Progress in Neurobiology
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- Rcgp, Proquest, Ingenta, Gale, CSA, and Sciencedirect from 1973
The neurotoxicity of mutant proteins 20 years after the discovery of the first mutant gene involved in neurodegeneration. Foreword.
The future of Alzheimer's disease: the next 10 years.
Alzheimer's disease (AD) is a fast growing world-wide epidemic. AD is a genetically complex, slowly progressive, and irreversible neurodegenerative disease of the brain. During decades of asymptomatic progression multiple interactive systems, pathways and molecular mechanisms (e.g. p...
Cdk5: Multitasking between physiological and pathological conditions
Cyclin-dependent kinase 5 (Cdk5) is a peculiar proline-directed serine/threonine kinase. Unlike the other members of the Cdk family, Cdk5 is not directly involved in cell cycle regulation, being normally associated to neuronal processes such as migration, cortical layering and synapt...
Effects of incremental exercise on cerebral oxygenation measured by near-infrared spectroscopy: A systematic review
We conducted a systematic review and meta-regression analysis to quantify effects of exercise on brain hemodynamics measured by near-infrared spectroscopy (NIRS). The results indicate that acute incremental exercise (categorized relative to aerobic capacity (VO(2)peak) as low - <30% VO(2)peak; moder...
Deep brain stimulation in neurological diseases and experimental models: From molecule to complex behavior
We review the clinical data and experimental work in vitro, ex vivo and in vivo (mostly arisen from studies on DBS of the subthalamic nucleus) in the treatment of PD, which led to the actual knowledge of DBS mechanisms, from molecular to complex behavioral levels....
Neuroplasticity in amputees: Main implications on bidirectional interfacing of cybernetic hand prostheses
We hereby critically review the literature concerning neuroplastic phenomena in amputees, in terms of changes at different CNS levels, particularly for their implications on the development of bidirectional neural interfaces for cybernetic hand prostheses. Our analysis of the literature demonstrates...
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