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Developing and applying of a parentage identification approach based on high density genetic markers.
Pedigree is an important information source in the studies on human genetics and animal/plant breeding. Pedigree error is a common data error in breeding practice. It can affect the reliability of results from researches such as gene mapping, genetic or phenotypic value prediction. By using genetic...
[The discussion of the infiltrative model of mathematical knowledge to genetics teaching].
We applied some mathematical infiltrative model genetic knowledge in genetics teaching, which could help students more deeply learn and understand genetic knowledge....
[Advances of transgenic breeding in livestock].
Transgenic technology represents a revolutionary way to produce elite livestock breeds, allowing introduction of alien gene into livestock genome. Currently, pronuclear microinjection of DNA and somatic cell nuclear transfer are two popular methods used to make transgenic farm animals. Transgenic tec...
[Association of mismatch repair gene polymorphism with susceptibility to sporadic colorectal cancer in Tianjin region].
These results indicate that hMSH2 2783C/A polymorphism has potential to be a susceptibility factor for SCRC and the 394G/943-1G /2783A haplotype might increase the risk of developing SCRC....
[Research progress in modification of histone lysine methylation and congenital heart defect].
We discussed the mechanism of histone lysine methylation related to congenital heart defect in order to provide a useful reference for researchers working in this area....
[Polymorphism of MHC-DPB1 gene exon 2 in rhesus macaques (Macaca mulatta)].
Rhesus macaque (Macaca mulatta) has long been used as an experimental model animal for biomedical research and was under the key state protection (class II) from Chinese government. In order to facilitate the use of Chinese rhesus macaques in biomedical research and their protection based on better...
[miR-34s--a tumor suppression protein p53 highly related microRNA].
I (SIRTI). The positive feedback regulatory network based on p53 and miR-34 families play an important role in suppression of oncogenesis and deterioration. This paper summarizes the latest advances of p53 highly related miR-34 families in oncogenesis and treatment....
[Male infertility and gene defects].
About 15% of the couples at reproductive age worldwide suffer from infertility. It is estimated that 50% of the entity result from male itself. The mechanism of male infertility is quite complicated, attributing to inherent and environment factors of the infertility patients, of which defects of fer...
[Jack william szostak.]
[Anassociation study between OPHN1 gene rs492933 polymorphism and mental retardation in children of the Qinba Mountain region.].
The OPHN1 gene encodes a Rho-GTPase activating protein (RhoGAP), and mutations in OPHN1 are responsible for non-specific X-linked mental retardation (NSMR). A SNP located in the 5'-untranslated region (UTRs) of OPHN1 (rs492933) was examined by PCR-RFLP to assess its contribution to cognitive ability...