Trends in Biotechnology
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Emerging microengineered tools for functional analysis and phenotyping of blood cells
Light emitting diodes (LEDs) applied to microalgal production.
Light-emitting diodes (LEDs) will become one of the world's most important light sources and their integration in microalgal production systems (photobioreactors) needs to be considered. LEDs can improve the quality and quantity of microalgal biomass when applied during specific growth phases. Howev...
Non-invasive wearable electrochemical sensors: a review.
Wearable sensors have garnered considerable recent interest owing to their tremendous promise for a plethora of applications. Yet the absence of reliable non-invasive chemical sensors has greatly hindered progress in the area of on-body sensing. Electrochemical sensors offer considerable promise as...
What place for polyacrylamide in proteomics?
Trends in Biotechnology 19:3 (2001)We describe the progress made towards establishing 2D-PAGE as the optimal separation tool for proteomics research....
Novel vaccine technologies.
Towards XNA nanotechnology: new materials from synthetic genetic polymers.
Nucleic acids display remarkable properties beyond information storage and propagation. The well-understood base pairing rules have enabled nucleic acids to be assembled into nanostructures of ever increasing complexity. Although nanostructures can be constructed using other building blocks, includi...
Lab-on-a-chip technologies for stem cell analysis.
We address recent lab-on-a-chip developments for stem cell analysis. We highlight in particular the tangible advantages of microfluidic devices to overcome most of the challenges associated with stem cell identification, expansion and differentiation, with the greatest advantage being that lab-on-a-...
From fingerprinting to kinetics in evaluating food quality changes.
Historically, the study of food quality changes during processing, preservation, and storage has evolved from targeted, single-response studies towards studies relying on both targeted and untargeted approaches analyzing multiple responses. In our opinion, future studies should be based on a zoom-in...
Point-of-care technologies for molecular diagnostics using a drop of blood.
Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and...
Diatoms: a fossil fuel of the future.
We focus on a specific algal taxon, diatoms, to become the fossil fuel of the future. We summarize past attempts to obtain suitable diatom strains, propose future directions for their genetic manipulation, and offer biotechnological pathways to improve yield. We calculate that the yields obtained by...