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- Rcgp, Gale, Ingenta, Proquest, CSA, and Sciencedirect from 1962
Liposomes as carriers of the lipid soluble antioxidant resveratrol: Evaluation of amelioration of oxidative stress by additional antioxidant...
Resveratrol (RES) is a well-known antioxidant, yet in combination with other antioxidant vitamins, it was found to be more effective than any of these antioxidants alone. Present work aims to compare the antioxidant actions of resveratrol with and without vitamin C following delivery as liposomes te...
Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone-benzimidazole analogs.
We found that an increase in the number of methyl groups in addition to methoxy substitution at the para position of the benzoyl ring in compound 8n resulted in higher potency compared to 8f. Furthermore, neovessel formation in in vivo systems, such as the chorioallantoic membrane (CAM) and tumor-in...
Retraction: development of paclitaxel loaded NIPAAm/VP polymeric nanoparticles for efficacy enhancement against human cancer therapy.
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. Copyright © 2012. Published by Elsevier Inc. A...
Inhibition of human platelet aggregation by eosinophils.
Our results indicate that eosinophils play a fundamental role in platelet aggregation inhibition. © 2013....
S100B: Role in cardiac remodeling and function following myocardial infarction in diabetes.
We thus examined the effects of targeted deletion of S100B gene on post-MI hearts. Coronary artery ligation or sham was performed 15weeks after streptozotocin (STZ) or vehicle injection in wild-type (WT) and S100B knock-out (BKO) mice. Left ventricular (LV) structural and functional remodeling was s...
Brain regional differences in CB1 receptor adaptation and regulation of transcription.
Cannabinoid CB1 receptors (CB1Rs) are expressed throughout the brain and mediate the central effects of cannabinoids, including Δ(9)-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana. Repeated THC administration produces tolerance to cannabinoid-mediated effects, although th...
Analytical surveillance of emerging drugs of abuse and drug formulations.
Uncontrolled recreational drugs are proliferating in number and variety. Effects of long-term use are unknown, and regulation is problematic, as efforts to control one chemical often lead to several other structural analogs. Advanced analytical instrumentation and methods are continuing to be develo...
TRPV4 partially participates in proliferation of human brain capillary endothelial cells.
We show that TRPV4 activated by 4α-phorbol 12,13-didecanoate (4αPDD) and hypo-osmotic stimulation (HOS) is a regulator of intracellular calcium ([Ca(2+)](i)) in human brain capillary endothelial cells (HBCEs), and its activation can partially regulate cell proliferation of HBCEs. The expression of T...
Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo.
To further investigate the anti-colorectal carcinoma (CRC) effect of Sophoridine (SRI) which is a quinolizidine alkaloid extracted from a traditional Chinese medicine (TCM) Sophora alopecuroides L. and detect the mechanism involved, provide some basis for the development of S. alopecuroides L. The a...
Critical role of intraneuronal Aβ in Alzheimer's disease: technical challenges in studying intracellular Aβ.
We review evidence pointing to the critical role of intraneuronal Aβ in AD and provide insights both into challenges faced in detecting intracellular Aβ and the prion-like properties of Aβ. Immunoprecipitation and Western blot are used for Aβ detection. We highlight that a standard biochemical metho...