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Journal of Neuroscience Methods

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  1. A method for measuring brain partial pressure of oxygen in unanesthetized unrestrained subjects: the effect of acute and chronic hypoxia on ...

    Journal of Neuroscience Methods 193(2):217 (2010) PMID 20817029 PMCID PMC3044503

    We present a novel fiber optic method to measure brain PtO(2). This method can be used in unanesthetized, unrestrained animals, provides absolute values for PO(2), has a stable calibration, does not consume oxygen and is MRI compatible. Brain PtO(2) was studied during acute hypoxia, as well as befor...
  2. Assessing spatial vision - automated measurement of the contrast-sensitivity function in the hooded rat.

    Journal of Neuroscience Methods 97(2):103 (2000) PMID 10788664

    We therefore designed an economical and rapid method to assess the hooded rat's CSF, using a computer monitor to display stimuli and an infrared touch screen to record responses. A six-alternative forced-choice task presented trials in which a sine-wave grating (S+), varying in spatial frequency and...
  3. Independent component analyses for quantifying neuronal ensemble interactions.

    Journal of Neuroscience Methods 94(1):141 (1999) PMID 10638821

    We describe applications of principal component analysis (PCA) and independent component analysis (ICA) (Cardoso J-F, Souloumiac A. IEE-Proc F 1993;140:362-70; Hyvarinen A, Oja E. Neural Comput 1997;9:1483-92; Lee TW, Girolami M, Sejnowski TJ. Neural Comp 1999;11:417-41) to neuronal ensemble data. S...
  4. A simple analytical method for determining the steady-state potential in models of geometrically complex neurons.

    Journal of Neuroscience Methods 82(2):123 (1998) PMID 9700684

    A method is presented for solving the cable equation for a spiking neuron below firing threshold or a nonspiking neuron of arbitrary geometry under constant stimulation. The neuron structure is considered as a tree composed of a set of cylinder cables of three types (terminal, intermediate and branc...
  5. Electrically evoked compound action potentials artefact rejection by independent component analysis: Procedure automation

    Journal of Neuroscience Methods 239:85 (2015)

    • Electrically-evoked compound action potentials can be extracted from artefact using independent component analysis: this paper shows how to automate it. • Raw-ECAP r...
  6. Automated tracking and analysis of behavior in restrained insects

    Journal of Neuroscience Methods 239:194 (2015)

    We present an algorithm for tracking the movement body parts of restrained animals. • The tracking algorithm works with low frame-rate videos. • The tracking algorithm automati...
  7. Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice

    Journal of Neuroscience Methods 239:100 (2015)

    • Photothrombosis was induced in freely moving mice. • Neurobehavioral assessments of focal ischemia in a whole process....
  8. Apparatus for investigating the reactions of soft-bodied invertebrates to controlled humidity gradients.

    Journal of Neuroscience Methods 237:54 (2014) PMID 25176025

    We describe an easy-to-construct, low-cost humidity chamber to assay the behavior of small animals, including soft-bodied invertebrates, in controlled humidity gradients. We show that our humidity-chamber design is amenable to soft-bodied invertebrates and can produce reliable gradients ranging 0.3-...
  9. Sparse models for correlative and integrative analysis of imaging and genetic data.

    Journal of Neuroscience Methods 237:69 (2014) PMID 25218561 PMCID PMC4194220

    We review our recent work on developing sparse representation based approaches to address this challenge. We show how sparse models are applied to the correlation and integration of imaging and genetic data for biomarker identification. We present examples on how these approaches are used for the de...
  10. A real-time 3D video tracking system for monitoring primate groups.

    Journal of Neuroscience Methods 234:147 (2014) PMID 24875622

    We describe a real-time multi-camera 3D tracking system developed to measure the behavior of socially-housed primates. Their positions are identified using non-invasive color markers such as plastic collars, thus allowing to also track colored objects and to measure their usage. Compared to traditio...