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Human Pathology

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  1. Editorial Board
    Author(s) unavailable

    Human Pathology 46(5):iii (2015)

  2. In This Issue
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    Human Pathology 46(5):iv (2015)

  3. Immunohistochemical expression of ARID1A in penile squamous cell carcinomas: a tissue microarray study of 112 cases

    Human Pathology 46(5):761 (2015) PMID 25776029

    ARID1A, a member of the chromatin remodeling genes family, has been suggested as a novel tumor suppressor gene in gynecologic malignancies. However, its role in penile cancer has yet to be determined. This study assesses the immunohistochemical expression of ARID1A in penile squamous c...
  4. Table of Contents
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    Human Pathology 46(5):i (2015)

  5. Masthead
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    Human Pathology 46(5):IFC (2015)

  6. HER2 status in gastroesophageal cancer: a tissue microarray study of 1040 cases

    Human Pathology 46(5):665 (2015) PMID 25800719

    Among patients with gastric cancer (GC) and gastroesophageal cancer (G-EC), HER2 amplification identifies those who may benefit from trastuzumab. HER2 status assessment, however, is influenced by preanalytic, analytic, and postanalytic variables. In a series of 5426 microarray cancer t...
  7. Immunohistochemical analysis of the expression of cellular transcription NFκB (p65), AP-1 (c-Fos and c-Jun), and JAK/STAT in leprosy

    Human Pathology 46(5):746 (2015) PMID 25771902

    Leprosy is a disease whose clinical spectrum depends on the cytokine patterns produced during the early stages of the immune response. The main objective of this study was to describe the activation pattern of cellular transcription factors and to correlate these factors with the clini...
  8. Profilin-1 expression is associated with high grade and stage and decreased disease-free survival in renal cell carcinoma

    Human Pathology 46(5):673 (2015) PMID 25704627

    Clear cell renal cell carcinoma (ccRCC) is associated with high mortality, although individual outcomes are highly variable. Identification of patients with increased risk of disease progression can guide customizing management plan according to disease severity. Profilin-1 (Pfn1) has ...
  9. Automatic quantification of lobular inflammation and hepatocyte ballooning in nonalcoholic fatty liver disease liver biopsies

    Human Pathology 46(5):767 (2015) PMID 25776030

    Automatic quantification of cardinal histologic features of nonalcoholic fatty liver disease (NAFLD) may reduce human variability and allow continuous rather than semiquantitative assessment of injury. We recently developed an automated classifier that can detect and quantify macrostea...
  10. Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma

    Human Pathology 46(4):554 (2015) PMID 25656929

    Small cell carcinoma (SmCC) of the prostate is a rare and aggressive histologic subtype of the prostate cancer. It can sometimes mimic acinar adenocarcinoma with a high Gleason score (GS). A previous study showed that immunohistochemical staining for CD44 could help in the differential...