1. Engineering protein folding and translocation improves heterologous protein secretion in Saccharomyces cerevisiae.

    Biotechnology and Bioengineering 112(9):1872 (2015) PMID 25850421

    Saccharomyces cerevisiae is widely used as a producer of heterologous proteins of medical and industrial interest. Numerous efforts have been made to overcome bottlenecks in protein expression and secretion. However, the effect of engineering protein translocation to heterologous protein secreti...
  2. Data set for cloning and characterization of heterologous transporters in Saccharomyces cerevisiae and identification of important amino acids for xylose utilization.

    Data in Brief 4:119 (2015) PMID 26217774 PMCID PMC4510445

    The efficient uptake is important for the xylose utilization by Saccharomyces cerevisiae. A heterogenous transporter Mgt05196p was cloned from Meyerozyma guilliermondii and expressed in Saccharomyces cerevisiae[1]. This data article contains the transport characteristics of Mgt05196p in S. cerev...
  3. Microbial communities, extracellular proteomics and polysaccharides: A comparative investigation on biofilm and suspended sludge.

    Bioresource Technology 190:21 (2015) PMID 25919933

    Biofilm and suspended sludge (S-sludge) floc exhibit distinct physicochemical properties and process performances in an integrated fixed-film and suspended growth sequencing batch reactor. However, the mechanisms of governing these differences between the two aggregates were unknown. Current wor...
  4. Mechanobiology of mesenchymal stem cells: Perspective into mechanical induction of MSC fate.

    Acta Biomaterialia 20:1 (2015) PMID 25871537

    Bone marrow-derived mesenchymal stem and stromal cells (MSCs) are promising candidates for cell-based therapies in diverse conditions including tissue engineering. Advancement of these therapies relies on the ability to direct MSCs toward specific cell phenotypes. Despite identification of appli...
  5. Erratum to: Overall survival differences between patients with inflammatory and noninflammatory breast cancer presenting with distant metastasis at diagnosis.

    Breast Cancer Research and Treatment 152(2):417 (2015) PMID 26092296

  6. Overall survival differences between patients with inflammatory and noninflammatory breast cancer presenting with distant metastasis at diagnosis.

    Breast Cancer Research and Treatment 152(2):407 (2015) PMID 26017070 PMCID PMC4492876

    Inflammatory breast cancer (IBC) is a rare and aggressive disease. Previous studies have shown that among patients with stage III breast cancer, IBC is associated with a worse prognosis than noninflammatory breast cancer (non-IBC). Whether this difference holds true among patients with stage IV ...
  7. Cloning and characterization of heterologous transporters in Saccharomyces cerevisiae and identification of important amino acids for xylose utilization.

    Metabolic Engineering 30:79 (2015) PMID 25944766

    Efficient and specific transporters may enhance pentose uptake and metabolism by Saccharomyces cerevisiae. Eight heterologous sugar transporters were characterized in S. cerevisiae. The transporter Mgt05196p from Meyerozyma guilliermondii showed the highest xylose transport activity among them. ...
  8. Electrospun fibers based on polyvinyl pyrrolidone/Eu-polyethylene glycol as phase change luminescence materials

    Materials Letters 147:113 (2015)

    In this study, luminescent electrospun nanofibers based on polyvinyl pyrrolidone (PVP)/Eu-PEG were prepared through the materials processing technique of electrospinning as an innovative type of phase change materials (PCMs). Eu-PEG phase-change luminescent material was prepared by coo...
  9. Electrospun fibers based on polyvinyl pyrrolidone/Eu-polyethylene glycol as phase change luminescence materials

    Materials Letters 147:113 (2015)

    In this study, luminescent electrospun nanofibers based on polyvinyl pyrrolidone (PVP)/Eu-PEG were prepared through the materials processing technique of electrospinning as an innovative type of phase change materials (PCMs). Eu-PEG phase-change luminescent material was prepared by coo...
  10. The yeast BDF1 regulates endocytosis via LSP1 under salt stress.

    Current Microbiology 70(5):671 (2015) PMID 25572496

    Bromodomain-containing transcription factor, a kind of important regulating protein, can recognize and bind to acetylated histone. The homologous genes, BDF1 and BDF2, in Saccharomyces cerevisiae, respectively, encode a bromodomain-containing transcription factor. Previously study has demonstrat...
  11. [Comparison of single versus and multi-level vertebral compression fractures in elders].

