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CSA, Rcgp, Proquest, Ingenta, Gale, and Ovid from 2000

  1. Is there a role for inhaled corticosteroids and macrolide therapy in bronchiectasis?

    Drugs 67(7):965 (2007) PMID 17488142

    Bronchiectasis is characterised by permanent dilatation of the bronchi that arises from chronic inflammation predominantly caused by bacterial infection. This condition remains a major cause of excess respiratory morbidity and treatment is generally only partly successful. There is an urgent nee...
  2. Comparative review of the carbapenems.

    Drugs 67(7):1027 (2007) PMID 17488146

    The carbapenems are beta-lactam antimicrobial agents with an exceptionally broad spectrum of activity. Older carbapenems, such as imipenem, were often susceptible to degradation by the enzyme dehydropeptidase-1 (DHP-1) located in renal tubules and required co-administration with a DHP-1 inhibito...
  3. Approaches to prevention of cardiovascular complications and events in diabetes mellitus.

    Drugs 67(7):997 (2007) PMID 17488145

    Diabetes mellitus affects about 8% of the adult population. The estimated number of patients with diabetes, presently about 170 million people, is expected to increase by 50-70% within the next 25 years. Diabetes is an important component of the complex of 'common' cardiovascular risk factors, a...
  4. Treating erectile dysfunction in renal transplant recipients.

    Drugs 67(7):975 (2007) PMID 17488143

    Erectile dysfunction is common in male kidney transplant recipients. Interference with the physiology of erections can be attributed to recipient co-morbidities, the renal transplant operation, medication adverse effects, relationship problems and changes in mental health. A treatment-oriented e...
  5. Controlled hypotension: a guide to drug choice.

    Drugs 67(7):1053 (2007) PMID 17488147

    For half a century, controlled hypotension has been used to reduce bleeding and the need for blood transfusions, and provide a satisfactory bloodless surgical field. It has been indicated in oromaxillofacial surgery (mandibular osteotomy, facial repair), endoscopic sinus or middle ear microsurge...
  6. Quetiapine: a review of its use in the treatment of bipolar depression.

    Drugs 67(7):1077 (2007) PMID 17488148

    Quetiapine (Seroquel) is the only atypical antipsychotic approved in the US for use as monotherapy in both bipolar mania and depression, offering potential compliance advantages. Monotherapy with oral quetiapine 300 mg/day is effective in the treatment of patients with bipolar I or II depression...
  7. Drug therapy for the secondary prevention of stroke in hypertensive patients: current issues and options.

    Drugs 67(7):955 (2007) PMID 17488141

    Hypertension is the major risk factor for ischaemic and haemorrhagic clinical strokes as well as for silent brain infarcts with a continuous association between both systolic and diastolic blood pressures. Epidemiological data highlight the increasing burden to come over the next decades. Withou...
  8. Scleroderma lung: pathogenesis, evaluation and current therapy.

    Drugs 67(7):985 (2007) PMID 17488144

    The lungs are frequently involved in systemic sclerosis ('scleroderma'), a rare, disabling disease of unknown origin, characterised by skin thickening and Raynaud's phenomenon. The pathogenesis of scleroderma is complex, but signs and symptoms of excessive fibrosis, vasculopathy and inflammation...