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Annales d'Endocrinologie

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  1. Neuro-ophthalmologic exploration in non-functioning pituitary adenoma.

    Annales d'Endocrinologie 76(3):210 (2015) PMID 26070465

    Non-functioning pituitary adenoma may lead to blindness and causes visual impairment in 58% of cases and, more rarely, ocular motor disorder. Patients are slow to become aware of their visual dysfunction, vision in one eye compensating the deficit in the other. Assessment of visual function, com...
  2. Biological and radiological exploration and management of non-functioning pituitary adenoma.

    Annales d'Endocrinologie 76(3):201 (2015) PMID 26122495

    Non-functioning pituitary adenoma may be totally asymptomatic and discovered "incidentally" during radiological examination for some other indication, or else induce tumoral signs with compression of the optic chiasm and pituitary dysfunction. Non-functioning adenomas are mainly gonadotroph, but...
  3. Panhypopituitarism revealing sellar tuberculoma.

    Annales d'Endocrinologie 76(3):286 (2015) PMID 26122494

  4. Post-surgical management of non-functioning pituitary adenoma.

    Annales d'Endocrinologie 76(3):228 (2015) PMID 26116412

    Post-surgical surveillance of non-functioning pituitary adenoma (NFPA) is based on magnetic resonance imaging (MRI) at 3 or 6 months then 1 year. When there is no adenomatous residue, annual surveillance is recommended for 5 years and then at 7, 10 and 15 years. In case of residue or doubtful MR...
  5. Management of clinically non-functioning pituitary adenoma.

    Annales d'Endocrinologie 76(3):239 (2015) PMID 26072284

    Clinically NFPA is currently the preferred term for designing all the pituitary adenomas which are not hormonally active (in other words, not associated with clinical syndromes such as amenorrhea-galactorrhea in the context of prolactinomas, acromegaly, Cushing's disease or hyperthyroidism secon...
  6. Neurocognitive outcomes of children secondary to mild iodine deficiency in pregnant women.

    Annales d'Endocrinologie 76(3):248 (2015) PMID 25934357

    Iodine deficiency is the most important preventable cause of brain damage worldwide. During pregnancy, severe iodine deficiency causes endemic cretinism, whereas mild-to-moderate iodine deficiency impairs neurocognitive function of the offspring. Numerous reports demonstrate the impact of iodine...
  7. Non-functioning pituitary adenoma: When and how to operate? What pathologic criteria for typing?

    Annales d'Endocrinologie 76(3):220 (2015) PMID 26070464

    After diagnosis of non-functioning pituitary adenoma and impact assessment (pituitary deficiency, visual field disorder), the question of management arises between surgery and surveillance. This part of the Consensus document aims to clarify the principal situations encountered in clinical pract...
  8. Association of metabolic syndrome with testosterone and inflammation in men.

    Annales d'Endocrinologie 76(3):260 (2015) PMID 26142486

    There is limited data on the assessment of relationship between sex hormones, metabolic syndrome (MS) and inflammation. Therefore, our objective was to examine the relationship between metabolic syndrome, testosterone and inflammation. It was a cross-sectional study which included 309 subjects i...
  9. The history of Distilbène(®) (Diethylstilbestrol) told to grandchildren - the transgenerational effect.

    Annales d'Endocrinologie 76(3):253 (2015) PMID 25934356

    The Distilbène(®) story is a dramatic episode which belongs to the history of medicine. It provided several useful lessons such as the importance of evidence-based medicine and the hazard to develop treatments during pregnancy without careful animal verifications. However, this experience has al...
  10. Management of nonfunctioning pituitary incidentaloma.

    Annales d'Endocrinologie 76(3):191 (2015) PMID 26054868

    Prevalence of pituitary incidentaloma is variable: between 1.4% and 27% at autopsy, and between 3.7% and 37% on imaging. Pituitary microincidentalomas (serendipitously discovered adenoma <1cm in diameter) may increase in size, but only 5% exceed 10mm. Pituitary macroincidentalomas (serendipitous...