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Clinica Chimica Acta

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  1. Editorial Board
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    Clinica Chimica Acta 436:IFC (2014)

  2. Detection of fetal chromosomal aneuploidies by ms analysis of cell-free fetal nucleic acids in maternal plasma

    Clinica Chimica Acta 411(11-12):1 (2010)

  3. Comparative proteomic profiling of the human lung adenocarcinoma cells (CL 1-0) expressing miR-372
    Lai and Lai

    Clinica Chimica Acta 411(11-12):1 (2010)

  4. An immunonanogold resonance scattering spectral probe for rapid assay of human chorionic gonadotrophin.

    Clinica Chimica Acta 387(1-2):24 (2008) PMID 17936256

    Several assays for human chorionic gonadotrophin (hCG) such as radioimmunoassay and fluorescence immunoassays were reported. So far, there was no report about the immunonanogold resonance scattering spectral (ING-RSS) assay based on the immunoreaction and resonance scattering (RS) effect. Three ING-...
  5. Reference values for high-density lipoprotein particle size and volume by dynamic light scattering in a Brazilian population sample and thei...

    Clinica Chimica Acta 442:63 (2015) PMID 25595435

    We established reference values of mean HDL size and volume in an asymptomatic representative Brazilian population sample (n=590) and their associations with metabolic parameters by gender. Size and volume were determined in HDL isolated from plasma by polyethyleneglycol precipitation of apoB-contai...
  6. Relationship between carotid artery intima-media thickness and small dense low-density lipoprotein cholesterol concentrations measured by ho...

    Clinica Chimica Acta 442:110 (2015) PMID 25603407

    We investigated the association between carotid artery intima-media thickness (IMT) and sdLDL-C concentrations in Japanese subjects. Carotid artery IMT, blood pressure (BP), fasting plasma sdLDL-C, glucose metabolism, lipid, and C-reactive protein concentrations were measured in 97 native Japanese s...
  7. Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: Use of time course analysis to optim...

    Clinica Chimica Acta 442:24 (2015) PMID 25591964 PMCID PMC4339548

    We sought to: (1) develop a new GC based method to measure urinary mannitol, lactulose and sucralose to assess regional and total gut permeability; (2) analyze the kinetics of these sugars in the urine to determine which ratio is useful to represent intestinal permeability; and (3) determine whether...
  8. Validation of a lipoprotein(a) particle concentration assay by quantitative lipoprotein immunofixation electrophoresis.

    Clinica Chimica Acta 439:219 (2015) PMID 25451955

    We have developed a method of determining Lp(a)-P suitable for routine clinical use. Lipoprotein immunofixation electrophoresis (Lipo-IFE) involves rigidly controlled electrophoretic separation of serum lipoproteins, probing with polyclonal apolipoprotein B antibodies, then visualization after stain...
  9. Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity.

    Clinica Chimica Acta 438:126 (2015) PMID 25150729

    We found that the fatty acid profiles after LPS treatment were similar between the conventional single-sample analysis approach and the proposed comparative approach, with a Pearson's correlation coefficient of approximately 0.96. We applied the comparative method to investigate voriconazole-induced...
  10. Prognostic relevance of ischemia-modified albumin and NT-proBNP in patients with peripheral arterial occlusive disease.

    Clinica Chimica Acta 438:255 (2015) PMID 25195005

    Cardiovascular morbidity is high among patients with peripheral arterial occlusive disease (PAOD). The aim of this study was to evaluate the ability of ischemia-modified albumin (IMA), N-terminal proBNP (NT-proBNP), and high-sensitive cardiac Troponin T (hs-cTnT) to predict cardiovascular complicati...