Annales d'Endocrinologie

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  1. McCune-Albright syndrome, natural history and multidisciplinary management in a series of 14 pediatric cases.

    Annales d'Endocrinologie 77(1):7 (2016) PMID 26850292

    McCune-Albright syndrome is a rare disorder characterized by endocrine disorders, café-au-lait spots and fibrous dysplasia of bone that occurs early in life. A series of 14 pediatric cases were followed between 1994 and 2013 by the competence center for rare endocrine diseases and constitutional...
  2. Risk of hormonotherapy in transgender people: Literature review and data from the French Database of Pharmacovigilance.

    Annales d'Endocrinologie 77(1):14 (2016) PMID 26830952

    After the diagnosis of transsexualism, hormone therapy is an established stage of gender identity disorder treatment for inducing secondary sex characteristic development of the target gender while reducing that of the birth sex. The aim of this study was to review existing data about the risk o...
  3. Performance of the 4-mg intravenous dexamethasone suppression test in differentiating Cushing disease from pseudo-Cushing syndrome.

    Annales d'Endocrinologie 77(1):30 (2016) PMID 26656734

    Discriminating Cushing disease (CD) from pseudo-Cushing syndrome (PCS) is a challenging task that may be overcome with the 4-mg intravenous (IV) dexamethasone suppression test (DST). Assess the performance of the 4-mg IV DST in the differential diagnosis between CD and PCS in well-characterized ...
  4. Thyroid side effects prophylaxis in front of nuclear power plant accidents.

    Annales d'Endocrinologie 77(1):1 (2016) PMID 26830953

    The better knowledge of the mechanisms of nuclear incidents and lessons learned from accidents in the recent past to improve the effectiveness of measures taken following a nuclear accident exposure to fallout of radioactive iodine isotopes. Thus, immediate, passive measures, such as containment...
  5. New adipokines.

    Annales d'Endocrinologie 77(1):49 (2016) PMID 26852251

    Adipose tissue is now widely recognized as "an organ" able to synthesize and secrete hundred factors collectively called adipokines. These secreted molecules exert pleiotropic actions, notably on the regulation of glucose and lipid metabolism, inflammation, reproduction, or angiogenesis. Over th...
  6. Pheochromocytoma in a 45 X, iso (Xq) Turner syndrome.

    Annales d'Endocrinologie 77(1):57 (2016) PMID 26874993

  7. High prevalence of autoimmune thyroid diseases in patients with prolactinomas: A cross-sectional retrospective study in a single tertiary referral centre.

    Annales d'Endocrinologie 77(1):37 (2016) PMID 26874995

    Prolactin has been shown to exert potent immunomodulatory activities. Retrospective cross-sectional study examining the prevalence of autoimmune thyroid diseases (AITD) in patients with prolactinomas. The medical files of 462 patients (367 women and 95 men) followed up at a single tertiary refer...
  8. Differential expression network analysis for diabetes mellitus type 2 based on expressed level of islet cells.

    Annales d'Endocrinologie 77(1):22 (2016) PMID 26874994

    Diabetes mellitus type 2 (T2DM) is a metabolic disease that has become a pressing issue, with potential adverse impact on mental health. We aimed to explore the potential molecular mechanism of T2DM. GSE38642 microarray data downloaded from gene expression omnibus was used to identify the differ...
  9. Role of mass spectrometry in steroid assays.

    Annales d'Endocrinologie 77(1):43 (2016) PMID 26872617

    In addition to protein hormones, steroids measurement constitutes the basis of modern endocrinology. Immunoassays have shown their limits in this field. In contrast, mass spectrometry shows an excellent sensitivity and specificity that make it the method of choice for steroids assays. The recent...
  10. Pegvisomant treatment in patients with acromegaly in clinical practice: The French ACROSTUDY.

    Annales d'Endocrinologie 76(6):664 (2015) PMID 26596374

    To monitor long-term pegvisomant treatment of patients with acromegaly in routine clinical practice. The French ACROSTUDY is part of the global ACROSTUDY, an observational post-authorization safety surveillance study of acromegaly treatment with pegvisomant. The median duration of follow-up of t...
  11. Upper gastrointestinal haemorrhage due to a small extra-papillary duodenal neuroendocrine tumour expressing somatostatin.

