of Biological Chemistry 289(21):14692 (2014) PMID 24706747 PMCID PMC4031525

    Unwanted enzyme side reactions and spontaneous decomposition of metabolites can lead to a build-up of compounds that compete with natural enzyme substrates and must be dealt with for efficient metabolism. It has recently been realized that there are enzymes that process such compounds, formulati...
  7. A pathway for repair of NAD(P)H in plants.

    Journal of Biological Chemistry 289(21):14692 (2014) PMID 24706747 PMCID PMC4031525

    Unwanted enzyme side reactions and spontaneous decomposition of metabolites can lead to a build-up of compounds that compete with natural enzyme substrates and must be dealt with for efficient metabolism. It has recently been realized that there are enzymes that process such compounds, formulati...
  8. Monitoring notch/delta endosomal trafficking and signaling in Drosophila.

    Methods in Enzymology 534:301 (2014) PMID 24359961

    The Notch signaling pathway plays important roles in many organisms and developmental contexts. The activities of the Notch receptor and of its ligand Delta are known to be regulated at several steps along the endocytic pathway. However, the precise molecular mechanism of Notch activation and th...
  9. Monitoring notch/delta endosomal trafficking and signaling in Drosophila.

    Methods in Enzymology 534:301 (2014) PMID 24359961

    The Notch signaling pathway plays important roles in many organisms and developmental contexts. The activities of the Notch receptor and of its ligand Delta are known to be regulated at several steps along the endocytic pathway. However, the precise molecular mechanism of Notch activation and th...
  10. Myosin VI regulates actin dynamics and melanosome biogenesis.

    Traffic 13(5):665 (2012) PMID 22321127

    Myosin VI has been implicated in various steps of organelle dynamics. However, the molecular mechanism by which this myosin contributes to membrane traffic is poorly understood. Here, we report that myosin VI is associated with a lysosome-related organelle, the melanosome. Using an actin-based m...
  11. Myosin VI regulates actin dynamics and melanosome biogenesis.

    Traffic 13(5):665 (2012) PMID 22321127

    Myosin VI has been implicated in various steps of organelle dynamics. However, the molecular mechanism by which this myosin contributes to membrane traffic is poorly understood. Here, we report that myosin VI is associated with a lysosome-related organelle, the melanosome. Using an actin-based m...
  12. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology (2012)

  13. ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis.

    Current Biology 19(3):184 (2009) PMID 19211056

    Recent work has highlighted the importance of the recycling of endocytic membranes to the intercellular bridge for completion of cytokinesis in animal cells. ADP-ribosylation factor 6 (ARF6), which localizes to the plasma membrane and endosomal compartments, regulates endocytic recycling to the ...
  14. ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis.

    Current Biology 19(3):184 (2009) PMID 19211056

    Recent work has highlighted the importance of the recycling of endocytic membranes to the intercellular bridge for completion of cytokinesis in animal cells. ADP-ribosylation factor 6 (ARF6), which localizes to the plasma membrane and endosomal compartments, regulates endocytic recycling to the ...
  15. ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis.

    Current Biology 19(3):184 (2009) PMID 19211056

    Recent work has highlighted the importance of the recycling of endocytic membranes to the intercellular bridge for completion of cytokinesis in animal cells. ADP-ribosylation factor 6 (ARF6), which localizes to the plasma membrane and endosomal compartments, regulates endocytic recycling to the ...
  16. ARF6 Interacts with JIP4 to Control a Motor Switch Mechanism Regulating Endosome Traffic in Cytokinesis

    Current Biology 19(3):184 (2009)

    Background Recent work has highlighted the importance of the recycling of endocytic membranes to the intercellular bridge for completion of cytokinesis in animal cells. ADP-ribosylation factor 6 (ARF6), which localizes to the plasma membrane and endosomal compartments, regulates endocy...
  17. Different microtubule motors move early and late endocytic compartments.

    Traffic 9(4):492 (2008) PMID 18194411

    Important progress has been made during the past decade in the identification of molecular motors required in the distribution of early and late endosomes and the proper trafficking along the endocytic pathway. There is little direct evidence, however, that these motors drive movement of the end...
  18. Different microtubule motors move early and late endocytic compartments.

    Traffic 9(4):492 (2008) PMID 18194411

    Important progress has been made during the past decade in the identification of molecular motors required in the distribution of early and late endosomes and the proper trafficking along the endocytic pathway. There is little direct evidence, however, that these motors drive movement of the end...