Nederlands tijdschrift voor geneeskunde. Amsterdam
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[Intracranial hypotension syndrome following manipulation of the cervical spine].
Chiropractic interventions such as manipulation of the cervical spine can incidentally lead to severe neurological complications. A 63-year-old female patient presented at the Neurology outpatient clinic with a five-week history of severe postural headache, tinnitus and nausea. The onset of these sy...
[Women with chronic constipation: clinical examination is more important than anorectal function testing].
- Chronic constipation is a common disorder, particularly in women and the elderly.- Physical examination of patients with constipation should include rectal examination and in women also vaginal examination.- The patient is asked to relax, contract and bear down on the pelvic floor during inspection...
[Clinical studies in developing countries].
I call for allowing such studies when the registered treatment is locally unavailable. This should be based on the four most important principles of medical ethics: the duty to help patients, avoid harm, justice and respect for autonomy. On the condition, however, that the population in developing c...
[Multidisciplinary practice guideline 'Invasive treatment of spine related low back pain'].
- The practice guideline 'Invasive treatment of spine related low back pain' describes the state of the art regarding the diagnosis and value of invasive treatment after failure of conservative treatment in patients with pain symptoms of facet joint pain, pain in the sacroiliac joint, coccygodynia,...
[Arthroscopic meniscectomy: does it make sense in patients older than 45?].
Meniscus surgery is the most commonly performed surgical procedure in orthopaedics. Almost two-thirds of the patients are over 45 years old. It is not known, however, whether a torn meniscus in older patients is the primary cause of knee pain, or whether the pain is caused by an ongoing degenerative...
[No end to selective publication yet].
Selective publication of complete studies or outcomes within studies hampers unbiased medical decision making. If the available body of evidence does not offer a fair representation of all existing evidence, the true effect of an intervention cannot be judged, possible harmful effect...
[Fertility after high-dose sex steroid treatment to reduce final height].
We compared 239 tall women and 60 tall men treated with high-dose sex steroids during puberty with respectively 174 untreated tall women and 56 untreated tall men. Reproductive history was assessed by interview in addition to ultrasound imaging of the testes or ovaries, endocrine parameters and seme...
[Effect of treatment with growth hormone on mortality in adults with severe growth hormone deficiency].
WE CONCLUDE THAT THE SEX AND THE HETEROGENEOUS NATURE OF THE GROUP OF PATIENTS WITH GROWTH HORMONE DEFICIENCY ARE IMPORTANT FOR THE ASSESSMENT OF THE EFFECT OF GROWTH HORMONE ON MORTALITY. : Conflict of interest: A.A.M. Franken received reimbursement for his activities for the Medicines Evaluation B...
[Determinants for reintegration and sick leave duration in employees with symptoms of a psychological nature].
To examine the associations between sociodemographic, medical, work-related and organisational factors and the moment of first return to work by employees as well as the total duration of sick leave resulting from common mental disorders. Cross-sectional study....
[Parental smoking and vascular damage in their young children].
We used data on smoking behaviour of parents during and after pregnancy from the "WHeezing Illnesses STudy LEidsche Rijn" (WHISTLER)-birth cohort. In 259 participating children who had turned 5 years of age, the carotid artery intima-media thickness (CIMT) and arterial wall distensibility were measu...