Behavioural Brain Research
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Effect of insular cortex inactivation on autonomic and behavioral responses to acute hypoxia in conscious rats.
We studied whether the inactivation of the primary interoceptive posterior insular cortex (pIC) may disrupt the autonomic and behavioral effects of hypoxia in conscious rats. Rats were implanted with telemetric transmitters and microinjection cannulae placed bilaterally in the pIC. After one week, r...
Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway.
We demonstrate that administration of tetramethylpyrazine effectively reverses memory deficits induced by scopolamine. Moreover, tetramethylpyrazine preserves postsynaptic protein synthesis and restores cAMP/PKA/CREB pathway signaling deficits. Our study not only explores the actions of tetramethylp...
Appetitive long-term taste conditioning enhances human visually evoked EEG responses.
Long-term effects of learned associations between an image and a taste have not been studied with electromagnetic brain scanning techniques. The possibility that taste conditioning may change sensory image processing was investigated in young adult subjects. EEG-responses evoked by images were recor...
Inflammatory markers are associated with inhibitory avoidance memory deficit induced by sleep deprivation in rats.
Sleep deprivation (SD) causes detrimental effects to the body, such as memory impairment and weight loss. SD also changes the concentration of inflammatory mediators such as cytokines, which, in turn, can affect cognitive functioning. Thus, the objective of this study was to investigate the involveme...
Functional brain asymmetry in adult novelty response: on fluidity of neonatal novelty exposure effects.
We show that repeated brief exposures to the novelty of a non-home environment during infancy and early adulthood lead to long-lasting changes in adulthood in the global bi-lateralization organization of the brain as indexed by a transiently detectable right-sided orientating bias upon the initial e...
Picture recognition in animals and humans.
Our survey will lead to the conclusion that humans show evidence of picture recognition from an early age; this recognition is, however, facilitated by prior exposure to pictures. This same exposure or training effect appears also to be necessary in nonhuman primates as well as in other mammals and...
Transcutaneous electrical nerve stimulation (TENS) improves the rest-activity rhythm in midstage Alzheimer's disease.
Nightly restlessness in patients with Alzheimer's disease (AD) is probably due to a disorder of circadian rhythms. Transcutaneous electrical nerve stimulation (TENS) was previously reported to increase the strength of coupling of the circadian rest activity rhythm to Zeitgebers in early stage Alzhei...
Effects of medial and lateral caudate-putamen lesions on place- and cue-guided behaviors in the water maze: relation to thigmotaxis.
Rats with dorsomedial or dorsolateral caudate-putamen lesions and sham-operated controls were trained on the standard hidden platform (place) task in the water maze. Compared to controls, rats with dorsomedial, but not dorsolateral lesions were slower to escape to the hidden platform and spent signi...
How skilled are the skilled limb movements of the raccoon (Procyon lotor)?
These results suggest that raccoons are like primates in that they display visual guidance of reaching, but are similar to other carnivores in that they do not use convergent grasping and digit manipulation and frequently use bimanual grasping. The results, consistent with a growing body of informat...
The dorsocaudal neostriatum of the domestic chick: a structure serving higher associative functions.
The dorsocaudal neostriatal (dNC) complex consists of at least three functionally distinct subregions and is part of an 'imprinting' pathway, which interconnects several forebrain regions that are known to be involved in juvenile learning. Based on its anatomical features, at least one subregion of...