Advances in Experimental Medicine and Biology

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0065-2598
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1.379
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Proquest
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10852
Article count
29026
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16
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0.00055123
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CSA and Proquest

  1. Soluble ligand CD40 and uric acid as markers of atheromatosis in patients with obstructive sleep apnea.

    Advances in Experimental Medicine and Biology 839:55 (2015) PMID 25315617

    The aim of the study was to evaluate the risk of atheromatosis in patients with obstructive sleep apnea (OSA), as based on the concentration of the pro-atherogenic soluble CD40L ligand (sCD40L) in relation to the level of uric acid. The serum levels of sCD40L and uric acid were measured in 79 OS...
  2. Markers of bone metabolism in children with nephrotic syndrome treated with corticosteroids.

    Advances in Experimental Medicine and Biology 840:21 (2015) PMID 25310960

    The aim of the study was to assess bone mineral density, bone metabolism markers, and vitamin D level in children with idiopathic nephrotic syndrome in the course of 1-year observation. Twenty five children with nephrotic syndrome aged 5-17 years were enrolled into the study. The median number o...
  3. Alcohol metabolism by oral streptococci and interaction with human papillomavirus leads to malignant transformation of oral keratinocytes.

    Advances in Experimental Medicine and Biology 815:239 (2015) PMID 25427911

    Poor oral hygiene, ethanol consumption, and human papillomavirus (HPV) are associated with oral and esophageal cancers. However, the mechanism is not fully known. This study examines alcohol metabolism in Streptococcus and its interaction with HPV-16 in the malignant transformation of oral kerat...
  4. Alcohol, carcinoembryonic antigen processing and colorectal liver metastases.

    Advances in Experimental Medicine and Biology 815:295 (2015) PMID 25427914

    It is well established that alcohol consumption is related to the development of alcoholic liver disease. Additionally, it is appreciated that other major health issues are associated with alcohol abuse, including colorectal cancer (CRC) and its metastatic growth to the liver. Although a correla...
  5. Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers.

    Advances in Experimental Medicine and Biology 815:265 (2015) PMID 25427912

    Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) modulate exposure levels to ethanol/acetaldehyde. Endoscopic screening of 6,014 Japanese alcoholics yielded high detection rates of esophageal squamous cell carcinoma (SCC; 4.1%) and head and neck SCC ...
  6. Metabolic and immunological consequences of vitamin D deficiency in obese children.

    Advances in Experimental Medicine and Biology 840:13 (2015) PMID 25315624

    Numerous studies highlighted the link between vitamin D deficiency and cardiovascular, autoimmune, metabolic diseases, and obesity. However, a clear role of vitamin D in these disorders is still unknown. Vitamin D deficiency in children can be a potential risk factor for developing diseases at a...
  7. Sodium and copeptin levels in children with community acquired pneumonia.

    Advances in Experimental Medicine and Biology 835:31 (2015) PMID 25252899

    Copeptin has been associated with the severity of pneumonia and its complications. This study was designed to assess the usefulness of copeptin measurement in children with community-acquired pneumonia (CAP) and copeptin's relation with disease severity and sodium equilibrium. The study encompas...
  8. Does customer information fulfill MEDDEV criteria in cases of product problems of in vitro diagnostics for infection testing?

    Advances in Experimental Medicine and Biology 835:23 (2015) PMID 25310946

    The European Directive 98/79/EC on in vitro diagnostics (IVD) regulates marketing and post market surveillance of IVD in the European Economic Area. In cases of incidents and field safety corrective actions (FSCA) manufacturers have to inform responsible competent authority (CA) and public by fi...
  9. Respiratory tract infections in children in primary healthcare in Poland.

    Advances in Experimental Medicine and Biology 835:53 (2015) PMID 25252897

    Respiratory tract infections are the most common diseases in children. The aim of the study was to assess their frequency and antibiotic treatment in Poland. We retrospectively analyzed 91 randomly-selected children aged 0-17 years receiving care from birth in a large primary healthcare establis...
  10. Variations of human urinary proteome.

