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British Journal of Nutrition

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  1. Trans-polar-fat: all Inuit are not equal.

    British Journal of Nutrition 100(4):703 (2009) PMID 18377680

    As part of the rapid socio-cultural transition observed in Arctic populations, the Inuit diet is changing. We present original data derived from the baseline Inuit Health in Transition cohort study regarding biological levels of n-3 fatty acids and trans-fatty acids (TFA), lipids with opposite h...
  2. Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase.

    British Journal of Nutrition 99(5):945 (2008) PMID 17927845

    The aim of the present study was to confirm that olive oil phenols reduce human platelet aggregability and to verify the hypothesis that cAMP- and cGMP- phosphodiesterases (PDE) could be one of the targets of the biological effect. Four extracts from oils characterized by a high phenol content (...
  3. Energy intake and resting energy expenditure in adult male rats after early postnatal food restriction.

    British Journal of Nutrition 99(5):1149 (2008) PMID 17925052

    Both in man and in animal models, changes in food intake and body composition in later life have been reported after alterations in perinatal nutrition. Therefore, we hypothesised that early postnatal undernutrition in the rat induces permanent changes in energy balance. Food restriction (FR) du...
  4. Postprandial oxidative stress is exacerbated in cigarette smokers.

    British Journal of Nutrition 99(5):1055 (2008) PMID 17925054

    Both cigarette smoking and high fat meals induce oxidative stress, which is associated with the pathogenesis of numerous diseases. We compared blood antioxidant status, oxidative stress biomarkers and TAG in twenty smokers and twenty non-smokers, matched for age and physical activity, in respons...
  5. Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort.

    British Journal of Nutrition 99(5):1061 (2008) PMID 18197989

    Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large repres...
  6. Carbohydrate intake and incidence of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.

    British Journal of Nutrition 99(5):1107 (2008) PMID 17988431

    It remains unclear what long-term effects of substituting carbohydrates at the expense of protein or fat may have with regard to diabetes risk. Our objective was to evaluate carbohydrate intake in predicting type 2 diabetes using substitution models for fat and protein. We conducted a prospectiv...
  7. Inulin results in increased levels of beta-catenin and cyclin D1 as the adenomas increase in size from small to large in the Min/+ mouse.

    British Journal of Nutrition 99(5):963 (2008) PMID 17977470

    The mechanism that drives the growth of some colonic adenomas towards malignancy, while permitting others to remain for decades in quiescence, remains unknown. Diets can alter the growth rate of intestinal tumours but it is still unknown whether diets are able to alter the molecular biology of t...
  8. Dose-dependent effects of docosahexaenoic acid-rich fish oil on erythrocyte docosahexaenoic acid and blood lipid levels.

    British Journal of Nutrition 99(5):1083 (2008) PMID 17977469

    Consumption of long-chain n-3 PUFA, particularly DHA, has been shown to improve cardiovascular risk factors but the intake required to achieve benefits is unclear. We sought to determine the relationship between DHA intake, increases in erythrocyte DHA content and changes in blood lipids. A tota...
  9. Nutrient utilisation and intestinal fermentation are differentially affected by the consumption of resistant starch varieties and conventional fibres in pigs.

    British Journal of Nutrition 99(5):984 (2008) PMID 18005479

    This study examined the influence of different resistant starch (RS) varieties and conventional fibres on the efficiency of nutrient utilisation and intestinal fermentation in pigs. Thirty-six pigs (30 kg) were fed poultry meal-based diets supplemented with 10 % granular resistant corn starch (G...
  10. DNA repair phenotype and dietary antioxidant supplementation.

    British Journal of Nutrition 99(5):1018 (2008) PMID 17925050

    Phytochemicals may protect cellular DNA by direct antioxidant effect or modulation of the DNA repair activity. We investigated the repair activity towards oxidised DNA in human mononuclear blood cells (MNBC) in two placebo-controlled antioxidant intervention studies as follows: (1) well-nourishe...