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[Successful use of vemurafenib in a patient with resistant hairy cell leukemia].
The paper describes a case of a patient with refractory hairy cell leukemia. In spite of the absence of CD25 expression, the disease was classified as a classical form according to the WHO classification (2008), as also confirmed by the detection of BRAFV600E mutation. The disease was characterized...
[Gene expression of vascular endothelial growth factors and their receptors in different variants of the course of multiple myeloma].
To determine the significance of the angiogenic activity estimated from the gene expression of the vascular endothelial growth factors (VEGFs) VEGF-A, VEGF-C, and VEGF-D and their receptors VEGFR1, VEGFRls, VEGFR2, and VEGFR3 in the mononuclear cell fraction of bone marrow (BM) aspirates with tumor...
[Determination of the scope of cerebral stroke and myocardial infarction rehabilitation in accordance with the International Classification ...
To determine the scope of rehabilitation in the evaluation of activity limitations and participation restrictions in patients with cerebral stroke in accordance with the International Classification of Functioning, Disability, and Health (ICF) and to compare the findings with respective disorders in...
[Clinical characteristics of dyspepsia in patients with diabetes mellitus type 2].
To estimate the prevalence of dyspepsia and to study its clinical manifestations and risk factors in patients with type 2 diabetes mellitus. One hundred and seven patients with type 2 DM and 33 with functional dyspepsia were examined. A clinical and laboratory study and testing were made to identify...
[Experience with ebrantil used in patients with resistant arterial hypertension in chronic kidney disease].
To evaluate the clinical efficacy of ebrantil used in patients with resistant arterial hypertension (RAH) in Stage III-V chronic kidney disease (CKD). Sixty-five patients with Stage III-V CKD and RAH (systolic blood pressure (SBP) 215.7 +/- 4.0 mm Hg and diastolic blo...
[The role of day hospital in optimization of medical care for patients of a therapeutic department of an outpatient clinic].
Day hospital (DH) provides consultations and treatment for all referred patients according to standards of medical care quality. DH has facilities for therapeutic and gastroenterological patients. Treatment in DH is performed according to current standards which cover basic treatment...
[From classification medicine to clinical medicine (the end of the XVIII century--1870s) communication 5. Reforms in therapy in 1840s-1860s]...
Reforms of therapy in 1840-1860s are considered: development of the methods of objective assessment of efficacy of some methods of treatment, appearance of experimental pharmacology, introduction of anasthesia.
[Choice of treatment of patients with arterial hypertension: symptomatic and basic, standard and situational].
The article analyses cardiovascular morbidity and mortality with consideration of arterial hypertension (AH) involvement in terms of pathogenesis, chronicity of AH and its complications, causes of target organs affection. Such methods of treatment as symptomatic, basic, standard and...
[The XI Congress of the Russian Gastroenterological Society, the XXXVII session of the Central Research Institute of Gastroenterology].
[Treatment of acute host-versus-graft reaction in patients after allogeneic hematopoietic cell transplantation with multipotent mesenchymal ...
To evaluate the efficiency of administration of multipotent mesenchymal stromal cells obtained from a bone marrow donor for the treatment of an acute host-versus-graft reaction (HVGR) resistant to therapy with glucocorticosteroids (GCS). The experience in treating 6 patients with GCS-resistant acute...