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Veterinary Immunology and Immunopathology

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  1. CD45 + and CD45- lymphocyte populations identified by flow cytometry from dogs with lymphoma exhibit similar morphology and the same clonal (B cell or T cell) lineage

    Veterinary Immunology and Immunopathology (2015)

    • CD45+and CD45- cells were identified by flow cytometry in canine lymphoma • CD45+and CD45- cells were sorted using high speed cell sorting ...
  2. Development of an In vitro Model of the Early-Stage Bovine Tuberculous Granuloma using Mycobacterium bovis-BCG

    Veterinary Immunology and Immunopathology (2015)

    • We have developed an early-stage bovine tuberculous granuloma model in vitro. • M.bovis-BCG infected-MDM and lymphocytes formed 3D spherical-shape aggregations. ...
  3. Characterizing the thymic lesions in piglets infected with attenuated strains of highly pathogenic porcine reproductive and respiratory syndrome virus

    Veterinary Immunology and Immunopathology (2015)

    • The ability of HP-PRRSV inducing thymus atrophy reduced following the virus pathogenicity attenuated; • HP-PRRSV HuN4-F23 strain could still cause the thymus atr...
  4. Effect of common carp (Cyprinus carpio) TLR9 overexpression on the expression of downstream interferon-associated immune factor mRNAs in epithelioma papulosum cyprini cells

    Veterinary Immunology and Immunopathology (2015)

    Toll-like receptors (TLRs) are a class of pattern recognition receptors (PRRs) that recognize pathogen associated molecular patterns (PAMPs) and play an important role in the antiviral response. To determine the effect of common carp TLR9 (CcTLR9) overexpression on the expression of do...
  5. Activation of MEK/ERK pathways through NF-κB activation is involved in interleukin-1β-induced cyclooxygenease-2 expression in canine dermal fibroblasts

    Veterinary Immunology and Immunopathology (2015)

    The proinflammatory cytokine interleukin-1β (IL-1β) induced cyclooxygenases-2 (COX-2) mRNA expression and lipid mediator prostaglandin E2 release and in a time- and dose-dependent manner in canine dermal fibroblasts. The MEK inhibitor U0126 and the ERK inhibitor FR180204 clearly inhibi...
  6. Identification of specific antinuclear antibodies in dogs using a line immunoassay and enzyme-linked immunosorbent assay

    Veterinary Immunology and Immunopathology (2015)

    Circulating antinuclear antibodies (ANA) are commonly present in the systemic autoimmune disease Systemic Lupus Erythematosus (SLE) and in other systemic rheumatic diseases, in humans as well as in dogs. The indirect immunofluorescence (IIF)-ANA test is the standard method for detectin...
  7. Effects of dexamethasone and Mycoplasma bovis on bovine neutrophil function in vitro

    Veterinary Immunology and Immunopathology 164(1-2):67 (2015) PMID 25593042

    It is well established that exposure either to elevated levels of glucocorticoids, or to Mycoplasma bovis (M. bovis), has a negative effect on bovine neutrophil function. The objective of this research was to determine whether in vitro treatment of bovine neutrophils by M. bovis strain...
  8. VapA-specific IgG and IgG subclasses responses after natural infection and experimental challenge of foals with Rhodococcus equi

    Veterinary Immunology and Immunopathology 164(1-2):10 (2015) PMID 25681111

    Rhodococcus equi is a common cause of pneumonia in young foals worldwide and has considerable economic effects on the global equine industry. Despite ongoing efforts, no vaccine is currently available to prevent rhodococaal pneumonia. This is due, in part, to an incomplete understandin...
  9. Immune gene expression in the spleen of chickens experimentally infected with Ascaridia galli

    Veterinary Immunology and Immunopathology 164(1-2):79 (2015)

    • Systemic immune gene expression in the spleen of Ascaridia galli infected chickens was assessed by microfluidic qPCR and found to vary at different time points after experimental infection. ...
  10. Ribavirin stimulates the immune response of Atlantic salmon

    Veterinary Immunology and Immunopathology 164(1-2):93 (2015) PMID 25631788

    • We show that in vitro and in vivo treatments with ribavirin induce cytokines, cell markers and immune molecules expression on kidney and spleen cells. • The expr...