Urologic Clinics of North America
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Office-based Management of Nonmuscle Invasive Bladder Cancer.
Bladder cancer is extremely common in the United States and extremely costly because of the high cost of surveillance. In some patients, office-based surveillance may be a safe, cost-reducing alternative. This article attempts to identify ideal candidates and highlights surveillance strategies that...
NMIBC risk calculators: how useful are they for the practicing urologist and how can their clinical utility be improved?
The natural history of non-muscle invasive bladder cancer (NMIBC) in individual patients can be unpredictable. Although there are known clinical and molecular factors associated with tumor recurrence and progression, it is challenging to reconcile these data during a typical patient encounter within...
Optimal risk-adapted surveillance strategies for NMIBC, including upper tract imaging.
Non-muscle invasive bladder cancer (NMIBC) represents approximately 70% of all incident cases of bladder cancer. The financial burden of NMIBC continues to increase, underscoring the importance of efficient, evidence-based management of this disease. Consensus guidelines differ on risk definition an...
New insights into the pathogenesis of renal calculi.
The pathophysiology of the various forms of urinary stone disease remains a complex topic. Epidemiologic research and the study of urine and serum chemistries have created an abundance of data to help drive the formulation of pathophysiologic theories. This article addresses the associations of urin...
Role of autologous bladder-neck slings: a urogynecology perspective.
The concept of the autologous pubovaginal sling involves supporting the proximal urethra and bladder neck with a piece of graft material, achieving continence either by providing a direct compressive force on the urethra/bladder outlet or by reestablishing a reinforcing platform or h...
Central nervous system agents and erectile dysfunction.
Several centrally acting agents have shown potential to improve erectile function in men with ED. They still lack adequate data in efficacy and tolerability. Nasal formulations of apomorphine and bremelanotide seem to be the most likely candidates for future approval. They may play a...
Priapism: new concepts in medical and surgical management.
Advances have recently been made in both medical and surgical management of priapism, and these offer improvements in the level of care afforded such patients. Further developments can be expected based on ongoing progress, particularly in the area of molecular science, which is the...
Peyronie disease: plication or grafting.
Peyronie disease (PD) is an incurable, sexually debilitating disease resulting in penile deformity, coital failure, and significant psychological stress for patients and their partners. Appropriate treatment should be individualized and tailored to the patient's goals and expectation...
Pharmacologic therapy for the neurogenic bladder.
This article is a review of the current and past literature on medical management of the neurogenic bladder, with a particular focus on spinal cord injury and multiple sclerosis. The use of antimuscarinics, αα-blocker, and tricyclic antidepressants and their combined use are discussed along with...
Cryptorchidism: pathogenesis, diagnosis, treatment and prognosis.
Cryptorchidism is a common genital anomaly diagnosed at birth or during childhood. Genetic and/or environmental factors that alter expression or function of hormones crucial for testicular descent, insulin-like 3, and testosterone, may contribute to cryptorchidism. When identified at...