Behavioural Brain Research
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Deletion of KCC3 in parvalbumin neurons leads to locomotor deficit in a conditional mouse model of peripheral neuropathy associated with age...
Behavioural Brain Research 274:128 (2014)We established four tissue specific KCC3 knockout mouse lines to explore the cell population origin of ACCPN. Our results showed that the loss of KCC3 in parvalbumin-positive neurons led to significant locomotor deficit, suggesting a crucial role of these neurons in the development of the locomotor...
Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice
Behavioural Brain Research 274:118 (2014)• Ethological phenotypes in HD mice may be altered by stress hormone treatment. • CORT impaired olfactory function and hedonic response in female WT and HD mice....
Chronic social stress does not affect behavioural habituation in male CD1 mice
Behavioural Brain Research 273:34 (2014)• CD1 male adolescent mice were exposed to chronic social stress (CSS). • A decreased body weight gain, fur condition and GR mRNA indicated effectiveness of the protoc...
Effect of insular cortex inactivation on autonomic and behavioral responses to acute hypoxia in conscious rats.
We studied whether the inactivation of the primary interoceptive posterior insular cortex (pIC) may disrupt the autonomic and behavioral effects of hypoxia in conscious rats. Rats were implanted with telemetric transmitters and microinjection cannulae placed bilaterally in the pIC. After one week, r...
Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway.
We demonstrate that administration of tetramethylpyrazine effectively reverses memory deficits induced by scopolamine. Moreover, tetramethylpyrazine preserves postsynaptic protein synthesis and restores cAMP/PKA/CREB pathway signaling deficits. Our study not only explores the actions of tetramethylp...
Appetitive long-term taste conditioning enhances human visually evoked EEG responses.
Long-term effects of learned associations between an image and a taste have not been studied with electromagnetic brain scanning techniques. The possibility that taste conditioning may change sensory image processing was investigated in young adult subjects. EEG-responses evoked by images were recor...
Inflammatory markers are associated with inhibitory avoidance memory deficit induced by sleep deprivation in rats.
Sleep deprivation (SD) causes detrimental effects to the body, such as memory impairment and weight loss. SD also changes the concentration of inflammatory mediators such as cytokines, which, in turn, can affect cognitive functioning. Thus, the objective of this study was to investigate the involveme...
Functional brain asymmetry in adult novelty response: on fluidity of neonatal novelty exposure effects.
We show that repeated brief exposures to the novelty of a non-home environment during infancy and early adulthood lead to long-lasting changes in adulthood in the global bi-lateralization organization of the brain as indexed by a transiently detectable right-sided orientating bias upon the initial e...
Picture recognition in animals and humans.
Our survey will lead to the conclusion that humans show evidence of picture recognition from an early age; this recognition is, however, facilitated by prior exposure to pictures. This same exposure or training effect appears also to be necessary in nonhuman primates as well as in other mammals and...
Transcutaneous electrical nerve stimulation (TENS) improves the rest-activity rhythm in midstage Alzheimer's disease.
Nightly restlessness in patients with Alzheimer's disease (AD) is probably due to a disorder of circadian rhythms. Transcutaneous electrical nerve stimulation (TENS) was previously reported to increase the strength of coupling of the circadian rest activity rhythm to Zeitgebers in early stage Alzhei...