Compte rendu des seances de la Societe de Biologie, Paris. Paris
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[Effect of modafinil on electroretinograms of Lycosa tarentula in relation visual circadian rhythm (Araneae, Lycosidae)].
These results are discussed in relation to the visual activity of this species, both diurnal and nocturnal. The concepts of waking state versus sleep are not precisely characterized in arachnids, so that the effects of modafinil on L. tarentula may not be considered like those described in vertebrat...
[Strategy for identification of new neuropeptides].
Neuropeptides play a crucial role in cell communication as neurotransmitters, neuromodulators or neurohormones, and are involved in a number of biological activities including neuroendocrine regulations, control of neurovegetative functions, trophic effects and modulation of the immune response. The...
[Synthesis of novel fructo-oligosaccharides (FOS) by enzymatic reaction].
Our FOS were identified by both HPLC and 13C-NMR spectrometry as neo-FOS type (neo-kestose, neo-nystose and neo-fructofuranosylnystose), a new structure which is very close to inulin type (same linkage between fructosyl units). The neo-FOS may act as a prebiotic factor due to their structural simila...
[Identification of NPDC-1, gene involved in the control of proliferation and differentiation of neural and glial precursors].
We used was to search for cDNAs which both hybridized with helix-loop-helix degenerated probes and corresponded to RNAs expressed preferentially when neural precursor cells become growth-arrested and began to differentiate. This led to the isolation of NPDC-1 cDNA and then of the genomic sequence. W...
[Aging and brain circulation. Role of the extracellular matrix of brain microvessels].
Maintenance of normal brain activity is dependent among other factors on the maintenance of a functional blood-brain barrier (BBB), localised mainly at the capillary wall of cerebral microcirculation. The modifications of the BBB during aging play an important role in cognitive decline with aging as...
[In vivo and in vitro study of the effect of somatostatin and somatostatin-immunoreactive substance on the histology of the mantle edge in a...
These results suggest that they could regulate the growth and the repair of the shell and that the mantle edge gland might be considered as one of their tissue targets....
[Genetic control of rhombencephalon development by Hox genes studied in bird embryo by the quail-chick chimera method].
We took advantage of the quail/chick chimera system to study the regulation of Hox gene expression in neural tube and neural crest cells. We have therefore ectopically transplanted the presumptive territories of the future rhombomeres and studied the evolution of their Hox code. We evidence in the p...
[Development of adenoviral vectors in gene therapy: application to gene transfer in muscles].
We summarize our results of gene transfer in mice. We have evaluated efficiency of systemic and intramuscular injections, the impact of age at injection, the duration of expression in adult normal and genetically-immunosuppressed SCID mice, using a recombinant adenovirus expressing a reporter gene....
[The important role of apolipoprotein C-III in lipoprotein metabolism].
Apolipoprotein C-III (apo C-III) is present in the plasma in apo B containing lipoprotein (apo C-III-LpB) and in non apo B containing lipoprotein (apo C-III-Lp non B). Apo C-III inhibits the lipolysis of triglyceride riche particles and the apo B containing lipoprotein binding to the LDL receptor. A...
[Evolution of breathing pattern and ventilation at maximal exercise during growth. Definition of reference values].
We observed that the peak height velocity and peak tidal volume velocity took place at the same age, i.e., 14 years and that those of weight and VT/TI at the same age of 15 years. In conclusion, this study allowed us to define reference values for breathing pattern at maximal exercise in sedentary b...