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- Ovid from 2005, CSA, Wiley from 1984, Proquest, and Gale
Did the fire ant supergene evolve selfishly or socially?
The genetic basis for animal social organization is poorly understood. Fire ants provide one of the rare cases where variation in social organization has been demonstrated to be under genetic control, which amazingly, segregates as a single Mendelian locus. A recent genetic, genomic, and cytological...
Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks.
We first discuss the general characteristics of insulator elements and their associated protein factors. A growing collection of insulator proteins have been identified including a family of proteins whose expression is developmentally regulated. We next consider several unexpected discoveries that...
3'UTRs take a long shot in the brain.
We review recent progress in the characterization of mRNA 3'UTRs and discuss their implications in the understanding of 3'UTR-mediated gene regulation. © 2014 WILEY Periodicals, Inc....
Horizontal gene acquisitions by eukaryotes as drivers of adaptive evolution.
We raise the hypothesis that horizontally acquired genes may have contributed more to adaptive evolution of eukaryotes than previously assumed. Current candidate sets of horizontally acquired eukaryotic genes may just be the tip of an iceberg. We have recently shown that adaptation of the thermoacid...
Retroviruses facilitate the rapid evolution of the mammalian placenta.
I propose that ERV-mediated regulatory evolution was, and continues to be, an important mechanism underlying the evolution of placental development. Many recent studies have focused on the co-option of ERV-derived genes for specific functional adaptations in the placenta. However, the co-option of E...
Phenotypes from ancient DNA: approaches, insights and prospects.
The great majority of phenotypic characteristics are complex traits, complicating the identification of the genes underlying their expression. However, both methodological and theoretical progress in genome-wide association studies have resulted in a much better understanding of the underlying genet...
BiotecVisions 2013, June (pages A1-A8).
Back to the beginning: The initiation of cancer.
The promise and challenges of stem cell-based therapies for skeletal diseases: Stem cell applications in skeletal medicine: Potential, cell ...
Despite decades of research, remaining safety concerns regarding disease transmission, heterotopic tissue formation, and tumorigenicity have kept stem cell-based therapies largely outside the standard-of-care for musculoskeletal medicine. Recent insights into trophic and immune regulatory activities...
Mitochondria, maternal inheritance, and asymmetric fitness: Why males die younger.
We discuss this new work and identify some areas of future research that might now be encouraged to explore what may be the underpinning cause of the strong sexual dimorphism in aging. Editor's suggested further reading in BioEssays: Mitonuclear match: Optimizing fitness and fertility over generatio...