    Zhonghua Yixue Zazhi 95(15):1158 (2015) PMID 26081360

    To compare the characteristics, causes and relationship to osteoporosis between single and multi-level vertebral compression fractures in elders. A total of 126 subjects (147 vertebrae) with acute back pain between September 2010 and December 2012 were diagnosed as vertebral fracture through mag...
  12. Fabrication, formation mechanism and the application in lithium-ion battery of porous Fe2O3 nanotubes via single-spinneret electrospinning

    Electrochimica Acta 158:105 (2015)

    Porous Fe2O3 nanobelts and nanotubes have been controllably fabricated by annealing the different electrospun precursor nanofibers. When evaluated as a anode material for lithium-ion batteries, the porous Fe2O3 nanotubes exhibit good lithium storage performances. [Display om...
  13. Fabrication, formation mechanism and the application in lithium-ion battery of porous Fe2O3 nanotubes via single-spinneret electrospinning

    Electrochimica Acta 158:105 (2015)

    Porous Fe2O3 nanobelts and nanotubes have been controllably fabricated by annealing the different electrospun precursor nanofibers. When evaluated as a anode material for lithium-ion batteries, the porous Fe2O3 nanotubes exhibit good lithium storage performances. [Display om...
  14. Long-term toxicity study of rAd5-hTERTC27 in SD rats and Cynomolgus monkeys by intravenous injection.

    Regulatory Toxicology and Pharmacology 71(2):285 (2015) PMID 25592546

    rAd5-hTERTC27, a replication-defective adenovirus vector carrying hTERTC27, has been proposed for possible use against hepatocellular carcinoma (HCC). In this study, we investigated the long-term toxicity of rAd5-hTERTC27 in SD rats and Cynomolgus monkeys. rAd5-hTERTC27 was administered intraven...
  15. Optimal Magnetic Resonance Perfusion Thresholds Identifying Ischemic Penumbra and Infarct Core: A Chinese Population-based Study.

    CNS Neuroscience & Therapeutics 21(3):289 (2015) PMID 25476071

    To validate whether the optimal magnetic resonance perfusion (MRP) thresholds for ischemic penumbra and infarct core, between voxel and volume-based analysis, are varied greatly among Chinese acute ischemic stroke patients. Acute ischemic stroke patients receiving intravenous thrombolysis within...
  16. Role of Krüppel-like factors in cancer stem cells.

    Journal of Physiology and Biochemistry 71(1):155 (2015) PMID 25616500

    Cancer stem cells (CSCs), or cancer cells with stem cell properties, are a rare population of tumor bulk and are recognized to be responsible for cancer recurrence, drug resistance, and metastasis. However, the molecular mechanisms of how to regulate the differentiation and self-renewing of CSCs...
  17. Evaluation of industrial Saccharomyces cerevisiae strains as the chassis cell for second-generation bioethanol production.

    Microbial Biotechnology 8(2):266 (2015) PMID 25616171 PMCID PMC4353340

    To develop a suitable Saccharomyces cerevisiae industrial strain as a chassis cell for ethanol production using lignocellulosic materials, 32 wild-type strains were evaluated for their glucose fermenting ability, their tolerance to the stresses they might encounter in lignocellulosic hydrolysate...
  18. Excitatory Synaptic Function and Plasticity is Persistently Altered in Ventral Tegmental Area Dopamine Neurons after Prenatal Ethanol Exposure.

    PMID 25284318 PMCID PMC4330503

    Prenatal ethanol exposure (PE) is one of the developmental factors leading to increased addiction propensity (risk). However, the neuronal mechanisms underlying this effect remain unknown. We examined whether increased excitatory synaptic transmission in ventral tegmental area (VTA) dopamine (DA...
  19. Role of Krüppel-like factors in cancer stem cells.

    Journal of Physiology and Biochemistry 71(1):155 (2015) PMID 25616500

    Cancer stem cells (CSCs), or cancer cells with stem cell properties, are a rare population of tumor bulk and are recognized to be responsible for cancer recurrence, drug resistance, and metastasis. However, the molecular mechanisms of how to regulate the differentiation and self-renewing of CSCs...
  20. Long-term toxicity study of rAd5-hTERTC27 in SD rats and Cynomolgus monkeys by intravenous injection

    Regulatory Toxicology and Pharmacology 71(2):285 (2015)

    • We investigated the long-term toxicity of rAd5-hTERTC27 for possible use against HCC. • All animals displayed overall good health during the 16-week trial period...