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Case report of extensive metabolism by aldehyde oxidase in humans: Pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and huma...
X-ray diffraction with synchrotron radiation has been used for the first time to study chemical interaction in the MnO-ZnO system at 4.8 GPa and temperatures up to 1600 K. Above 750 K, the chemical reaction between MnO and ZnO has been observed that resulted in the formation of rock salt (rs) Mn1-x...
Biological fate of sulphur mustard in rat: toxicokinetics and disposition.
1. The toxicokinetics of sulphur mustard were studied after i.v. administration (10mg/kg) to rat. 2. After i.v. administration, blood concentrations of sulphur mustard were best described by a two-compartment model with distribution and elimination half-lives of 5-6 min and 3-59 h, respectively. The...
Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone
Differences in the metabolism and pharmacokinetics of two structurally similar PPAR agonists in dogs: involvement of taurine conjugation
Characterization of moclobemide N-oxidation in human liver microsomes
Regioselective hydroxylation of debrisoquine by cytochrome P4502D6: implications for active site modelling
Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1
Elimination of methoxyacetic acid and ethoxyacetic acid in rat
Human moricizine metabolism. II. Quantification and pharmacokinetics of plasma and urinary metabolites
An ab initio approach to the understanding of cytochrome P450-ligand interactions