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  1. Editorial Board
    Author(s) unavailable

    Biochimie 112:IFC (2015)

  2. MR (Mre11-Rad50) complex in Giardia duodenalis: In vitro characterization and its response upon DNA damage

    Biochimie 111:45 (2015) PMID 25662961

    Giardia duodenalis is a well-known protozoan parasite of humans and other mammals. The repair of DNA double strand breaks (DSBs) is crucial for genomic stability and homologous recombination is one of the primary mechanisms used by cells to repair DNA. The Mre11 complex is comprised by...
  3. Camelid single-domain antibody fragments: Uses and prospects to investigate protein misfolding and aggregation, and to treat diseases associated with these phenomena

    Biochimie 111:82 (2015)

    The deposition of misfolded peptides and proteins in the form of amyloid fibrils is the hallmark of nearly fifty medical disorders, including Alzheimer's disease, Parkinson's disease, prion diseases and type II diabetes. These disorders, referred to as amyloidoses, generally become app...
  4. Crystal structure analysis of peroxidase from the palm tree Chamaerops excelsa

    Biochimie 111:58 (2015) PMID 25660651

    Palm tree peroxidases are known to be very stable enzymes and the peroxidase from the Chamaerops excelsa (CEP), which has a high pH and thermal stability, is no exception. To date, the structural and molecular events underscoring such biochemical behavior have not been explored in dept...
  5. ATDOF5.8 protein is the upstream regulator of ANAC069 and is responsive to abiotic stress

    Biochimie 110:17 (2015) PMID 25572919

    ANAC069 encodes a plasma membrane-bound NAC protein that integrates auxin and salt signals to regulate Arabidopsis thaliana seed germination. However, the regulatory network of ANAC069 has not been revealed. Here, we report that ANAC069 is a direct target gene of the ATDOF5.8 transcrip...
  6. Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs

    Biochimie 110:36 (2015) PMID 25576830

    Estrogen plays an essential role in bone formation, and estrogen modulation dysfunction is tightly associated with postmenopausal osteoporosis (PMOP). The underlying mechanisms of estrogen-mediated osteogenic differentiation have not been well defined. In this study, murine bone marrow...
  7. Insight into the structural flexibility and function of Mycobacterium tuberculosis isocitrate lyase

    Biochimie 110:73 (2015) PMID 25576828

    Isocitrate lyase (ICL), is a key enzyme of the glyoxylate shunt crucial for the survival of Mycobacterium tuberculosis (Mtb) in macrophages during persistent infection. MtbICL catalyses the first step of this carbon anaplerosis cycle and is considered as a potential anti-tubercular dru...
  8. Editorial board
    Author(s) unavailable

    Biochimie 110:IFC (2015)

  9. Mechanistic insights into the inhibitory effects of palmitoylation on cytosolic thioredoxin reductase and thioredoxin

    Biochimie 110:25 (2015) PMID 25576832

    Overnutrition can lead to oxidative stress, but its underlying mechanism remains unclear. In this study, we report that human liver-derived HepG2 cells utilize cytosolic thioredoxin reductase (TrxR1) and thioredoxin (hTrx1) to defend against the high glucose/palmitate-mediated increase...
  10. Eicosapentaenoic acid modulates fatty acid metabolism and inflammation in Psammomys obesus

    Biochimie 109:60 (2015) PMID 25528298

    The desert gerbil, Psammomys obesus, is a unique polygenic animal model of metabolic syndrome (insulin resistance, obesity and type 2 diabetes), and these pathological conditions resemble to those in human beings. In this study, the animals were fed ad libitum either a natural diet (ND...