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Commentary on: Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.
Early sexual experience alters voluntary alcohol intake in adulthood
Neuroscience Letters 563:129 (2014)• Sexual experience during adolescence but not adulthood increases alcohol self-administration. • Sexual experience increased anxiety- and depressive-like behaviors....
Comparative analysis of vestibular receptor and baroreceptor inputs to the nucleus tractus solitarius following acute hypotension in conscio...
Neuroscience Letters 563:70 (2014)• c-Fos protein following acute hypotension was measured in NTS of conscious rats. • Activation in NTS following acute hypotension is largely due to baroreceptor input...
Acetylsalicylic acid enhances tachyphylaxis of repetitive capsaicin responses in TRPV1-GFP expressing HEK293 cells
Neuroscience Letters 563:101 (2014)Our data suggest inhibition of the cloned TRPV1 by low ASA doses independent of COX....
Association between PITX3 promoter polymorphism and risk of Parkinson's disease: The impact of ethnicity and onset age.
The association between the functional SNP (rs3758549) in the promoter region of PITX3 gene and risk of Parkinson's disease (PD) remains controversial. The present study aimed at investigating the pooled association using a meta-analysis on the published studies. A total of nine studies (comprising...
Simultaneous activation of mitophagy and autophagy by staurosporine protects against dopaminergic neuronal cell death.
We report that staurosporine activates both autophagy and mitophagy simultaneously during dopaminergic neuronal cell death, and evaluate the physiological significance of these processes during cell death. First, staurosporine treatment resulted in induction of autophagy in more than 75% of apoptoti...
The interaction between tropomyosin-related kinase B receptors and serine kinases modulates acetylcholine release in adult neuromuscular jun...
We conducted an electrophysiological study of the functional link between the tropomyosin-related kinase B (trkB) receptor signaling mechanism and serine-threonine kinases, both protein kinase C (PKC) and protein kinase A (PKA). We describe their coordinated role in transmitter release at the neurom...
About the cortical origin of the low-delta and high-gamma rhythms observed in EEG signals during treadmill walking.
Our results indicate that up to 15 harmonics of the fundamental stepping frequency may pollute EEG signals, depending on the walking speed and also on the electrode location. This finding may call into question some conclusions drawn in previous EEG studies where low-delta band (especially around 1H...
β1-adrenoceptor stimulation enhances the differentiation of mouse induced pluripotent stem cells into neural progenitor cells.
We examined the involvement of β-adrenoceptor signaling on the differentiation of mouse induced pluripotent stem (iPS) cells into neural progenitor cells. Mouse iPS cells were cultured on ultra-low-attachment dishes to induce embryoid body (EB) formation. All-trans retinoic acid (ATRA, 1μM) and/or...
Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice.
Animal models are an integral part of pain research. However, current models tend to rely on evoked responses and there is a belief that non-evoked responses may be a more relevant behavioural readout as the animal responds in a more natural manner. Here, dynamic weight bearing (DWB)...