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  1. Evolvability.

    Biosystems 69(2-3):77 (2003) PMID 12689722

  2. Modelling effects of high product and substrate inhibition on oscillatory behavior in continuous bioreactors.

    Biosystems 49(3):191 (1999) PMID 10193759

    We consider a model for continuous bioreactors which incorporates the effects of high product and substrate inhibition on the kinetics as well as biomass and product yields. We theoretically investigate the possibility of various dynamic behaviors in the bioreactor over different ranges of operating...
  3. Using genetic algorithms for the construction of phylogenetic trees: application to G-protein coupled receptor sequences.

    Biosystems 49(1):31 (1999) PMID 10091971

    Many different phylogenetic clustering techniques are used currently. One approach is to first determine the topology with a common clustering method and then calculate the branch lengths of the tree. If the resulting tree is not optimal exchanging tree branches can make some local c...
  4. Consciousness as a self-organizing process: an ecological perspective.

    Biosystems 46(1-2):123 (1998) PMID 9648683

    The evolution of consciousness is seen in the context of energy-driven evolution in general, where energy and information are understood as two sides of the same coin. From this perspective consciousness is viewed as an ecological system in which streams of cognitive, perceptual, and emotional infor...
  5. Social information: the person is the message.

    Biosystems 46(1-2):137 (1998) PMID 9648685

    Assumptions that Shannon's concepts cannot extend to social systems are challenged by showing that social information measures the reduced uncertainties individuals have about the systemic effects of each other's behavior. The 'meaning' of individual actions is their collective consequences, which a...
  6. Gamma oscillations by synaptic inhibition in a homogeneous medium model of hippocampal interneurons.

    Biosystems 48(1-3):165 (1998) PMID 9886644

    Population of interacting inhibitory hippocampal neurons is described by a continuous model. The explicit equation for the frequency of synchronized neural firing and the condition for its stability are obtained. The results of their numerical solution are in quantitative agreement with the data of...
  7. The genetic code as a Golden mean determined system.

    Biosystems 46(3):283 (1998) PMID 9668964

    For the first time it is shown that the genetic code, as a binary code, is determined by Golden mean through the unity of the binary-code tree and the Farey tree, corresponding to the Watson-Crick table and Gray code model of the genetic code at the same time. On the other hand, the Golden mean rela...
  8. A quantum-theoretical approach to the phenomenon of directed mutations in bacteria (hypothesis).

    Biosystems 43(2):83 (1997) PMID 9231907

    I propose that the explanation of this phenomenon should not rely on any special 'mechanism' for the appearance of directed mutations, but rather should be based on the principles of quantum theory. I consider a physical model of adaptation whereby a polarized photon, passing through a polarizer, ch...
  9. Some remarks on the experimental realization of a mind machine.

    Biosystems 42(2-3):207 (1997) PMID 9184765

    The brain not only makes use of measuring apparatuses, but perhaps has the potential to serve as one itself. Since Einstein-Podolsky-Rosen correlations must be absent between observer and object in order for a quantum state to become reducible, it is tempting to perturb measurements by changing the...
  10. Computational properties of self-reproducing growing automata.

    Biosystems 36(1):7 (1995) PMID 8527697

    Living organisms perform much better than computers at solving complex, irregular computational tasks, like search and adaptation. Key features of living organisms, identified in the paper as a basis for their success in solving complex problems, are: self-reproduction of cells, flexible framework,...