Clinica Chimica Acta
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Identification of IgG-κ type macroprolactin found in the serum of an 8-year-old girl
Clinica Chimica Acta 433:206 (2014)Background We report a case of macroprolactin (macroPRL) in an 8-year-old girl complaining of an enlarged and painful breast who showed elevated PRL levels by enzyme immunoassay.
Kidney protein profiling of Wilms' tumor patients by analysis of formalin-fixed paraffin-embedded tissue samples
Clinica Chimica Acta 433:235 (2014)We tested formalin-fixed paraffin-embedded (FFPE) tissue sections routinely collected for pathological inspection for their use in in-depth-proteomic analyses of WT samples in comparison to fresh frozen specimen. The overlap of the proteins identified was over 65%. Thus we used FFPE material from 7...
Significant elevation of plasma cathepsin B and cystatin C in patients with community-acquired pneumonia.
We identified the relationship between plasma level changes of cathepsin B and cystatin C before and after antibiotic treatment in hospitalized adult patients with community-acquired pneumonia (CAP).
Cervicovaginal interleukin-6 as a predictor of preterm birth in African American women.
Identification of women who will deliver preterm may reduce infant morbidity and mortality. In heterogeneous populations, fetal fibronectin (fFN) and interleukin-6 are excellent predictors of women who will not deliver within two weeks. African-Americans are at higher risk for preterm birth than Cauc...
Detection of fetal chromosomal aneuploidies by ms analysis of cell-free fetal nucleic acids in maternal plasma
Comparative proteomic profiling of the human lung adenocarcinoma cells (CL 1-0) expressing miR-372
Hypothalamic-pituitary-thyroid axis status of humans during development of ageing process.
We have investigated hypothalamic-pituitary-thyroid function in four groups of healthy elderly male humans. Group A (n=18, age range 20-45 years) served as healthy younger controls, group B (n=10, age range 50-60 years), group C (n=15, age range 60-70 years) and group D (n=16, age range 70-85 years)...
A novel frameshift mutation in exon 6 (the site of Asn 291) of the lipoprotein lipase gene in type I hyperlipidemia.
I hyperlipidemic patient at the position of notable amino acid Asn 291. The patient is a 33-year-old male. His body mass index (BMI) was 18.5 kg/m2. The total cholesterol (TC), triglycerides (TG) and high density lipoprotein-cholesterol (HDL-C) concentration from his fasting plasma were 4.8, 11.9 an...
A variation in Bone Alkaline Phosphatase levels that correlates positively with bone loss and normal levels of aminoterminal propeptide of c...
We found that 41 of the 43 patients had BMD z-scores under -2. No significant differences were found in the levels of serum bAP nor in PINP and beta-CTX levels between controls and patients, although values in the AN group were highly variable. All the BMD z-score values were negative, and their abs...
The melanocyte stimulating hormone receptor polymorphism: association of the V92M and A294H alleles with basal cell carcinoma.
We identified the val92met (V92M) and asp294his (A294H) alleles in 311 cases and 190 controls. The cases included four homo- and 53 heterozygotes for V92M and 12 heterozygotes for A294H and two compound heterozygotes (V92M/A294H). Allele frequencies were similar in controls. In the cases, we found n...