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Clinica Chimica Acta

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  1. Identification of IgG-κ type macroprolactin found in the serum of an 8-year-old girl

    Clinica Chimica Acta 433:206 (2014)

    Background We report a case of macroprolactin (macroPRL) in an 8-year-old girl complaining of an enlarged and painful breast who showed elevated PRL levels by enzyme immunoassay.
  2. Kidney protein profiling of Wilms' tumor patients by analysis of formalin-fixed paraffin-embedded tissue samples

    Clinica Chimica Acta 433:235 (2014)

    We tested formalin-fixed paraffin-embedded (FFPE) tissue sections routinely collected for pathological inspection for their use in in-depth-proteomic analyses of WT samples in comparison to fresh frozen specimen. The overlap of the proteins identified was over 65%. Thus we used FFPE material from 7...
  3. Significant elevation of plasma cathepsin B and cystatin C in patients with community-acquired pneumonia.

    Clinica Chimica Acta 413(5-6):630 (2012) PMID 22209964

    We identified the relationship between plasma level changes of cathepsin B and cystatin C before and after antibiotic treatment in hospitalized adult patients with community-acquired pneumonia (CAP).
  4. Cervicovaginal interleukin-6 as a predictor of preterm birth in African American women.

    Clinica Chimica Acta 412(11-12):988 (2011) PMID 21300046

    Identification of women who will deliver preterm may reduce infant morbidity and mortality. In heterogeneous populations, fetal fibronectin (fFN) and interleukin-6 are excellent predictors of women who will not deliver within two weeks. African-Americans are at higher risk for preterm birth than Cauc...
  5. Detection of fetal chromosomal aneuploidies by ms analysis of cell-free fetal nucleic acids in maternal plasma

    Clinica Chimica Acta 411(11-12):1 (2010)

  6. Comparative proteomic profiling of the human lung adenocarcinoma cells (CL 1-0) expressing miR-372
    Lai and Lai

    Clinica Chimica Acta 411(11-12):1 (2010)

  7. Hypothalamic-pituitary-thyroid axis status of humans during development of ageing process.

    Clinica Chimica Acta 288(1-2):137 (1999) PMID 10529465

    We have investigated hypothalamic-pituitary-thyroid function in four groups of healthy elderly male humans. Group A (n=18, age range 20-45 years) served as healthy younger controls, group B (n=10, age range 50-60 years), group C (n=15, age range 60-70 years) and group D (n=16, age range 70-85 years)...
  8. A novel frameshift mutation in exon 6 (the site of Asn 291) of the lipoprotein lipase gene in type I hyperlipidemia.

    Clinica Chimica Acta 285(1-2):173 (1999) PMID 10481934

    I hyperlipidemic patient at the position of notable amino acid Asn 291. The patient is a 33-year-old male. His body mass index (BMI) was 18.5 kg/m2. The total cholesterol (TC), triglycerides (TG) and high density lipoprotein-cholesterol (HDL-C) concentration from his fasting plasma were 4.8, 11.9 an...
  9. A variation in Bone Alkaline Phosphatase levels that correlates positively with bone loss and normal levels of aminoterminal propeptide of c...

    Clinica Chimica Acta 285(1-2):121 (1999) PMID 10481928

    We found that 41 of the 43 patients had BMD z-scores under -2. No significant differences were found in the levels of serum bAP nor in PINP and beta-CTX levels between controls and patients, although values in the AN group were highly variable. All the BMD z-score values were negative, and their abs...
  10. The melanocyte stimulating hormone receptor polymorphism: association of the V92M and A294H alleles with basal cell carcinoma.

    Clinica Chimica Acta 282(1-2):125 (1999) PMID 10340440

    We identified the val92met (V92M) and asp294his (A294H) alleles in 311 cases and 190 controls. The cases included four homo- and 53 heterozygotes for V92M and 12 heterozygotes for A294H and two compound heterozygotes (V92M/A294H). Allele frequencies were similar in controls. In the cases, we found n...