1. Ultrasensitive photoelectrochemical aptasensing of miR-155 using efficient and stable CH3NH3PbI3 quantum dots sensitized ZnO nanosheets as light harvester.

    Biosensors and Bioelectronics 85:142 (2016) PMID 27162145

    An ultrasensitive photoelectrochemical (PEC) aptasensor based on a novel signal amplification strategy was developed for the quantitative determination of microRNA (miR)-155. CH3NH3PbI3 quantum dots (QDs) functionalized ZnO nanosheets (NSs) were employed as the light harvester. Owing to the syne...
  2. A network signal amplification strategy of ultrasensitive photoelectrochemical immunosensing carcinoembryonic antigen based on CdSe/melamine network as label.

    Biosensors and Bioelectronics 85:764 (2016) PMID 27281106

    Taking advantage of CdSe/melamine network as label and Au-TiO2 as substrate, this work developed a novel kind of signal amplification strategy for fabricating photoelectrochemical (PEC) immunoassay. The melamine, a star-shaped triamino molecule, was firstly used for readily capturing CdSe QDs an...
  3. A method linking the toxic effects at community-level with contaminant concentrations.

    Science of The Total Environment 569-570:352 (2016) PMID 27348700

    In this study, we developed a method to quantify and link the toxic effects in community-level ecosystems with concentrations of petroleum hydrocarbons. The densities of Platymonas helgolandica var. tsingtaoensis, Isochrysis galbana, and Brachionus plicatilis in single-species tests and customiz...
  4. A hybrid process combining homogeneous catalytic ozonation and membrane distillation for wastewater treatment.

    Chemosphere 160:134 (2016) PMID 27372262

    A novel catalytic ozonation membrane reactor (COMR) coupling homogeneous catalytic ozonation and direct contact membrane distillation (DCMD) was developed for refractory saline organic pollutant treatment from wastewater. An ozonation process took place in the reactor to degrade organic pollutan...
  5. Cytokine-induced killer cell therapy-associated idiopathic thrombocytopenic purpura: rare but noteworthy.

    Immunotherapy 8(9):1003 (2016) PMID 27485074

    Idiopathic thrombocytopenic purpura (ITP) is characterized by a diminished platelet count, an autoimmune condition with antibodies against platelets and an increased tendency to bleed. The association between ITP and solid tumors is uncommon. Cytokine-induced killer (CIK) cell therapy is a well ...
  6. The effectiveness and safety of amisulpride in Chinese patients with schizophrenia: An 8-week, prospective, open-label, multicenter, single-arm study.

    Asia Pacific Psychiatry 8(3):241 (2016) PMID 27020720

    This study evaluated the effectiveness and safety of amisulpride in Chinese schizophrenia patients. A multicenter, single-arm Phase IV study (NCT01795183). Chinese patients with schizophrenia received amisulpride for 8 weeks. The primary endpoint was ≥50% decrease in Positive and Negative Syndro...
  7. Exercise-induced hormesis and skeletal muscle health.

    Free Radical Biology and Medicine 98:113 (2016) PMID 26916558

    Hormesis refers to the phenomenon that an exposure or repeated exposures of a toxin can elicit adaptive changes within the organism to resist to higher doses of toxin with reduced harm. Skeletal muscle shows considerable plasticity and adaptions in response to a single bout of acute exercise or ...
  8. Sex differences in responsiveness to the prescription opioid oxycodone in mice.

    Pharmacology Biochemistry and Behavior 148:99 (2016) PMID 27316549

    Over-prescription and increased nonmedical use of oxycodone has become a major concern. Despite its increased use, preclinical data concerning oxycodone's effects are still limited, especially in rodent models. To address this, we examined oxycodone's effects on place preference, locomotor activ...
  9. Size-Controlled TiO2 nanocrystals with exposed {001} and {101} facets strongly linking to graphene oxide via p-Phenylenediamine for efficient photocatalytic degradation of fulvic acids.

    Journal of Hazardous Materials 314:41 (2016) PMID 27107234

    Photocatalytic degradation is one of the most promising methods for removal of fulvic acids (FA), which is a typical category of natural organic contamination in groundwater. In this paper, TiO2/graphene nanocomposites (N-RGO/TiO2) were prepared via simple chemical functionalization and one-step...
  10. Climate change and human activities altered the diversity and composition of soil microbial community in alpine grasslands of the Qinghai-Tibetan Plateau.

    Science of The Total Environment 562:353 (2016) PMID 27100015

    Alpine ecosystems are known to be sensitive to climate change and human disturbances. However, the knowledge about the changes of their underground microbial communities is inadequate. We explored the diversity and structure of soil bacterial and fungal communities using Ilumina MiSeq sequencing...
  11. Facile fabrication of an electrochemical aptasensor based on magnetic electrode by using streptavidin modified magnetic beads for sensitive and specific detection of Hg(2.).

