Science

Print ISSN
0036-8075
Electronic ISSN
1095-9203
Impact factor
31.377
Publisher
highwire
URL
http://www.sciencemag.org
Usage rank
1
Article count
165826
Free count
1675
Free percentage
0.0101009
PDFs via platforms
Ama, CSA, Endocrine, Rupress, Csh, Aacr, Gale, Highwire, Aaas, Proquest, Jstor, Ovid, and Nephrology

  1. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis.

    Science 295(5552):140 (2002) PMID 11778052

    Tumstatin is a 28-kilodalton fragment of type IV collagen that displays both anti-angiogenic and proapoptotic activity. Here we show that tumstatin functions as an endothelial cell-specific inhibitor of protein synthesis. Through a requisite interaction with alphaVbeta3 integrin, tumstatin inhib...
  2. A unified definition of biosecurity.

    Science 295(5552):44 (2002) PMID 11780645

  3. Successes of newborn screening programs.

    Science 295(5552):44 (2002) PMID 11780647

  4. Solar system exploration. Researchers fear merger could muffle their voice.

    Science 295(5552):37 (2002) PMID 11778024

  5. U.S. budget. Biomedicine gets record raise as Congress sets 2002 spending.

    Science 295(5552):24 (2002) PMID 11778015

  6. Clustered star formation and the origin of stellar masses.

    Science 295(5552):68 (2002) PMID 11778037

    Star clusters are ubiquitous in galaxies of all types and at all stages of their evolution. We also observe them to be forming in a wide variety of environments, ranging from nearby giant molecular clouds to the supergiant molecular clouds found in starburst and merging galaxies. The typical sta...
  7. Partial dissociation of water on Ru(0001).

    Science 295(5552):99 (2002) PMID 11778041

    Initial water deposition on the moderately reactive precious metal surface Ru(0001) has been thought to produce an ice-like bilayer. However, calculations from first principles show that the wetting layer observed on Ru(0001) cannot be formed of undissociated water molecules. An energetically fa...
  8. Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels.

    Science 295(5552):143 (2002) PMID 11778053

    Hippocampal mossy fiber long-term potentiation (LTP) is expressed presynaptically, but the exact mechanisms remain unknown. Here, we demonstrate the involvement of the hyperpolarization-activated cation channel (Ih) in the expression of mossy fiber LTP. Established LTP was blocked and reversed b...
  9. Fluorescent signaling in parrots.

    Science 295(5552):92 (2002) PMID 11778040

  10. Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.

    Science 295(5552):120 (2002) PMID 11778046

    The isoprenylated benzoquinone coenzyme Q is a redox-active lipid essential for electron transport in aerobic respiration. Here, we show that withdrawal of coenzyme Q (Q) from the diet of wild-type nematodes extends adult life-span by approximately 60%. The longevity of clk-1, daf-2, daf-12, and...
  11. The quest for population III.

    Science 295(5552):66 (2002) PMID 11778036

  12. Clustered star formation and the origin of stellar masses.

    Science 295(5552):68 (2002) PMID 11778037

    Star clusters are ubiquitous in galaxies of all types and at all stages of their evolution. We also observe them to be forming in a wide variety of environments, ranging from nearby giant molecular clouds to the supergiant molecular clouds found in starburst and merging galaxies. The typical sta...
  13. The formation of the first star in the Universe.

    Science 295(5552):93 (2002) PMID 11711636

    We describe results from a fully self-consistent three-dimensional hydrodynamical simulation of the formation of one of the first stars in the Universe. In current models of structure formation, dark matter initially dominates, and pregalactic objects form because of gravitational instability fr...
  14. Solar system exploration. Tight budget makes for an uncertain future.

    Science 295(5552):38 (2002) PMID 11778025

  15. Combined functional genomic maps of the C. elegans DNA damage response.

    Science 295(5552):127 (2002) PMID 11778048

    Many human cancers originate from defects in the DNA damage response (DDR). Although much is known about this process, it is likely that additional DDR genes remain to be discovered. To identify such genes, we used a strategy that combines protein-protein interaction mapping and large-scale phen...
  16. Fluorescent signaling in parrots.

    Science 295(5552):92 (2002) PMID 11778040

  17. Geophysics. Caught offside.

    Science 295(5552):55 (2002) PMID 11778031

  18. The runts of the cosmic litter.

    Science 295(5552):64 (2002) PMID 11778035

  19. The initial mass function of stars: evidence for uniformity in variable systems.

    Science 295(5552):82 (2002) PMID 11778039

    The distribution of stellar masses that form in one star formation event in a given volume of space is called the initial mass function (IMF). The IMF has been estimated from low-mass brown dwarfs to very massive stars. Combining IMF estimates for different populations in which the stars can be ...
  20. Construction and analysis of a human-chimpanzee comparative clone map.

    Science 295(5552):131 (2002) PMID 11778049

    The recently released human genome sequences provide us with reference data to conduct comparative genomic research on primates, which will be important to understand what genetic information makes us human. Here we present a first-generation human-chimpanzee comparative genome map and its initi...