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Hereditas (Beijing)

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  1. [In Process Citation].
    Author(s) unavailable

    Hereditas (Beijing) 37(5):409 (2015) PMID 25998427

  2. [In Process Citation].
    Author(s) unavailable

    Hereditas (Beijing) 37(5):499 (2015) PMID 25998440

  3. The function of PlcR in Bacillus anthracis vaccine strain A16R.

    Hereditas (Beijing) 37(5):494 (2015) PMID 25998439

    Bacillus anthracis, B. thuringiensis and B. cereus are members of the B. cereus group. They share high genetic similarity. Whereas plcR (Phospholipase C regulator) usually encodes a functional pleiotropic activator protein in B. cereus and B. thuringiensis isolates, a characteristic nonsense mut...
  4. Distinct quasispecies characteristics and positive selection within the core gene in chronic hepatitis B virus infected child and adult patients.

    Hereditas (Beijing) 37(5):465 (2015) PMID 25998435

    There are significant differences in clinical characteristics between chronic hepatitis B virus infected (CHB) child and adult patients. Viral quasispecies characteristics are associated with its pathogenic properties. For hepatitis B virus (HBV), its core region is the main immune recognition r...
  5. Genetic characteristics of vancomycin resistance gene cluster in Enterococcus spp.

    Hereditas (Beijing) 37(5):452 (2015) PMID 25998433

    Vancomycin resistant enterococci has become an important nosocomial pathogen since it is discovered in late 1980s. The products, encoded by vancomycin resistant gene cluster in enterococci, catalyze the synthesis of peptidoglycan precursors with low affinity with glycopeptide antibiotics includi...
  6. Adaptation strategies: how environmental fungi become fatal?

    Hereditas (Beijing) 37(5):436 (2015) PMID 25998431

    Most fungi contributing to systemic human infections are environmental pathogens, whose fatal pathogenicity is largely derived from their survival strategies developed to adapt to a plethora of natural stressors. A well-studied example of such pathogens is Cryptococcus neoformans. C. neoformans ...
  7. Application of the SCCmec element in the molecular typing of methicillin-resistant Staphylococcus aureus.

    Hereditas (Beijing) 37(5):442 (2015) PMID 25998432

    Acquisition of the staphylococcal chromosome cassette mec (SCCmec) is one of the key reasons for the resistance of methicillin-resistant Staphylococcus aureus (MRSA). SCCmec is composed of a mec gene complex encoding the PBP2a determinant that is responsible for the β-lactam resistance of MRSA, ...
  8. The effect of quorum sensing system for growth competitiveness on Shigella flexneri.

    Hereditas (Beijing) 37(5):487 (2015) PMID 25998438

    Quorum sensing (QS) regulates the onset of bacterial social responses related to cell density. Comparison between the gene sequences of all components of QS system of Escherichia coli and Shigella strains, shows that the QS system is generally lost or mutated in Shigella. Since AI-2 is produced ...
  9. Update on antimicrobial resistance in Clostridium difficile.

    Hereditas (Beijing) 37(5):458 (2015) PMID 25998434

    Clostridium difficile is the leading cause of healthcare-associated diarrhea. Since 2002, the morbidity and mortality rates of C. difficile infection have increased dramatically in Europe and North America. The emergence of C. difficile strains that are resistant to multiple antimicrobial agents...
  10. [The application of CRISPR-Cas9 gene editing technology in viral infection diseases].

    Hereditas (Beijing) 37(5):412 (2015) PMID 25998428

    The RNA-guided Cas9 nuclease from microbial clustered regularly interspaced short palindromic repeats (CRISPR) adaptive immune system has been used to facilitate efficient genome engineering in eukaryotic cells. The specific targeted genome is recognized and cut by gRNA-directed CRISPR/Cas9 comp...