1. The role of CCL20/CCR6 axis in recruiting Treg cells to tumor sites of NSCLC patients

    Biomedicine & Pharmacotherapy 69:242 (2015)

    Inflammatory chemokine CCL20 and its receptor CCR6 have been reported to correlate with colorectal cancer patients’ metastasis. However, the role of CCL20 in patients with NSCLC is not well defined. In this study, we detected the expression of CCL20 in tumor samples and corresponding a...
  2. The role of CCL20/CCR6 axis in recruiting Treg cells to tumor sites of NSCLC patients.

    Biomedicine & Pharmacotherapy 69:242 (2015) PMID 25661365

    Inflammatory chemokine CCL20 and its receptor CCR6 have been reported to correlate with colorectal cancer patients' metastasis. However, the role of CCL20 in patients with NSCLC is not well defined. In this study, we detected the expression of CCL20 in tumor samples and corresponding adjacent on...
  3. Metallothionein isoform 3 expression in human skin, related cancers and human skin derived cell cultures

    Toxicology Letters 232(1):141 (2015)

    • Skin is a target site of As+3 toxicity. • Metallothionein-3 (MT3) is highly expressed in human skin. • ...
  4. Cadherin Expression, Vectorial Active Transport, and Metallothionein Isoform 3 Mediated EMT/MET Responses in Cultured Primary and Immortalized Human Proximal Tubule Cells.

    PLoS ONE 10(3):e0120132 (2015) PMID 25803827 PMCID PMC4372585

    Cultures of human proximal tubule cells have been widely utilized to study the role of EMT in renal disease. The goal of this study was to define the role of growth media composition on classic EMT responses, define the expression of E- and N-cadherin, and define the functional epitope of MT-3 t...
  5. Health system reform in rural China: Voices of healthworkers and service-users

    Social Science & Medicine 117:134 (2014)

    Like many other countries China is undergoing major health system reforms, with the aim of providing universal health coverage, and addressing problems of low efficiency and inequity. The first phase of the reforms has focused on strengthening primary care and improving health insuranc...
  6. Abnormal functional connectivity density in psychogenic non-epileptic seizures.

    Epilepsy Research 108(7):1184 (2014) PMID 24974125

    Psychogenic non-epileptic seizures (PNES) are paroxysmal behaviors that resemble epileptic seizures but lack abnormal electrical activity. Some neuroimaging studies have reported that PNES exhibits aberrant functional connectivity in specific brain networks. Thus, advanced neuroimaging technolog...
  7. Health system reform in rural China: voices of healthworkers and service-users.

    Social Science & Medicine 117:134 (2014) PMID 25063969

    Like many other countries China is undergoing major health system reforms, with the aim of providing universal health coverage, and addressing problems of low efficiency and inequity. The first phase of the reforms has focused on strengthening primary care and improving health insurance coverage...
  8. Sociosexuality in mainland China.

    Archives of Sexual Behavior 43(3):621 (2014) PMID 23740470

    The construct of sociosexuality or sociosexual orientation describes the extent to which people will have casual, uncommitted sexual relationships. The Sociosexual Orientation Inventory (SOI) has been used to measure sociosexuality in many countries, but not in China. The aims of this study were...
  9. Sociosexuality in mainland China.

    Archives of Sexual Behavior 43(3):621 (2014) PMID 23740470

    The construct of sociosexuality or sociosexual orientation describes the extent to which people will have casual, uncommitted sexual relationships. The Sociosexual Orientation Inventory (SOI) has been used to measure sociosexuality in many countries, but not in China. The aims of this study were...
  10. Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence.

    Age 36(4):9675 (2014) PMID 24994537 PMCID PMC4150908

    The α1-adrenergic receptor (α1AR) subtypes, α1AAR and α1BAR, have differential effects in the heart and central nervous system. Long-term stimulation of the α1AAR subtype prolongs lifespan and provides cardio- and neuro-protective effects. We examined the lifespan of constitutively active mutant...
  11. Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence.

    Age 36(4):9675 (2014) PMID 24994537 PMCID PMC4150908

    The α1-adrenergic receptor (α1AR) subtypes, α1AAR and α1BAR, have differential effects in the heart and central nervous system. Long-term stimulation of the α1AAR subtype prolongs lifespan and provides cardio- and neuro-protective effects. We examined the lifespan of constitutively active mutant...
  12. Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence.

    Age 36(4):9675 (2014) PMID 24994537 PMCID PMC4150908

    The α1-adrenergic receptor (α1AR) subtypes, α1AAR and α1BAR, have differential effects in the heart and central nervous system. Long-term stimulation of the α1AAR subtype prolongs lifespan and provides cardio- and neuro-protective effects. We examined the lifespan of constitutively active mutant...
  13. High sex ratio as a correlate of depression in Chinese men

    Journal of Affective Disorders 144(1-2):79 (2013) PMID 22840624

    Background There is a large and increasing excess of men in China, especially in poor rural areas, with millions now unable to marry. The study aimed to determine whether these high sex ratios influence the prevalence of depression.
  14. High sex ratio as a correlate of depression in Chinese men

    Journal of Affective Disorders 144(1-2):79 (2013)

    Background There is a large and increasing excess of men in China, especially in poor rural areas, with millions now unable to marry. The study aimed to determine whether these high sex ratios influence the prevalence of depression.
  15. High sex ratio as a correlate of depression in Chinese men.

    Journal of Affective Disorders 144(1-2):79 (2013) PMID 22840624

    There is a large and increasing excess of men in China, especially in poor rural areas, with millions now unable to marry. The study aimed to determine whether these high sex ratios influence the prevalence of depression. The study was a cross-sectional survey, using a self-completion questionna...
  16. Metallothionein Isoform 3 Expression in Human Skin, Related Cancers and Human Skin Derived Cell Cultures

    Toxicology Letters 232(1) (2013)

    • Skin is a target site of As+3 toxicity • Metallothionein-3 (MT3) is highly expressed in human skin • ...
  17. Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd2+or As3+

    Toxicology Letters 212(1):66 (2012)

    Highlights ► Transformation of the normal bladder cell line, UROtsa, increased the expression of enolase-2. ► Cd2+ or As3+ induced the expression of enolase-2 in non-transformed UROtsa cells. ► An HDAC inhibitor induced the expression, indicating epigenetic control mechanisms...
  18. Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd2+or As3+

    Toxicology Letters 212(1):66 (2012) PMID 22613180 PMCID PMC3390755

    Highlights ► Transformation of the normal bladder cell line, UROtsa, increased the expression of enolase-2. ► Cd2+ or As3+ induced the expression of enolase-2 in non-transformed UROtsa cells. ► An HDAC inhibitor induced the expression, indicating epigenetic control mechanisms...
  19. Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd²⁺ or As³⁺.

    Toxicology Letters 212(1):66 (2012) PMID 22613180 PMCID PMC3390755

    Neuron specific enolase (ENO2, γ-enolase) is a biomarker used to help identify neuroendocrine differentiation in tumors. This laboratory has shown that ENO2 might be a biomarker for exposure to cadmium and arsenite. In this study these observations are extended to the urothelial cell, where envi...
  20. Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd²⁺ or As³⁺.

    Toxicology Letters 212(1):66 (2012) PMID 22613180 PMCID PMC3390755

    Neuron specific enolase (ENO2, γ-enolase) is a biomarker used to help identify neuroendocrine differentiation in tumors. This laboratory has shown that ENO2 might be a biomarker for exposure to cadmium and arsenite. In this study these observations are extended to the urothelial cell, where envi...