Journal of Neuroscience Methods
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Towards an optimal paradigm for simultaneously recording cortical and brainstem auditory evoked potentials
Journal of Neuroscience Methods 241:94 (2015)• Present a new stimulus paradigm for concurrent recording of brainstem/cortical ERPs. • Clustered/variable stimulus presentation was optimized to reduce habituation....
Visualization of neurotransmitter uptake and release in serotonergic neurons
Journal of Neuroscience Methods 241:10 (2015)We have established the visualization of fluorescent transmitter-like substrates in stem cell-derived serotonergic neurons. • We have combined uptake and release of fluorescent substrates into and from serotonergic neurons with quantitati...
Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging
We present an open-source software for semi-automated analysis of fluorescent calcium imaging. • FluoroSNNAP, Fluorescence Single Neuron and Network Analysis Package, enables automated segmentation and calcium transient event detections....
Improving the use of principal component analysis to reduce physiological noise and motion artifacts to increase the sensitivity of task-bas...
Journal of Neuroscience Methods 241:18 (2015)
Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting.
We outline general physical and genetic approaches for macroglial cell generation. We summarize cell culture methods to obtain astrocytes and oligodendrocytes and their precursors, from developing and adult tissue, as well as approaches to obtain human neural progenitor cells through the establishme...
Burrowing and nest building behavior as indicators of well-being in mice.
The assessment of pain, distress and suffering, as well as evaluation of the efficacy of stress-reduction strategies, is crucial in animal experimentation but can be challenging in laboratory mice. Nest building and burrowing performance, observed in the home cage, have proved to be valuable and eas...
A wavelet based algorithm for the identification of oscillatory event-related potential components.
We demonstrate that the asymmetry method is more accurate than the matching wavelet algorithm and t-CWT method by 48.67 and 8.03 percent, respectively. This paper provides an off-line demonstration of the algorithm and considers issues related to the extension of the algorithm to real-time applicati...
Ballistocardiogram artifact removal with a reference layer and standard EEG cap.
In simultaneous EEG-fMRI, the EEG recordings are severely contaminated by ballistocardiogram (BCG) artifacts, which are caused by cardiac pulsations. To reconstruct and remove the BCG artifacts, one promising method is to measure the artifacts in the absence of EEG signal by placing a group of elect...
Sensory and cognitive neurophysiology in rats. Part 2: Validation and demonstration.
We have developed a novel setup for rats that allows for controlled sensory input to an animal engaged in a task while recording both electrophysiological signals and behavioral output. Our setup is described in a companion paper. We validate our setup by replicating (1) the functionally nonspecific...
Methods for pulse artefact reduction: experiences with EEG data recorded at 9.4 T static magnetic field.
We conducted a study in which different PA correction methods were applied to EEG data recorded inside a 9.4 T scanner in order to retrieve visual P100 and auditory P300 evoked potentials. We explored different PA reduction methods, including the optimal basis set (OBS) method as well as objective a...