British Journal of Nutrition

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  1. Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase.

    British Journal of Nutrition 99(5):945 (2008) PMID 17927845

    The aim of the present study was to confirm that olive oil phenols reduce human platelet aggregability and to verify the hypothesis that cAMP- and cGMP- phosphodiesterases (PDE) could be one of the targets of the biological effect. Four extracts from oils characterized by a high phenol content (...
  2. Energy intake and resting energy expenditure in adult male rats after early postnatal food restriction.

    British Journal of Nutrition 99(5):1149 (2008) PMID 17925052

    Both in man and in animal models, changes in food intake and body composition in later life have been reported after alterations in perinatal nutrition. Therefore, we hypothesised that early postnatal undernutrition in the rat induces permanent changes in energy balance. Food restriction (FR) du...
  3. Postprandial oxidative stress is exacerbated in cigarette smokers.

    British Journal of Nutrition 99(5):1055 (2008) PMID 17925054

    Both cigarette smoking and high fat meals induce oxidative stress, which is associated with the pathogenesis of numerous diseases. We compared blood antioxidant status, oxidative stress biomarkers and TAG in twenty smokers and twenty non-smokers, matched for age and physical activity, in respons...
  4. Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort.

    British Journal of Nutrition 99(5):1061 (2008) PMID 18197989

    Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large repres...
  5. Carbohydrate intake and incidence of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.

    British Journal of Nutrition 99(5):1107 (2008) PMID 17988431

    It remains unclear what long-term effects of substituting carbohydrates at the expense of protein or fat may have with regard to diabetes risk. Our objective was to evaluate carbohydrate intake in predicting type 2 diabetes using substitution models for fat and protein. We conducted a prospectiv...
  6. Inulin results in increased levels of beta-catenin and cyclin D1 as the adenomas increase in size from small to large in the Min/+ mouse.

    British Journal of Nutrition 99(5):963 (2008) PMID 17977470

    The mechanism that drives the growth of some colonic adenomas towards malignancy, while permitting others to remain for decades in quiescence, remains unknown. Diets can alter the growth rate of intestinal tumours but it is still unknown whether diets are able to alter the molecular biology of t...
  7. Dose-dependent effects of docosahexaenoic acid-rich fish oil on erythrocyte docosahexaenoic acid and blood lipid levels.

    British Journal of Nutrition 99(5):1083 (2008) PMID 17977469

    Consumption of long-chain n-3 PUFA, particularly DHA, has been shown to improve cardiovascular risk factors but the intake required to achieve benefits is unclear. We sought to determine the relationship between DHA intake, increases in erythrocyte DHA content and changes in blood lipids. A tota...
  8. Nutrient utilisation and intestinal fermentation are differentially affected by the consumption of resistant starch varieties and conventional fibres in pigs.

    British Journal of Nutrition 99(5):984 (2008) PMID 18005479

    This study examined the influence of different resistant starch (RS) varieties and conventional fibres on the efficiency of nutrient utilisation and intestinal fermentation in pigs. Thirty-six pigs (30 kg) were fed poultry meal-based diets supplemented with 10 % granular resistant corn starch (G...
  9. DNA repair phenotype and dietary antioxidant supplementation.

    British Journal of Nutrition 99(5):1018 (2008) PMID 17925050

    Phytochemicals may protect cellular DNA by direct antioxidant effect or modulation of the DNA repair activity. We investigated the repair activity towards oxidised DNA in human mononuclear blood cells (MNBC) in two placebo-controlled antioxidant intervention studies as follows: (1) well-nourishe...
  10. A randomised controlled trial investigating the effect of an intensive lifestyle intervention v. standard care in adults with type 2 diabetes immediately after initiating insulin therapy.

    British Journal of Nutrition 99(5):1025 (2008) PMID 18197995

    Obesity and type 2 diabetes are inextricably linked. It is therefore unfortunate that insulin, the ultimate treatment to improve glycaemic control in type 2 diabetes, is associated with significant weight gain. The aim of the present investigation was to ascertain whether a dietitian-led intensi...
  11. Multivitamin and dietary supplements, body weight and appetite: results from a cross-sectional and a randomised double-blind placebo-controlled study.

