Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
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Psychosocial impact of cancer.
Diagnosis and treatment of malignant diseases affect in many ways the lives of patients, relatives and friends. In this chapter, we summarise the current knowledge concerning the psychosocial consequences of cancer.
Prevention of hepatitis C virus infection and liver cancer.
Recent results in cancer research. Fortschritte... 193:113 (2014) PMID 24008296Hepatocellular carcinoma (HCC) is the fifth most prevalent cancer and the third leading cause of cancer-related death, and its incidence is increasing. The majority of HCC cases are associated with chronic viral hepatitis. With over 170 million individuals chronically infected with hepatitis C virus...
Prevention of human T-cell lymphotropic virus type 1 infection and adult T-cell leukemia/lymphoma.
Recent results in cancer research. Fortschritte... 193:211 (2014) PMID 24008301Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive peripheral T-cell malignancy that develops after long-term chronic infection with human T-cell lymphotropic virus type-1 (HTLV-1). Despite the recent advances in chemotherapy, allogeneic hematopoietic stem cell transplantation (alloHSCT),...
Image-guided ablation for hepatocellular carcinoma.
Recent results in cancer research. Fortschritte... 190:181 (2013) PMID 22941021Image-guided ablation is accepted as the best therapeutic choice for patients with early-stage hepatocellular carcinoma (HCC) when surgical options-including resection and transplantation-are precluded. The term image-guided tumor ablation is defined as the direct application of chemical substances...
Multidisciplinary management of hepatocellular carcinoma.
Recent results in cancer research. Fortschritte... 190:247 (2013) PMID 22941025Treatment of HCC is complicated by its highly variable biologic behavior and the frequent coexistence of chronic liver disease and cirrhosis in affected patients. While surgery remains the most frequently employed treatment modality, curative resection is only possible for a minority of patients. Mo...
Mechanistic aspects of COX-2 expression in colorectal neoplasia.
We discuss novel insights in the mechanisms of altered post-transcriptional regulation of COX-2 in CRC and how this knowledge may be used to develop novel strategies for cancer prevention and treatment....
Endoscopic treatment for esophageal squamous cell carcinoma.
Recent results in cancer research. Fortschritte... 196:143 (2012) PMID 23129371
Prediction of Response and Prognosis by a Score Including only Pretherapeutic Parameters in 410 Neoadjuvant Treated Gastric Cancer Patients.
Recent results in cancer research. Fortschritte... 196:269 (2012) PMID 23129380Response to neoadjuvant chemotherapy (NAC) is an independent prognostic factor in locally advanced gastric cancer. However, no prospectively tested pretherapeutic parameters predicting response and/or survival in gastric cancer are available in clinical routine. Patients and methods: We evaluated th...
Perspectives in the elderly patient: benefits and limits of bisphosphonates and denosumab.
Recent results in cancer research. Fortschritte... 192:171 (2012) PMID 22307375We will discuss on pharmacokinetic and pharmacodynamic interactions of bisphosphonates in elderly, and the preclinical and clinical evidences of anticancer activity of bone-targeted therapies will be critically described. The clinical results of new targeted therapies (such as rank/rankl/OPG inhibit...
Helicobacter pylori and gastric cancer.
Gastric cancer remains a major cause of cancer death worldwide. The discovery of Helicobacter pylori Helicobacter pylori and its association with gastric cancer has opened up new insights into its pathogenesis. Gastric cancer pathogenesis is the result of a complex interplay between bacterial, host a...