Nature

Print ISSN
0028-0836
Electronic ISSN
1476-4687
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36.104
Publisher
nature
URL
http://www.nature.com/nature/
Usage rank
5
Article count
103083
Free count
6953
Free percentage
0.0674505
PDFs via platforms
Nature, Gale, Ovid from 2002, CSA, and Proquest

  1. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

    Nature 450(7170):712 (2007) PMID 18046409

    Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2 diabetes. SIRT1, an NAD+-dependent deacetylase, is a principal modulator of pathways downstream of calorie restriction that produce beneficial effects on glucose homeosta...