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Biochimica et Biophysica Acta

Print ISSN
0006-3002
Publisher
Sciencedirect
URL
http://www.sciencedirect.com/science/journal/00063002
Usage rank
5494
Article count
89807
Free count
396
Free percentage
0.00440946
PDFs via platforms
Sciencedirect

  1. Participation of thioredoxin in the V(V)-reduction reaction by Vanabin2.

    Biochimica et Biophysica Acta 1840(11):3238 (2014) PMID 25108063

    It is well-understood that ascidians accumulate high levels of vanadium, a reduced form of V(III), in an extremely acidic vacuole in their blood cells. Vanabins are small cysteine-rich proteins that have been identified only from vanadium-rich ascidians. A previous study revealed that Vanabin2 can a...
  2. Regulation of cytokinesis in the milk yeast Kluyveromyces lactis.

    Biochimica et Biophysica Acta 1843(11):2685 (2014) PMID 25110348

    We investigated the effects of various deletion mutants on cytokinesis in the milk yeast Kluyveromyces lactis. To determine the spatiotemporal parameters of cytokinesis components, live-cell imaging of fluorophor-tagged KlMyo1 and a new Lifeact probe for KlAct1 was employed. In contrast to Saccharom...
  3. D2N: Distance to the native.

    Biochimica et Biophysica Acta 1844(10):1798 (2014) PMID 25062912

    We report the development of a metric "D2N" (distance to the native) - that predicts the "RMSD" of any structure without actually knowing the native structure. By combining physico-chemical properties and known universalities in spatial organization of soluble proteins to develop D2N, we demonstrate...
  4. Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRSF3 through interaction with exon 8.

    Biochimica et Biophysica Acta 1839(1):25 (2014) PMID 24321384

    We show that knockdown of SRSF3 (also known as SRp20) with siRNA induced significant increase of endogenous exon 9 inclusion. In addition, overexpression of SRSF3 promoted exon 9 skipping. Thus we conclude that SRSF3 promotes exon 9 skipping. In order to understand the functional target of SRSF3 on...
  5. Targeting epigenetic mediators of gene expression in thoracic malignancies.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1819(7):836 (2012) PMID 22507242

    Lung and esophageal cancer and malignant pleural mesotheliomas are highly lethal neoplasms that are leading causes of cancer-related deaths worldwide. Presently, limited information is available pertaining to epigenetic mechanisms mediating initiation and progression of these neoplas...
  6. Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1822(6):996 (2012) PMID 22434064

    The ATP-binding cassette, sub-family B member 4 knock-out mouse (Abcb4(-/-)) is a relevant model for chronic cholangiopathy in man. Due to the lack of this P-glycoprotein in the canalicular membrane of hepatocytes, the secretion of phospholipids into bile is absent, resulting in incr...
  7. IQGAP2, A candidate tumour suppressor of prostate tumorigenesis.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1822(6):875 (2012) PMID 22406297

    We report here that IQGAP2 is a candidate tumour suppressor of prostate cancer (PC). Elevated IQGAP2 was detected in prostatic intraepithelial neoplasia (PIN), early stages of PCs (Gleason score ≤3), and androgen-dependent LNCaP PC cells. However, IQGAP2 was expressed at substantially reduced leve...
  8. Regulation of SGLT expression and localization through Epac/PKA-dependent caveolin-1 and F-actin activation in renal proximal tubule cells.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1823(4):971 (2012) PMID 22230192

    This study demonstrated that exchange proteins directly activated by cAMP (Epac) and protein kinase A (PKA) by 8-bromoadenosine (8-Br)-adenosine 3',5'-cyclic monophosphate (cAMP) stimulated [(14)C]-α-methyl-D-glucopyranoside (α-MG) uptake through increased sodium-glucose cotranspor...
  9. Proteasomal AAA-ATPases: structure and function.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1823(1):67 (2012) PMID 21820014

    The 26S proteasome is a chambered protease in which the majority of selective cellular protein degradation takes place. Throughout evolution, access of protein substrates to chambered proteases is restricted and depends on AAA-ATPases. Mechanical force generated through cycles of ATP binding and hydr...
  10. Plastoquinol is more active than α-tocopherol in singlet oxygen scavenging during high light stress of Chlamydomonas reinhardtii.

    Biochimica et Biophysica Acta (BBA) - Bioenerge... 1817(3):389 (2012) PMID 22192719

    We have performed comparative analysis of different prenyllipids in Chlamydomonas reinhardtii cultures during high light stress under variety of conditions (presence of inhibitors, an uncoupler, heavy water). The obtained results indicate that plastoquinol is more active than α-tocopherol in scaven...