    Biosensors and Bioelectronics 82:9 (2016) PMID 27031185

    In this work, a novel electrochemical aptasensor was developed for sensitive and specific detection of Hg(2+) based on thymine-Hg(2+)-thymine (T-Hg(2+)-T) structure via application of thionine (Th) as indicator signal. For the fabrication of the aptasensor, streptavidin modified magnetic beads (...
  12. Synthesis, biological evaluation and molecular docking of 2-phenyl-benzo[d]oxazole-7-carboxamide derivatives as potential Staphylococcus aureus Sortase A inhibitors.

    Bioorganic & Medicinal Chemistry Letters 26(16):4081 (2016) PMID 27400889

    A series of novel 2-phenyl-benzo[d]oxazole-7-carboxamide derivatives were designed, synthesized and evaluated for their in vitro inhibitory activities against Staphylococcus aureus Sortase A with known Sortase A inhibitor pHMB as positive compound (IC50=130μM). Most compounds exhibited excellent...
  13. ARMc8: a potential diagnostic and therapeutic target for cancers-reply.

    Human Pathology 54:201 (2016) PMID 27036315

  14. Ectopic Expression of DREB Transcription Factor, AtDREB1A, Confers Tolerance to Drought in Transgenic Salvia miltiorrhiza.

    Plant and Cell Physiology 57(8):1593 (2016) PMID 27485523

    Drought decreases crop productivity more than any other type of environmental stress. Transcription factors (TFs) play crucial roles in regulating plant abiotic stress responses. The Arabidopsis thaliana gene DREB1A/CBF3, encoding a stress-inducible TF, was introduced into Salvia miltiorrhiza Ec...
  15. Effects of oocyte vitrification on epigenetic status in early bovine embryos.

    Theriogenology 86(3):868 (2016) PMID 27068359

    Oocyte cryopreservation has a great impact on subsequent embryonic development. Currently, several studies have primarily focused on the consequences of vitrification and the development potential of cellular structures. This study determined whether oocyte vitrification caused epigenetic instab...
  16. Altered structural and functional connectivity between the bilateral primary motor cortex in unilateral subcortical stroke: A multimodal magnetic resonance imaging study.

    Medicine (Baltimore) 95(31):e4534 (2016) PMID 27495109

    A large number of functional imaging studies have focused on the understanding of motor-related neural activities after ischemic stroke. However, the knowledge is still limited in the structural and functional changes of the interhemispheric connections of the bilateral primary motor cortices (M...
  17. Development of an immunochromatographic test strip for simultaneous qualitative and quantitative detection of ochratoxin A and zearalenone in cereal.

    Journal of the Science of Food and Agriculture 96(11):3673 (2016) PMID 26612142

    Ochratoxin A (OTA) and zearalenone (ZEN) are natural products of filamentous fungi that are harmful to humans and animals exposed to them even in extremely low concentration. The immunochromatographic test strip has become a popular diagnostic tool for detecting analytes. Its major advantages ar...
  18. Agronomic nitrogen-use efficiency of rice can be increased by driving OsNRT2.1 expression with the OsNAR2.1 promoter.

    Plant Biotechnology Journal 14(8):1705 (2016) PMID 26826052

    The importance of the nitrate (NO3-) transporter for yield and nitrogen-use efficiency (NUE) in rice was previously demonstrated using map-based cloning. In this study, we enhanced the expression of the OsNRT2.1 gene, which encodes a high-affinity NO3- transporter, using a ubiquitin (Ubi) promot...
  19. MicroRNA-145 Inhibitor Significantly Improves the Development of Bovine Somatic Cell Nuclear Transfer Embryos In Vitro.

    Cellular Reprogramming 18(4):230 (2016) PMID 27459582

    Directly regulating the translation of POU5F1, SOX2, KLF4, and miRNA-145 plays an important role in maintaining the pluripotency of stem cells and the development of early embryos. In the present study, the expression model of miRNA-145 on bovine somatic cell nuclear transfer (SCNT) and in vitro...
  20. Decreased microRNA miR-181c expression in peripheral blood mononuclear cells correlates with elevated serum levels of IL-7 and IL-17 in patients with myasthenia gravis.

    Clinical and Experimental Medicine 16(3):413 (2016) PMID 25962782

    miR-181c is a newly identified negative regulator of immune cell activation. In this study, we aimed to investigate the expression and functional role of miR-181c in myasthenia gravis (MG). miR-181c showed significant downregulation in peripheral blood mononuclear cells (PBMCs) from MG patients ...