Journal of Nuclear Medicine
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- Csh, Endocrine, Proquest, Ama, Nephrology, Highwire from 1964, Aaas, Rupress, CSA, and Aacr
The value of 99mTc-tetrofosmin brain SPECT in predicting survival in patients with glioblastoma multiforme.
By calculating the lesion-to-normal (L/N) (99m)Tc-tetrofosmin uptake ratio, we found that patients with an L/N ratio of more than 4.7 had significantly worse survival than did patients with an L/N ratio of 4.7 or less. Furthermore, patients with a Karnofsky Performance Score more than 90 had a signi...
In vivo assay of folate receptors in nonfunctional pituitary adenomas with 99mTc-folate SPECT/CT.
Integrated CT was useful for uptake localization and assisted region-of-interest placement. Qualitative interpretation of planar imaging yielded a sensitivity of 81% and specificity of 72%. Qualitative SPECT/CT yielded a sensitivity of 94% and specificity of 61%. Receiver-operating-characteristic cu...
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Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI.
An optimal registration of PET and MR images from the integrated system was achieved, and the reconstructed images showed a good visual correspondence in infarct areas between PET and MRI data. As expected, the PET insert showed a poorer performance with respect to counting rate and myocardium-to-ba...
Synthesis and preliminary evaluation of 18-(18)F-fluoro-4-thia-oleate as a PET probe of fatty acid oxidation.
A practical synthesis of (18)F-FTO was developed, providing a radiotracer of high radiochemical purity (>99%). In fasted rats, myocardial uptake of (18)F-FTO (0.70 +/- 0.30% dose kg [body mass]/g [tissue mass]) was similar to that of (18)F-FTP at 30 min after injection. At 2 h, myocardial uptake of...
Reply: 18F-FDG PET for Routine Posttreatment Surveillance in Oral and Oropharyngeal Squamous Cell Carcinoma
PET assessment of myocardial perfusion reserve inversely correlates with intravascular ultrasound findings in angiographically normal cardia...
In 27 angiographically normal cardiac transplant recipients, MBF at rest and during adenosine stress and MPR of the left anterior descending artery distribution correlated strongly with the other 2 coronary artery distribution territories (r >/= 0.97, P < 0.0001). Summed stress score and summed diff...
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Reply: Molecular Imaging of EGFR: It's Time to Go Beyond Receptor Expression