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Veterinary Immunology and Immunopathology

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  1. Molecular cloning and characterization of interleukin-1β in half-smooth tongue sole Cynoglossus semilaevis.

    Veterinary Immunology and Immunopathology 146(3-4):270 (2012) PMID 22436375

    We reported the full length cDNA of IL-1β in half-smooth tongue sole (Cynoglossus semilaevis). The csIL-1β cDNA contained a 130bp 5' UTR, a 417bp 3' UTR and a 741bp coding sequence (CDS) that translated into a polypeptide of 246 amino acids. The protein sequence included a typical IL-1 family sign...
  2. Up-regulation by feline interleukin-4 and down-regulation by feline interferon-gamma of major histocompatibility complex class II on cat B-l...

    Veterinary Immunology and Immunopathology 88(3-4):197 (2002) PMID 12127417

    We show that IL-4 also has a regulatory function in the cat species. Cells transfected with IL-4 DNA expressed a biologically active protein as demonstrated by the up-regulation of MHC class II molecules on B-lymphocytes (CD21(+)) in a flow cytometric assay. Increased levels of MHC class II expressi...
  3. Candidate genes for resistance to Salmonella enteritidis colonization in chickens as detected in a novel genetic cross.

    Veterinary Immunology and Immunopathology 87(3-4):423 (2002) PMID 12072268

    Salmonellosis is a zoonotic disease that is problematic for both animal production and food safety. A novel genetic cross, named the Iowa Salmonella response resource population (ISRRP), was established to elucidate the genetic control of resistance to Salmonella enteritidis (SE) colonization in you...
  4. Localization of the sheep FcRn in the mammary gland.

    Veterinary Immunology and Immunopathology 87(3-4):327 (2002) PMID 12072253

    We study its role in the IgG transport in the mammary gland during the colostrum formation. For this reason, we have obtained several mammary gland biopsies from a pregnant sheep around parturition. The presence of the FcRn heavy chain mRNA was detected exclusively in the acinar and ductal epithelia...
  5. Intranasal peptide-induced peripheral tolerance: the role of IL-10 in regulatory T cell function within the context of experimental autoimmu...

    Veterinary Immunology and Immunopathology 87(3-4):357 (2002) PMID 12072259

    Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune disease commonly employed as a model for multiple sclerosis. Extensive studies have demonstrated that EAE may be prevented or ameliorated by the intranasal administration of soluble peptides representing encephalitogenic...
  6. The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy.

    Veterinary Immunology and Immunopathology 81(3-4):311 (2001) PMID 11553393

    The treatment of canine atopic dermatitis is multifaceted and consists of a combination of actions that include the use of allergen avoidance, anti-inflammatory agents, allergen-specific immunotherapy and antimicrobial drugs. The importance and order of these treatment steps vary from patient to pat...
  7. Genetic characterisation of protective vaccine responses in sheep using multi-valent Dichelobacter nodosus vaccines.

    Veterinary Immunology and Immunopathology 72(1-2):219 (1999) PMID 10614512

    We examined the importance of genetic polymorphism within the ovine MHC, and the possibility of genes outside the MHC for their involvement in antigen-specific and broad-based vaccine response. Within two large half sib families(131, and 143 progeny), four MHC haplotypes were investigated and found...
  8. Developments in international standardization.

    Veterinary Immunology and Immunopathology 72(1-2):243 (1999) PMID 10614515

    Trade in animals and animal products has reached global proportions and so too has the threat of infectious diseases of veterinary importance. The Manual of Standards for Diagnostic Tests and Vaccines, published by the Office International des Epizooties (OIE), contains chapters on infectious diseas...
  9. Interaction between Salmonella typhimurium and phagocytic cells in pigs. Phagocytosis, oxidative burst and killing in polymorphonuclear leuk...

    Veterinary Immunology and Immunopathology 67(3):259 (1999) PMID 10195464

    Interactions between Salmonella typhimurium and peripheral blood leucocytes from healthy, Salmonella-free pigs were investigated in vitro. Both granulocytes and monocytes phagocytized FITC-labelled heat-killed Salmonella bacteria as shown by flow cytometry. Phagocytosis in whole blood and isolated l...
  10. Evidence of reproductive failure and lack of perinatal transmission of Bartonella henselae in experimentally infected cats.

    Veterinary Immunology and Immunopathology 65(2-4):177 (1998) PMID 9839873

    Five female specific pathogen-free (SPF) cats inoculated intradermally with B. henselae and bacteremic for 4 weeks, and one cat inoculated with 0.9% NaCl, were bred with uninfected SPF male cats. The uninfected female became pregnant with one breeding, while three infected cats became pregnant 1-12...