    Annales d'Endocrinologie 76(6):697 (2015) PMID 26593862

  12. Questioning the pathogenic role of the pTyr791Phe mutation of the RET proto-oncogene: Insight from a case report.

    Annales d'Endocrinologie 76(6):690 (2015) PMID 26639185

    The pTyr791Phe mutation of the RET proto-oncogene is associated with a low penetrance of medullar thyroid carcinoma (MTC). Thus, there is a lack in guidelines on management of these patients presenting without a thyroid disease. A 27-year-old woman presented with a history of severe hypertension...
  13. Insulin antibodies in patients with type 2 diabetic receiving recombinant human insulin injection: A report of 12 cases.

    Annales d'Endocrinologie 76(6):694 (2015) PMID 26607016

    We report 12 cases of patients with type 2 diabetic receiving recombinant human insulin injection, who had uncontrolled hyperglycemia or frequent episodes of hypoglycemia, high levels of serum insulin and positive insulin antibodies. The clinical characteristics and insulin antibodies pharmacoki...
  14. Pituitary gigantism: Causes and clinical characteristics.

    Annales d'Endocrinologie 76(6):643 (2015) PMID 26585365

    Acromegaly and pituitary gigantism are very rare conditions resulting from excessive secretion of growth hormone (GH), usually by a pituitary adenoma. Pituitary gigantism occurs when GH excess overlaps with the period of rapid linear growth during childhood and adolescence. Until recently, its e...
  15. Analysis of FMR1 gene premutation and X chromosome cytogenetic abnormalities in 100 Tunisian patients presenting premature ovarian failure.

    Annales d'Endocrinologie 76(6):671 (2015) PMID 26593861

    To evaluate the prevalence of FMR1 premutations and X chromosome cytogenetic abnormalities in a large cohort of Tunisian women with premature ovarian failure (POF). The cohort consisted of 127 Tunisian women with POF referred by endocrinologists and gynecologists for genetic investigation in the...
  16. Genetic susceptibility to autoimmune thyroid diseases in a Chinese Han population: Role of vitamin D receptor gene polymorphisms.

    Annales d'Endocrinologie 76(6):684 (2015) PMID 26593863

    Previous studies have found that some immune-related genes were associated with autoimmune thyroid diseases (AITDs). A couple of studies have explored the association between vitamin D (1,25-dihydroxyvitamin D3) receptor (VDR) gene polymorphisms and susceptibility to AITDs in different populatio...
  17. Efficacy and safety of denosumab for the treatment of osteoporosis: A systematic review.

    Annales d'Endocrinologie 76(6):650 (2015) PMID 26639186

    Denosumab is an anti-RANK ligand (RANKL) monoclonal antibody approved for the treatment of postmenopausal osteoporosis and prevention of skeletal metastasis complications. Administered subcutaneously every 6 months, it reduces the risk of vertebral fracture by 70% and of hip fracture by 40%. Its...
  18. Evidence of male hypogonadism at an early age as a familial risk of type 2 diabetes.

    Annales d'Endocrinologie 76(6):658 (2015) PMID 26639184

    Previous investigations provide evidence of an association of hypogonadism with type 2 diabetes in men, and low testosterone levels have been regarded a risk factor for the disease. Since a strong genetic predisposition to type 2 diabetes has been demonstrated, here we investigate a possible ten...
  19. Valuable predictive features of relapse of Graves' disease after antithyroid drug treatment.

    Annales d'Endocrinologie 76(6):679 (2015) PMID 26514949

    Antithyroid drug treatment (ATDT) effectively achieves euthyroidism in patients with Graves' disease (GD). However, apparently successful treatment may be followed by relapse. We investigated the outcome of ATDT in Chinese patients with GD to identify predictive features of relapse. In total, 13...
  20. [Genetics of congenital lipodystrophies].

    Annales d'Endocrinologie 76(6 Suppl 1):S2 (2015) PMID 26776286

    Congenital lipodystrophies are heterogeneous genetic diseases, leading to the loss of adipose tissue. This loss of adipose tissue can be generalized or partial, thus defining different phenotypes. These lipodystrophies have a major metabolic impact, secondary to lipotoxicity. This lipotoxicity i...