New England Journal of Medicine
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Hodgkin’s lymphoma affects about 8000 patients a year in the United States, and with available therapies, about 7000 of them will be cured. Although room for improvement still exists, recent clinical research has focused on determining how little therapy can be given to maintain the cu...
Standard prenatal screening for trisomy 21 (Down's syndrome) is based on a combination of maternal age, maternal serum biomarkers, and fetal ultrasonographic findings. Such screening can identify 70 to 90% of fetuses with trisomy 21 with a false positive rate of 2 to 5%.1 Screening tha...
Cost-Effectiveness of Hypertension Therapy According to 2014 Guidelines Special Article, N Engl J Med 2015;372:447-455. In Table 3 (page 452), the unit given below the “Change in Cardiovascular Costs, as Compared with Status Quo” column head should have been “millions of $,” rather tha...
To the Editor: The results of the Suppression of Ovarian Function Trial (SOFT) by Francis et al. (Jan. 29 issue)1 are presented as practice changing. However, we are concerned about the emphasis given to the receipt of adjuvant chemotherapy — which was considered as a proxy for a disea...
To the Editor: Vannucchi et al. (Jan. 29 issue)1 report that ruxolitinib was superior to standard therapy in patients with polycythemia vera who had an inadequate response to or had unacceptable side effects from hydroxyurea. The primary end point included hematocrit control and a redu...
To the Editor: I would caution against concluding, on the basis of the study by Büller et al. (Jan. 15 issue),1 that reducing factor XI levels attenuates the risk of thrombosis without increasing the risk of bleeding. Factor XI deficiency selectively increases the risk of bleeding in t...
A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis Original Article, N Engl J Med 2014;371:1588-1598. In Table 2 (page 1594), the values given in the Control Group column in the third row from the bottom of the table should have been 53/676 (7.8), rather than 753/67...
To the Editor: In the case of a 60-year-old woman with abdominal pain, dyspnea, and diplopia who received a diagnosis of botulism (Jan. 22 issue),1 one of the differential diagnoses was the Guillain–Barré syndrome. We would like to point out that variants of the Guillain–Barré syndrome...
To the Editor: We were struck by the similarity of transient vascular leak in Ebola virus disease (EVD), as reported by Lyon et al. (Dec. 18 issue),1 with that which occurs in dengue. When severe dengue was first described, uncorrected hypovolemia often led to shock, hemorrhage, and de...