    Advances in Experimental Medicine and Biology 845:91 (2015) PMID 25355572

    The study on dynamic analysis of human urinary proteome is the foundation that we discriminate certain various urinary proteins as potential bio-marker derived from the disease itself or normal physiological change. In our results, based on RPLC-MS/MS and spectral count to study pooled and indiv...
  11. Effects of diuretics on urinary proteins.

    Advances in Experimental Medicine and Biology 845:133 (2015) PMID 25355576

    Biomarker is the measurable change associated with a physiological or pathophysiological process. Unlike blood which has mechanisms to keep the internal environment homeostatic, urine is more likely to reflect changes of the body. As a result, urine is likely to be a better biomarker source than...
  12. Applications of urinary proteomics in renal disease research using animal models.

    Advances in Experimental Medicine and Biology 845:145 (2015) PMID 25355577

    Animal models of renal disease are essential tools in research on kidney disease and have provided valuable insights into pathogenesis. Use of animal models minimises inter-individual differences, allows specific pathological changes to be examined, and facilitates collection of tissue samples. ...
  13. Comparing plasma and urinary proteomes to understand kidney function.

    Advances in Experimental Medicine and Biology 845:187 (2015) PMID 25355581

    Kidney function is rarely studied in the context of blood kidney and urine as a system. Kidney can be considered as a black box, while plasma and urine proteomes closely represent the protein compositions of the input and output of the kidney. This idea provides a new approach for studying organ...
  14. Biofilm-based central line-associated bloodstream infections.

    Advances in Experimental Medicine and Biology 830:157 (2015) PMID 25366227

    Different types of central venous catheters (CVCs) have been used in clinical practice to improve the quality of life of chronically and critically ill patients. Unfortunately, indwelling devices are usually associated with microbial biofilms and eventually lead to catheter-related bloodstream i...
  15. Biofilm-based implant infections in orthopaedics.

    Advances in Experimental Medicine and Biology 830:29 (2015) PMID 25366219

    The demand for joint replacement surgery is continuously increasing with rising costs for hospitals and healthcare systems. Staphylococci are the most prevalent etiological agents of orthopedic infections. After an initial adhesin-mediated implant colonization, Staphylococcus aureus and Staphylo...
  16. Visual analytics of signalling pathways using time profiles.

    Advances in Experimental Medicine and Biology 823:3 (2015) PMID 25381099

    Data visualisation is usually a crucial first step in analysing and exploring large-scale complex data. The visualisation of proteomics time-course data on post-translational modifications presents a particular challenge that is largely unmet by existing tools and methods. To this end, we presen...
  17. Development of a motion capturing and load analyzing system for caregivers aiding a patient to sit up in bed.

    Advances in Experimental Medicine and Biology 823:127 (2015) PMID 25381105

    This research was carried out to analyze the actions of caregivers when aiding a patient to sit up in bed. The new system showed that three dimensional analysis could be performed even on points on the subjects' bodies that were hidden from view. We also developed a method to estimate the load o...
  18. Cloud based toolbox for image analysis, processing and reconstruction tasks.

    Advances in Experimental Medicine and Biology 823:191 (2015) PMID 25381109

    This chapter describes a novel way of carrying out image analysis, reconstruction and processing tasks using cloud based service provided on the Australian National eResearch Collaboration Tools and Resources (NeCTAR) infrastructure. The toolbox allows users free access to a wide range of useful...
  19. Stochastic anomaly detection in eye-tracking data for quantification of motor symptoms in Parkinson's disease.

    Advances in Experimental Medicine and Biology 823:63 (2015) PMID 25381102

    Two methods for distinguishing between healthy controls and patients diagnosed with Parkinson's disease by means of recorded smooth pursuit eye movements are presented and evaluated. Both methods are based on the principles of stochastic anomaly detection and make use of orthogonal series approx...
  20. Genetic Polymorphisms of Alcohol Dehydrogense-1B and Aldehyde Dehydrogenase-2, Alcohol Flushing, Mean Corpuscular Volume, and Aerodigestive Tract Neoplasia in Japanese Drinkers.

    Advances in Experimental Medicine and Biology 815:265 (2015) PMID 25427912

    Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) modulate exposure levels to ethanol/acetaldehyde. Endoscopic screening of 6,014 Japanese alcoholics yielded high detection rates of esophageal squamous cell carcinoma (SCC; 4.1 %) and head and neck SCC...