Nederlands tijdschrift voor geneeskunde. Amsterdam
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[No end to selective publication yet].
Selective publication of complete studies or outcomes within studies hampers unbiased medical decision making. If the available body of evidence does not offer a fair representation of all existing evidence, the true effect of an intervention cannot be judged, possible harmful effect...
[Fertility after high-dose sex steroid treatment to reduce final height].
We compared 239 tall women and 60 tall men treated with high-dose sex steroids during puberty with respectively 174 untreated tall women and 56 untreated tall men. Reproductive history was assessed by interview in addition to ultrasound imaging of the testes or ovaries, endocrine parameters and seme...
[Effect of treatment with growth hormone on mortality in adults with severe growth hormone deficiency].
WE CONCLUDE THAT THE SEX AND THE HETEROGENEOUS NATURE OF THE GROUP OF PATIENTS WITH GROWTH HORMONE DEFICIENCY ARE IMPORTANT FOR THE ASSESSMENT OF THE EFFECT OF GROWTH HORMONE ON MORTALITY. : Conflict of interest: A.A.M. Franken received reimbursement for his activities for the Medicines Evaluation B...
[Determinants for reintegration and sick leave duration in employees with symptoms of a psychological nature].
To examine the associations between sociodemographic, medical, work-related and organisational factors and the moment of first return to work by employees as well as the total duration of sick leave resulting from common mental disorders. Cross-sectional study....
[Parental smoking and vascular damage in their young children].
We used data on smoking behaviour of parents during and after pregnancy from the "WHeezing Illnesses STudy LEidsche Rijn" (WHISTLER)-birth cohort. In 259 participating children who had turned 5 years of age, the carotid artery intima-media thickness (CIMT) and arterial wall distensibility were measu...
[Basal cell carcinoma: often more than one].
To calculate the cumulative risks and incidence rates for the development of multiple (two or more) basal cell carcinomas (BCC). A retrospective cohort study with data from PALGA, the nationwide network and registry of histopathology and cytopathology in the Netherlan...
[Thromboprophylaxis with low-molecular-weight heparin insufficient in high-risk pregnancy.]
We analysed 34 women (44 pregnancies) with an intermediate risk and 57 women (82 pregnancies) with a high risk of VTE. The incidence of pregnancy-related VTE despite thromboprophylaxis was 5.5% (95% CI: 2.4-12.3). All VTEs occurred in high-risk women, and risk was higher post partum than ante partum...
[Antibiotics in uncomplicated urinary tract infections: no increase in resistance over the past 5 years.]
We analysed 970 urine samples, of which 785 (81%) were considered positive (> 103 cfu/ml). E. coli was identified in 72% of these samples. The percentage ESBL increased between the two surveys (0.1% in 2004 vs 1% in 2009, 95% CI: 0.1-1.9), while no difference in antibiotic susceptibility to the comm...
[Isolated tumour cells: 'seek, and ye shall find']
In a study recently published in this journal, Van der Zaag et al. found that the distinction made by pathologists between micrometastases and isolated tumour cells in lymph nodes of patients with colon cancer was not uniform. Such a classification only has clinical relevance to canc...
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