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- Ama, CSA, Endocrine, Rupress, Csh, Aacr, Gale, Highwire, Aaas, Proquest, Jstor, Ovid, and Nephrology
Predation risk affects reproductive physiology and demography of elk.
Elk (Cervus elaphus) in the Greater Yellowstone Ecosystem alter patterns of aggregation, habitat selection, vigilance, and foraging in the presence of wolves (Canis lupus). Antipredator behaviors like these can reduce predation risk but are also likely to carry costs. Data from five elk populations...
Ocean acidification foils chemical signals.
Helping robots see the big picture.
Photochemistry. Hot molecules--off the beaten path.
Marine geophysics. New global marine gravity model from CryoSat-2 and Jason-1 reveals buried tectonic structure.
We combined new radar altimeter measurements from satellites CryoSat-2 and Jason-1 with existing data to construct a global marine gravity model that is two times more accurate than previous models. We found an extinct spreading ridge in the Gulf of Mexico, a major propagating rift in the South Atla...
Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.
We analyzed changes in the ubiquitin landscape induced by prostate cancer-associated mutations of SPOP, an E3 ubiquitin ligase substrate-binding protein. SPOP mutants impaired ubiquitylation of a subset of proteins in a dominant-negative fashion. Of these, DEK and TRIM24 emerged as effector substrat...
Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4.
We identified germline heterozygous mutations in CTLA4 in subjects with severe immune dysregulation from four unrelated families. Whereas Ctla4 heterozygous mice have no obvious phenotype, human CTLA4 haploinsufficiency caused dysregulation of FoxP3(+) regulatory T (Treg) cells, hyperactivation of e...
Intense foreshocks and a slow slip event preceded the 2014 Iquique Mw 8.1 earthquake.
We studied the location and mechanisms of the foreshocks and computed Global Positioning System (GPS) time series at stations located on shore. Seismicity off the coast of Iquique started to increase in January 2014. After 16 March, several Mw > 6 events occurred near the low-coupled zone. These eve...
Neuroscience. Astrocytes eyeball axonal mitochondria.
This Week's Section.