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Journal of Theoretical Biology

Print ISSN
0022-5193
Electronic ISSN
1095-8541
Impact factor
2.371
Publisher
Sciencedirect
URL
http://www.sciencedirect.com/science/journal/00225193
Usage rank
788
Article count
10892
Free count
90
Free percentage
0.00826295
PDFs via platforms
Ingenta, Sciencedirect from 1961, CSA, Proquest, Gale, and Rcgp

  1. Distribution bias of the sequence matching between exons and introns in exon joint and EJC binding region in C. elegans

    Journal of Theoretical Biology 364:295 (2015)

    We propose a mechanism that there are matching relations between mRNA sequences and corresponding post-spliced introns, and introns play a significant role in the process of gene expression. In order to reveal the sequence matching features, Smith-Waterman local alignment method is used on C. elegan...
  2. The economics of vaccination

    Journal of Theoretical Biology 363:105 (2014)

    We show that his conditions are not necessary for the welfare theorem to hold but that in general, the market yields inefficiently low vaccination uptake. Equilibrium non-optimality may obtain if (i) agents can recover from infection, (ii) vaccines are imperfect, (iii) individuals are ex ante hetero...
  3. Editorial board
    Author(s) unavailable

    Journal of Theoretical Biology 360:IFC (2014)

  4. A study on stability and medical implications for a complex delay model for CML with cell competition and treatment

    Journal of Theoretical Biology 363:30 (2014)

    We study a mathematical model describing the dynamics of leukemic and normal cell populations (stem-like and differentiated) in chronic myeloid leukemia (CML). This model is a system of four delay differential equations incorporating three types of cell division. The competition between normal and l...
  5. Potential non homologous protein targets of mycobacterium tuberculosis H37Rv identified from protein–protein interaction network

    Journal of Theoretical Biology 361:152 (2014)

    We used centrality measures to identify the most central proteins from protein–protein interaction network of mycobacterium tuberculosis H37Rv which was retrieved from STRING database by hypothesizing these proteins would be important to alter the function of the network. We then refined the result...
  6. Editorial board
    Author(s) unavailable

    Journal of Theoretical Biology 359:IFC (2014)

  7. Editorial board
    Author(s) unavailable

    Journal of Theoretical Biology 354:IFC (2014)

  8. Decoding synchronized oscillations within the brain: phase-delayed inhibition provides a robust mechanism for creating a sharp synchrony fil...

    Journal of Theoretical Biology 334:13 (2013) PMID 23747525

    We use a computational and mathematical approach to investigate the efficacy of the phase-delayed inhibition motif in detecting synchronized oscillations. We show that phase-delayed inhibition is capable of creating a synchrony detector with sharp synchrony filtering properties that depend criticall...
  9. Investigating the link between epithelial-mesenchymal transition and the cancer stem cell phenotype: A mathematical approach.

    Journal of Theoretical Biology 265(3):329 (2010) PMID 20648969

    We mathematically investigate the nature of this increase in stem cell activity. A stochastic model is used when small number of cells are under consideration, namely in simulating the mammosphere assay, while a related continuous model is used to probe the dynamics of larger cell populations. Two s...
  10. On the dynamics of the growth plate in primary ossification.

    Journal of Theoretical Biology 265(4):543 (2010) PMID 20665967

    We show that the size of the Proliferative Zone in the growth plate is rather insensitive to variations in the flux coefficients for Ihh and PTHrP at their boundaries. Besides, we also show that the model is also insensitive to large changes in the (comparatively small) critical value of the PTHrP c...