1. KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.

    Journal of Histochemistry & Cytochemistry 62(2):145 (2014) PMID 24152993 PMCID PMC3902094

    Keratan sulfate (KS) comprises repeating disaccharides of galactose (Gal) and N-acetylglucosamine (GlcNAc). Residues of Gal and GlcNAc in KS are potentially modified with sulfate at their C-6 positions. The 5D4 monoclonal antibody recognizes KS structures containing Gal and GlcNAc, both 6-sulfat...
  2. KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.

    Journal of Histochemistry & Cytochemistry 62(2):145 (2014) PMID 24152993 PMCID PMC3902094

    Keratan sulfate (KS) comprises repeating disaccharides of galactose (Gal) and N-acetylglucosamine (GlcNAc). Residues of Gal and GlcNAc in KS are potentially modified with sulfate at their C-6 positions. The 5D4 monoclonal antibody recognizes KS structures containing Gal and GlcNAc, both 6-sulfat...
  3. KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.

    Journal of Histochemistry & Cytochemistry 62(2):145 (2014) PMID 24152993 PMCID PMC3902094

    Keratan sulfate (KS) comprises repeating disaccharides of galactose (Gal) and N-acetylglucosamine (GlcNAc). Residues of Gal and GlcNAc in KS are potentially modified with sulfate at their C-6 positions. The 5D4 monoclonal antibody recognizes KS structures containing Gal and GlcNAc, both 6-sulfat...
  4. Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.

    Journal of neuroinflammation 9:220 (2012) PMID 22989354 PMCID PMC3511294

    The neuronal microtubule-associated protein tau becomes hyperphosphorylated and forms aggregates in tauopathies but the processes leading to this pathological hallmark are not understood. Because tauopathies are accompanied by neuroinflammation and the complement cascade forms a key innate immun...
  5. P2-294: Microarray profiling reveals autoantibody reactivities against abnormal amyloid peptide conformations decline with age and in Alzheimer's disease

    Alzheimer's & Dementia 4(4):T458 (2008)

  6. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins.

    Nature Medicine 13(11):1359 (2007) PMID 17934472

    A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 signaling proteins in blood plasma that can be used to classify blinded samples from Alzheimer's and control subjects with close to 90% accuracy and to identify patients who had mild cognitive impa...