1. Silk-based biomaterials in biomedical textiles and fiber-based implants.

    Advanced Healthcare Materials 4(8):1134 (2015) PMID 25772248 PMCID PMC4456268

    Biomedical textiles and fiber-based implants (BTFIs) have been in routine clinical use to facilitate healing for nearly five decades. Amongst the variety of biomaterials used, silk-based biomaterials (SBBs) have been widely used clinically viz. sutures for centuries and are being increasingly re...
  2. Seroepidemiology of Norovirus GII.3 and GII.4 Infections in Children with Diarrhea in Xi'an, China.

    Foodborne Pathogens and Disease 12(6):500 (2015) PMID 25789571

    The objective of this study was to investigate the seroepidemiology of immunoglobulin G (IgG) antibodies against Norovirus (NoV) GII.3 and GII.4 genotypes among children younger than 5 years with acute diarrhea in Xi'an, China. A total of 362 serum samples were collected from diarrheal children ...
  3. Behavioral dependence of auditory cortical responses.

    Brain Topography 28(3):365 (2015) PMID 25690831 PMCID PMC4409507

    Neural responses in the auditory cortex have historically been measured from either anesthetized or awake but non-behaving animals. A growing body of work has begun to focus instead on recording from auditory cortex of animals actively engaged in behavior tasks. These studies have shown that aud...
  4. Point and interval estimation of baseline risk and treatment effect based on logistic model for observational studies.

    Biometrical Journal 57(3):441 (2015) PMID 25810034

    In observational studies with dichotomous outcome of a population, researchers usually report treatment effect alone, although both baseline risk and treatment effect are needed to evaluate the significance of the treatment effect to the population. In this article, we study point and interval e...
  5. Control of silicification by genetically engineered fusion proteins: Silk-silica binding peptides.

    Acta Biomaterialia 15:173 (2015) PMID 25462851 PMCID PMC4331239

    In the present study, an artificial spider silk gene, 6mer, derived from the consensus sequence of Nephila clavipes dragline silk gene, was fused with different silica-binding peptides (SiBPs), A1, A3 and R5, to study the impact of the fusion protein sequence chemistry on silica formation and th...
  6. Control of silicification by genetically engineered fusion proteins: Silk-silica binding peptides.

    Acta Biomaterialia 15:173 (2015) PMID 25462851

    In the present study, an artificial spider silk gene, 6mer, derived from the consensus sequence of Nephila clavipes dragline silk gene, was fused with different silica-binding peptides (SiBPs), A1, A3 and R5, to study the impact of the fusion protein sequence chemistry on silica formation and th...
  7. Control of silicification by genetically engineered fusion proteins: Silk-silica binding peptides.

    Acta Biomaterialia 15:173 (2015) PMID 25462851

    In the present study, an artificial spider silk gene, 6mer, derived from the consensus sequence of Nephila clavipes dragline silk gene, was fused with different silica-binding peptides (SiBPs), A1, A3 and R5, to study the impact of the fusion protein sequence chemistry on silica formation and th...
  8. Control of silicification by genetically engineered fusion proteins: Silk-silica binding peptides.

    Acta Biomaterialia 15:173 (2015) PMID 25462851 PMCID PMC4331239

    In the present study, an artificial spider silk gene, 6mer, derived from the consensus sequence of Nephila clavipes dragline silk gene, was fused with different silica-binding peptides (SiBPs), A1, A3 and R5, to study the impact of the fusion protein sequence chemistry on silica formation and th...
  9. Injectable silk-polyethylene glycol hydrogels.

    Acta Biomaterialia 12:51 (2015) PMID 25449912

    Silk hydrogels for tissue repair are usually pre-formed via chemical or physical treatments from silk solutions. For many medical applications, it is desirable to utilize injectable silk hydrogels at high concentrations (>8%) to avoid surgical implantation and to achieve slow in vivo degradation...
  10. Injectable silk-polyethylene glycol hydrogels.

    Acta Biomaterialia 12:51 (2015) PMID 25449912

    Silk hydrogels for tissue repair are usually pre-formed via chemical or physical treatments from silk solutions. For many medical applications, it is desirable to utilize injectable silk hydrogels at high concentrations (>8%) to avoid surgical implantation and to achieve slow in vivo degradation...
  11. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.

    Acta Biomaterialia 11:222 (2015) PMID 25132274 PMCID PMC4256115

    Curcumin, a natural phenolic compound derived from the plant Curcuma longa, was physically entrapped and stabilized in silk hydrogel films, and its influence on human bone marrow-derived mesenchymal stem cells (hBMSC) was assessed related to adipogenic differentiation. The presence of curcumin s...
  12. Injectable silk-polyethylene glycol hydrogels.

    Acta Biomaterialia 12:51 (2015) PMID 25449912

    Silk hydrogels for tissue repair are usually pre-formed via chemical or physical treatments from silk solutions. For many medical applications, it is desirable to utilize injectable silk hydrogels at high concentrations (>8%) to avoid surgical implantation and to achieve slow in vivo degradation...
  13. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.

    Acta Biomaterialia 11:222 (2015) PMID 25132274 PMCID PMC4256115

    Curcumin, a natural phenolic compound derived from the plant Curcuma longa, was physically entrapped and stabilized in silk hydrogel films, and its influence on human bone marrow-derived mesenchymal stem cells (hBMSC) was assessed related to adipogenic differentiation. The presence of curcumin s...
  14. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.

    Acta Biomaterialia 11:222 (2015) PMID 25132274 PMCID PMC4256115

    Curcumin, a natural phenolic compound derived from the plant Curcuma longa, was physically entrapped and stabilized in silk hydrogel films, and its influence on human bone marrow-derived mesenchymal stem cells (hBMSC) was assessed related to adipogenic differentiation. The presence of curcumin s...
  15. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells

    Acta Biomaterialia 11:222 (2015)

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  16. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells

    Acta Biomaterialia 11:222 (2015)

    [Display omitted]
  17. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells

    Acta Biomaterialia 11:222 (2015)

    [Display omitted]
  18. A single dose of dexamethasone encapsulated in polyethylene glycol-coated polylactic acid nanoparticles attenuates cisplatin-induced hearing loss following round window membrane administration.

    International Journal of Nanomedicine 10:3567 (2015) PMID 25999718 PMCID PMC4437605

    This study aimed to investigate the sustained drug release properties and hearing protection effect of polyethylene glycol-coated polylactic acid (PEG-PLA) stealth nanoparticles loaded with dexamethasone (DEX). DEX was fabricated into PEG-PLA nanoparticles using an emulsion and evaporation techn...
  19. Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.

    Acta Biomaterialia 11:222 (2015) PMID 25132274 PMCID PMC4256115

    Curcumin, a natural phenolic compound derived from the plant Curcuma longa, was physically entrapped and stabilized in silk hydrogel films, and its influence on human bone marrow-derived mesenchymal stem cells (hBMSC) was assessed related to adipogenic differentiation. The presence of curcumin s...
  20. The emerging role of extracellular vesicles as biomarkers for urogenital cancers.

    Nature Reviews Urology 11(12):688 (2014) PMID 25403245

    The knowledge gained from comprehensive profiling projects that aim to define the complex genomic alterations present within cancers will undoubtedly improve our ability to detect and treat those diseases, but the influence of these resources on our understanding of basic cancer biology is still...