Veterinary Immunology and Immunopathology

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  1. Publisher's Note
    Author(s) unavailable

    Veterinary Immunology and Immunopathology 163(3-4):93 (2015) PMID 25659361

  2. Corrigendum to “Class B CpG ODN stimulation upregulates expression of TLR21 and IFN-γ in chicken Harderian gland cells” [Vet. Immunol. Immunopathol. 160 (2014) 293–299]

    Veterinary Immunology and Immunopathology 161(3-4):271 (2014)

  3. Corrigendum to “Differential responses of macrophages from bovines naturally resistant or susceptible toMycobacterium bovisafter classical and alternative activation” [Vet. Immunol. Immunopathol. 154 (1–2) (2013) 8–16]

    Veterinary Immunology and Immunopathology 160(1-2) (2014)

  4. Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications

    Veterinary Immunology and Immunopathology 159(3-4):192 (2014) PMID 24642290

    The term “lymphoma” describes a heterogeneous group of disorders involving monoclonal proliferation of malignant lymphocytes. As a group, lymphomas are among the most common tumors of dogs. Yet our enumeration and understanding of the many subtypes of lymphoma have been relatively slow...
  5. The role of bovine γδ T cells and their WC1 co-receptor in response to bacterial pathogens and promoting vaccine efficacy: A model for cattle and humans

    Veterinary Immunology and Immunopathology 159(3-4):144 (2014) PMID 24726858

    γδ T cells are critical to immune surveillance and protection since they are found as resident cells in many organs and tissues, including in humans and ruminants, and circulate at substantial numbers in the blood. It is known that γδ T cells contribute to cellular immunity and protect...
  6. Evolutionary characterization of pig interferon-inducible transmembrane gene family and member expression dynamics in tracheobronchial lymph nodes of pigs infected with swine respiratory disease viruses

    Veterinary Immunology and Immunopathology 159(3-4):180 (2014) PMID 24656980

    Studies have found that a cluster of duplicated gene loci encoding the interferon-inducible transmembrane proteins (IFITMs) family have antiviral activity against several viruses, including influenza A virus. The gene family has 5 and 7 members in humans and mice, respectively. Here, w...
  7. The role of gamma delta T cells in immunity to Mycobacterium bovis infection in cattle

    Veterinary Immunology and Immunopathology 159(3-4):133 (2014) PMID 24636303

    Accumulating evidence suggests that γδ T cells play a critical role in the early response to Mycobacterium bovis and may be key in bridging innate and adaptive immunity following infection. In vitro, γδ T cells proliferate and produce robust amounts of IFNγ in response to complex, prot...
  8. Dual purpose use of preterm piglets as a model of pediatric GI disease

    Veterinary Immunology and Immunopathology 159(3-4):156 (2014)

    Necrotizing enterocolitis (NEC) is the most common gastrointestinal complication in human neonates, yet the pathogenesis of this disease remains poorly understood. A fundamental approach to understanding the etiology and underlying biology of NEC is the use of in vivo experimental anim...
  9. Advances in swine immunology help move vaccine technology forward

    Veterinary Immunology and Immunopathology 159(3-4):202 (2014) PMID 24630952 PMCID PMC4107305

    In veterinary animal species, vaccines are the primary tool for disease prevention, a key tool for treatment of infection, and essential for helping maintain animal welfare and productivity. Traditional vaccine development by trial-and-error has achieved many successes. However, effect...
  10. FIV in cats – a useful model of HIV in people?

    Veterinary Immunology and Immunopathology 159(3-4):171 (2014) PMID 24636302

    The feline immunodeficiency virus (FIV) shares genomic organization, receptor usage, lymphocyte tropism, and induction of immunodeficiency and increased susceptibility to cancer with the human immunodeficiency virus (HIV). Global distribution, marked heterogeneity and variable host ada...
  11. Chronic immune stimulation in adipose tissue and its consequences for health and performance in the pig

    Veterinary Immunology and Immunopathology 159(3-4):166 (2014) PMID 24646651

    The pig has been domesticated for about 13,000 years in multiple centers in Europe, Eurasia and China. Chronic inflammation in pigs is a major mitigating factor against optimal health and growth performance. Therefore, strategies for improving health status of pigs must involve downreg...
  12. Dual purpose with dual benefit research models in veterinary and biomedical research

    Veterinary Immunology and Immunopathology 159(3-4):111 (2014) PMID 24629768

  13. Relevance of bovine tuberculosis research to the understanding of human disease: Historical perspectives, approaches, and immunologic mechanisms

    Veterinary Immunology and Immunopathology 159(3-4):113 (2014) PMID 24636301

    Pioneer studies on infectious disease and immunology by Jenner, Pasteur, Koch, Von Behring, Nocard, Roux, and Ehrlich forged a path for the dual-purpose with dual benefit approach, demonstrating a profound relevance of veterinary studies for biomedical applications. Tuberculosis (TB), ...
    Author(s) unavailable

    Veterinary Immunology and Immunopathology 159(3-4):iii (2014)

    Author(s) unavailable

    Veterinary Immunology and Immunopathology 158(1-2):iii (2014)

  16. Analytical validation of a quantitative reverse transcriptase polymerase chain reaction assay for evaluation of T-cell targeted immunosuppressive therapy in the dog

    Veterinary Immunology and Immunopathology 156(3-4):229 (2013)

    Cyclosporine is an immunosuppressive agent that inhibits T-cell function by decreasing production of cytokines such as interleukin-2 (IL-2) and interferon-γ (IFN-γ). In dogs, there is currently no reliable analytical method for determining effective cyclosporine dosages in individual p...
  17. Towards a better understanding of salivary and meat juice acute phase proteins determination in pigs: An expression study

    Veterinary Immunology and Immunopathology 156(1-2):91 (2013) PMID 24144684

    Acute phase proteins (APPs) determination in different fluids like serum, saliva and meat juice measured with ultrasensitive assays can be used to evaluate the disease status of porcine populations under field conditions. Liver is the main production site of serum APPs, but the origin ...
  18. Antibody-dependent enhancement of PRRSV infection down-modulates TNF-α and IFN-β transcription in macrophages

    Veterinary Immunology and Immunopathology 156(1-2):128 (2013) PMID 24099951

    Porcine reproductive and respiratory syndrome (PRRS) is an infectious disease, resulting in important economic losses in pig farming. Previous studies have shown that Fcγ receptor (FcγR)-mediated entry of infectious PRRSV immune complexes into macrophages plays a pivotal role in the pa...
  19. Production of canine soluble CD40 ligand to induce maturation of monocyte derived dendritic cells for cancer immunotherapy

    Veterinary Immunology and Immunopathology 156(1-2):121 (2013) PMID 24144681

    CD40 ligand (CD40L) expressed by activated T cells is shown to induce maturation of immature dendritic cells (DCs) and this maturation is a vital part in DC based tumor immunotherapy. We constructed an expression vector by cloning the extracellular domain of canine CD40L fused to the s...
  20. Inhibition of virus replication and induction of human tetherin gene expression by equine IFN-α1

    Veterinary Immunology and Immunopathology 156(1-2):107 (2013) PMID 24144682

    Type I interferons (IFNs) play important roles in the defense of host cells against viral infection by inducing the expression of a diverse range of antiviral factors. IFNs from different animals likely share similar features with human IFNs, and some of them have cross-species activit...