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Annals of the New York Academy of Sciences

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CSA, Gale, Ebscoatoz, Ebsconet, Ingenta, Wiley from 1879, Proquest, Ovid from 1038, and Rcgp

  1. Aging, diabetes, and renal failure catalyze the oxidation of lysyl residues to 2-aminoadipic acid in human skin collagen: evidence for metal-catalyzed oxidation mediated by alpha-dicarbonyls.

    Annals of the New York Academy of Sciences 1126:205 (2008) PMID 18448817

    The epsilon-amino group of lysyl residues oxidatively deaminates in the presence of alpha-dicarbonyl sugars and redox-active metals forming alpha-aminoadipic acid-delta-semialdehyde (allysine; Suyama's hypothesis), which can further oxidize into 2-aminoadipic acid. Here we show that 2-aminoadipi...
  2. alpha-Dicarbonyl compounds--key intermediates for the formation of carbohydrate-based melanoidins.

    Annals of the New York Academy of Sciences 1126:210 (2008) PMID 18448818

    The Maillard reaction of carbohydrates and amino acids is the chemical basis for flavor and color formation in many processed foods. Dicarbonyl compounds, such as 1-, 3-deoxyosones and 1,4-dideoxyosones, as well as short-chain dicarbonyls, such as methylgyoxal or glyoxal, are key compounds of th...
  3. Endometriosis and tissue factor.

    Annals of the New York Academy of Sciences 1127:101 (2008) PMID 18443336 PMCID PMC3129033

    Tissue factor (TF), is a cellular receptor that binds the ligand factor VII/VIIa to initiate the blood coagulation cascade. In addition to its role as the initiator of the hemostatic cascade, TF is known to be involved in angiogenesis via an interaction with factor VIIa and protease-activated re...
  4. Strategies for risk communication: evolution, evidence, experience.

    Annals of the New York Academy of Sciences 1128:ix (2008) PMID 18469207

    This volume presents the proceedings of the symposium entitled Strategies for Risk Communication: Evolution, Evidence, Experience. The symposium was held in Montauk, Long Island, New York on May 15-17, 2006. It explored practical methods and robust theories of risk communication informed by rece...
  5. Determination of N epsilon-(carboxymethyl)lysine in foods and related systems.

    Annals of the New York Academy of Sciences 1126:20 (2008) PMID 18448791

    The sensitive and specific determination of advanced glycation end products (AGEs) is of considerable interest because these compounds have been associated with pro-oxidative and proinflammatory effects in vivo. AGEs form when carbonyl compounds, such as glucose and its oxidation products, glyox...
  6. A novel yellow pigment, furpipate, derived from lysine and furfural.

    Annals of the New York Academy of Sciences 1126:307 (2008) PMID 18448836

    Furfural is an important intermediate compound of the Maillard reaction of pentose or ascorbic acid. We examined the browning of furfural and lysine by heating these compounds in solution and found two yellow compounds. The first, furpipate, is a novel pipecolic acid derivative and was (Z)-3-(2-...
  7. Analysis of amadori peptides enriched by boronic acid affinity chromatography.

    Annals of the New York Academy of Sciences 1126:253 (2008) PMID 18448825

    Glycation of peptides and proteins by D-glucose is a universal, nonenzymatic reaction with important implications for the pathogenesis and diagnosis of many diseases, including diabetes mellitus. Whereas some modification sites have been identified in serum albumin and hemoglobin, a general appr...
  8. Stem cells: a perspective on oocytes.

    Annals of the New York Academy of Sciences 1127:20 (2008) PMID 18443325

    Stem cells, with their unlimited self-renewal feature and their ability to differentiate into almost every mature cell type in the body, have enormous potential for research and therapeutic application. In this article, we review the formation of primordial germ cells, the precursors of adult ga...
  9. Visualizing seismic risk and uncertainty: a review of related research.

    Annals of the New York Academy of Sciences 1128:29 (2008) PMID 18469212

    Government agencies and other authorities often communicate earthquake risks using maps derived from geographic information systems. Yet, little is known about the effects of these maps on risk perceptions. While mental models research and other approaches are available to inform risk communicat...
  10. Oxidative stress and advanced glycation in diabetic nephropathy.

    Annals of the New York Academy of Sciences 1126:190 (2008) PMID 18448815

    Nephropathy remains a significant cause of morbidity and mortality in the diabetic population and is the leading cause of end-stage renal failure in the Western World. As a result of the diabetic milieu, increased generation of reactive oxygen species (ROS) is thought to play a key role in the p...