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Behavioural Brain Research

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  1. Corrigendum to “Accurate performance of a rat model of schizophrenia in the water maze depends on visual cue availability and stability: A d...

    Behavioural Brain Research 282:237 (2015)

  2. Tipepidine increases dopamine level in the nucleus accumbens without methamphetamine-like behavioral sensitization

    Behavioural Brain Research 284:118 (2015)

    • Acute administration of tipepidine increased dopamine levels in the nucleus accumbens. • Tipepidine did not cause behavioral sensitization in rats....
  3. Chronic acarbose treatment alleviates age-related behavioral and biochemical changes in SAMP8 mice

    Behavioural Brain Research 284:138 (2015)

    • Test the sensorimotor ability, anxiety, spatial and non-spatial memory abilities. • Changes of protein level in serum and hippocampus relate to the behavioral defici...
  4. Novel object exploration in the C58/J mouse model of autistic-like behavior.

    Behavioural Brain Research 282:54 (2015) PMID 25532914

    We looked for evidence of higher-order repetitive behaviors in the C58/J strain using a novel object assay. This assay utilized a mouse's natural exploratory behavior among unfamiliar objects to identify potential sequencing patterns in motor activity. The motor stereotypies displayed by the C58/J s...
  5. NR2B antagonist CP-101,606 inhibits NR2B phosphorylation at tyrosine-1472 and its interactions with Fyn in levodopa-induced dyskinesia rat m...

    Behavioural Brain Research 282:46 (2015) PMID 25576965

    We determined abnormal involuntary movements (AIMs) in rats. The levels of NR2B phosphorylation at tyrosine-1472 (pNR2B-Tyr1472) and interactions of NR2B with Fyn in LID rat model were detected by immunoblotting and immunoprecipitation. Results showed that CP-101,606 attenuated l-dopa-induced AIMs....
  6. A comparison of brain volume and cortical thickness in excoriation (skin picking) disorder and trichotillomania (hair pulling disorder) in w...

    Behavioural Brain Research 279:255 (2015) PMID 25435313

    Skin picking disorder (SPD) and trichotillomania (hair pulling disorder, or HPD) significantly overlap in terms of clinical features. However, few studies have directly compared structural brain data in these disorders. The aim of this study was to compare volumes of brain structures and cortical th...
  7. Resurgence of sucrose and cocaine seeking in free-feeding rats.

    Behavioural Brain Research 279:47 (2015) PMID 25446761 PMCID PMC4277906

    Resurgence is relapse of an extinguished operant response following the removal of alternative reinforcement. In animal models of resurgence to date, rats have been food deprived and food is used as the source of alternative reinforcement. Thus, when the alternative reinforcer is removed, the only r...
  8. Omega-3 fatty acids improve behavioral coping to stress in multiparous rats.

    Behavioural Brain Research 279:129 (2015) PMID 25446767

    Behavioral coping refers to the ability to modify behavior to escape from stress, and is protective against the development of depressive disorders. Omega-3 fatty acid (n-3 FA) intake is inversely correlated with anxiety and depression in humans. The objective of this study was to determine if consu...
  9. Amantadine preserves dopamine level and attenuates depression-like behavior induced by traumatic brain injury in rats.

    Behavioural Brain Research 279:274 (2015) PMID 25447294

    We first induced a post-TBI depression rat model to probe the efficacy of amantadine therapy in reducing post-TBI depression. The DA concentration in the striatum of the injured rats, as well as the degeneration and apoptosis of dopaminergic neurons in the substantia nigra (SN), were checked along w...
  10. Neural mechanisms of predatory aggression in rats—Implications for abnormal intraspecific aggression

    Behavioural Brain Research 283:108 (2015)

    We studied the neural background of predatory aggression in rats. • We quantified c-Fos expression in 15 aggression-related brain regions. • The neural substrates of predatory...