Advanced search×

Clinica Chimica Acta

Print ISSN
Electronic ISSN
Impact factor
Usage rank
Article count
Free count
Free percentage
PDFs via platforms
Sciencedirect, Gale, Rcgp, and Ingenta

  1. Controls to validate plasma samples for cell free DNA quantification

    Clinica Chimica Acta 446:141 (2015) PMID 25896958

    Recent research has focused on the utility of cell free DNA (cfDNA) in serum and plasma for clinical application, especially in oncology. The literature holds promise of cfDNA as a valuable tumour marker to be used for treatment selection, monitoring and follow-up. The results, however...
  2. Melatonin and male reproduction

    Clinica Chimica Acta 446:175 (2015) PMID 25916694

    Melatonin is a neurohormone secreted by the pineal gland whose concentrations in the body are regulated by both the dark–light and seasonal cycles. The reproductive function of seasonal breeding animals is clearly influenced by the circadian variation in melatonin levels. Moreover, a g...
  3. Targeted next-generation sequencing (NGS) of nine candidate genes with custom AmpliSeq in patients and a cardiomyopathy risk group

    Clinica Chimica Acta 446:132 (2015) PMID 25892673

    Background Hypertrophic cardiomyopathy is a common genetic cardiac disease. Prevention and early diagnosis of this disease are very important. Because of the large number of causative genes and the high rate of mutations involved in the pathogenesis of this disease, tradition...
  4. A high-performance liquid chromatography – tandem mass spectrometry – based targeted metabolomics kidney dysfunction marker panel in human urine

    Clinica Chimica Acta 446:43 (2015) PMID 25871999

    Background Previous studies have examined and documented fluctuations in urine metabolites in response to disease processes and drug toxicity affecting glomerular filtration, tubule cell metabolism, reabsorption, oxidative stress, purine degradation, active secretion and kidn...
  5. The External Quality Assessment Scheme (EQAS): Experiences of a medium sized accredited laboratory

    Clinica Chimica Acta 446:61 (2015) PMID 25882227

    Introduction We put forth our experiences of EQAS, analyzed the result discrepancies, reviewed the corrective actions and also put forth strategies for risk identification and prevention of potential errors in a medical laboratory.
  6. Release of cardiac troponin using a high sensitivity assay after exercise: Type 2 acute myocardial infarction?

    Clinica Chimica Acta 446:6 (2015) PMID 25862921

    Background Cardiac troponin is used as a marker for all types of myocardial infarction.
  7. Detection of IgG anti-Domain I beta2 Glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome

    Clinica Chimica Acta 446:201 (2015) PMID 25935129

    Background IgG anti-Domain I (anti-DI) β2 Glycoprotein I (β2GPI) antibodies are associated to thrombotic risk in antiphospholipid syndrome (APS), but their detection is technically difficult. In this study, a chemiluminescent immunoassay (CLIA) was used to evaluate the clinic...
  8. Longitudinal study of circulating miR-122 in a rat model of non-alcoholic fatty liver disease

    Clinica Chimica Acta 446:267 (2015) PMID 25958847

    Background Circulating microRNAs (miRs) may be promising biomarkers for several diseases. We previously found that miR-122 can function as a biomarker for non-alcoholic fatty liver disease (NAFLD). However, little is known regarding the time course of circulating miR-122 leve...
  9. Short-term storage stability of serum angiotensin-converting enzyme (ACE) activity

    Clinica Chimica Acta 446:261 (2015) PMID 25957986

  10. Editorial Board
    Author(s) unavailable

    Clinica Chimica Acta 446:IFC (2015)