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Modeling the dosimetry of organ-at-risk in head and neck IMRT planning: An intertechnique and interinstitutional study.
The authors established a mathematical model to correlate the anatomical features and dosimetric indexes of OARs of HN patients in Tomotherapy plans. The model can be used for the setup of patient-specific OAR dose sparing goals and quality control of planning results.The institutional clinical expe...
Impact of the MLC on the MRI field distortion of a prototype MRI-linac.
This work shows that the MRI field distortions caused by the MLC cannot be ignored and must be thoroughly investigated for any MRI-linac system. The numeric distortion values obtained for our 1.0 T magnet may vary for other magnet designs with substantially different fringe fields, however the conce...
Predicting objective function weights from patient anatomy in prostate IMRT treatment planning.
This study demonstrates a proof of concept that patient anatomy can be used to predict appropriate objective function weights for treatment planning. In the long term, such geometry-driven weights may serve as a starting point for iterative treatment plan design or may provide information about the...
Resolution enhancement of lung 4D-CT via group-sparsity.
The authors have proposed to improve the superior-inferior resolution of 4D-CT by estimating intermediate slices. The authors' approach exploits neighboring constraints in the group-sparsity framework, toward the goal of achieving better localization and noise robustness. The authors' results are en...
A comprehensive investigation of the accuracy and reproducibility of a multitarget single isocenter VMAT radiosurgery technique.
The deliveries of the irradiation were found to be consistent and matched the treatment plan, demonstrating high accuracy and reproducibility of both the treatment machine and the IGRT procedure. The complexity of the treatment (multiple arcs) and dosimetry (multiple strong gradients) pose a substan...
Respiratory effort correction strategies to improve the reproducibility of lung expansion measurements.
All effort correction strategies improve the reproducibility of the authors' pulmonary ventilation measures, and the improvement of reproducibility is highly correlated with the changes in respiratory effort. ELV gives better results as effort difference increase, followed by ETV, then global. Howev...
Daily dose monitoring with atlas-based auto-segmentation on diagnostic quality CT for prostate cancer.
With patient specific 4-image atlases, atlas-based autosegmentation can adequately facilitate daily dose monitoring for prostate cancer....
Characteristics of flattening filter free beams at low monitor unit settings.
The characteristics of low-MU beams delivered in IM mode were evaluated using an automatic measurement system developed in this study. The authors demonstrated that the profiles of FFF beams of the Artiste™ linac were highly stable, even at low MU. The linearity of dose output was also stable for be...
International workshop on non-ionizing radiation protection in medicine.
An international workshop brought together a range of stakeholders to consider protection from non-ionizing radiation used in medicine, research and cosmetics. Presentations on specific topics were followed by a general discussion on possible improvements in protection. Participants considered that...
Optimization in interstitial plasmonic photothermal therapy for treatment planning.
Gold nanorods have the potential to enhance the treatment efficacy of interstitial photothermal therapy. In order to enhance both the potential efficiency and the safety of such procedures, treatment planning on laser power density, nanoparticle concentration, and exposure time has turned out to be...