    British Journal of Nutrition 99(5):1157 (2008) PMID 17977472

    Two studies were conducted to compare characteristics of consumers and non-consumers of vitamin and/or dietary supplements (study 1) and to assess the effect of a multivitamin and mineral supplementation during a weight-reducing programme (study 2). Body weight and composition, energy expenditur...
  12. Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats.

    British Journal of Nutrition 99(5):1013 (2008) PMID 17977471

    Despite adequate scientific evidence of the potential benefits of probiotics to human health or disease prevention, their contribution to the growth of adipose tissue remains to be established. Four-week-old male Sprague-Dawley rats were fed a diet containing skim milk (control diet) or skim mil...
  13. Relationship between energy from added sugars and frequency of added sugars intake in Irish children, teenagers and adults.

    British Journal of Nutrition 99(5):1117 (2008) PMID 18096092

    A WHO report on diet, nutrition and the prevention of chronic diseases recommended that frequency of consumption of foods and/or drinks containing free sugars should be limited to a maximum of four times per d. In addition, they recommended a reduction in the intake of free sugars to a maximum o...
  14. Vitamin D status in Sri Lankans living in Sri Lanka and Norway.

    British Journal of Nutrition 99(5):941 (2008) PMID 18096090

    Vitamin D deficiency is common in non-Western immigrant groups living in Western countries. A comparison of vitamin D status in individuals who have emigrated and individuals who remain in their country of origin is needed in order to provide information about the effect of moving to northern la...
  15. Genistein and daidzein induced apoA-1 transactivation in hepG2 cells expressing oestrogen receptor-alpha.

    British Journal of Nutrition 99(5):1007 (2008) PMID 18005483

    Studies have shown that soya consumption has been associated with low incidence of CVD. Because the chemical structures of soya isoflavones are similar to oestrogen, the beneficial outcome may be attributed to the oestrogenicity of these compounds. In this study, effect of the soya isoflavone ge...
  16. Identification and reproducibility of dietary patterns in a Danish cohort: the Inter99 study.

    British Journal of Nutrition 99(5):1089 (2008) PMID 17953790

    We aimed to identify dietary patterns in a Danish adult population and assess the reproducibility of the dietary patterns identified. Baseline data of 3,372 women and 3,191 men (30-60 years old) from the population-based survey Inter99 was used. Food intake, assessed by a FFQ, was aggregated int...
  17. The acute effects of psyllium on postprandial lipaemia and thermogenesis in overweight and obese men.

    British Journal of Nutrition 99(5):1068 (2008) PMID 18005484

    Overweight and obesity is one of the risk factors for developing CVD. At present, very little is known about the acute effects of dietary fibre on lipids, glucose and insulin, resting energy expenditure and diet-induced thermogenesis in overweight and obese individuals. This study examined the p...
  18. A comparison of methods to assess changes in dietary patterns from pregnancy to 4 years post-partum obtained using principal components analysis.

    British Journal of Nutrition 99(5):1099 (2008) PMID 17916275 PMCID PMC2493053

    Few studies have examined the longitudinal nature of dietary patterns obtained using principal components analysis (PCA); the methods used are inconsistent. This paper investigates the methodologies used to assess stability and changes in such patterns. Pregnant women recorded frequency of consu...
  19. Effect of iron supplementation during pregnancy on the behaviour of children at early school age: long-term follow-up of a randomised controlled trial.

    British Journal of Nutrition 99(5):1133 (2008) PMID 17967217

    Although routine Fe supplementation in pregnancy is a common practice, its clinical benefits or risks are uncertain. Children born to mothers in the Fe group in a trial of Fe supplementation in pregnancy have been found to have a significantly higher risk of abnormal behaviour at 4 years of age ...
  20. Breastfeeding rates and duration in Germany: a Bavarian cohort study.

    British Journal of Nutrition 99(5):1127 (2008) PMID 18294424

    Breastfeeding is the recommended feeding for all healthy infants. The aim of our study was to assess the current state of breastfeeding prevalence, duration and behaviour in Bavaria, Germany as a basis for targeting breastfeeding promotion measures. The Bavarian Breastfeeding Study is a prospect...