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- Ovid from 2001, Aacr, Nephrology, Rupress, Aaas, CSA, Endocrine, Csh, Ama, Proquest, Highwire from 1981, Ingenta, Rcgp, Gale, Sage, and Highwire
Lack of hemodynamic interaction between CGRP-receptor antagonist telcagepant (MK-0974) and sumatriptan: Results from a randomized study in p...
The objective of this article is to assess the effects of sumatriptan monotherapy, telcagepant monotherapy, and their combination on blood pressure (BP) in migraine patients during a headache-free period. A double-blind, placebo-controlled, four-period, single-dose, randomized crossover study in 24...
Occipital nerve stimulation in medically intractable, chronic cluster headache. The ICON study: rationale and protocol of a randomised trial...
We have introduced a new design in pain neuromodulation by which we think we can overcome this problem. We propose a prospective, randomised, double-blind, parallel-group international clinical study in medically intractable, chronic cluster headache patients of high- versus low-amplitude ONS. Prima...
A new animal model of headache: Ongoing pain vs stimulus-evoked hypersensitivity.
The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels.
We explored the effects of the FHM-1 K1336E mutation on G protein-dependent modulation of the recombinant P/Q-type channel. The mutation was introduced into the human CaV2.1α1 subunit and its functional consequences investigated after heterologous expression in HEK-293 cells using patch-clamp record...
Psychiatric comorbidity in pediatric chronic daily headache.
The objectives of this study were to assess comorbid psychiatric diagnoses in youth with chronic daily headache (CDH) and to examine relationships between psychiatric status and CDH symptom severity, as well as headache-related disability. Standardized psychiatric interviews (Kiddie Schedule for Aff...
Results of a 2-year retrospective cohort study of newly prescribed triptan users in European nationwide practice databases.
We conducted a retrospective cohort analysis to identify refill patterns over 2 years among migraineurs receiving new prescriptions of triptan monotherapy in 2006. Of all patients, >33% of migraineurs with new triptan prescriptions received ≥1 refill of their index triptan prescriptions (UK, 44.3%;...
How general practitioners treat migraine patients: evaluation of a headache guideline.
The aim of the study was to evaluate the pharmacological treatment of migraine patients by general practitioners before referral to a neurologist. First, was the pharmacological treatment in accordance with the Dutch College of General Practitioners headache guideline? Second, which migraine charact...
Board walk - july 2012.
Increased RLS prevalence in children and adolescents with migraine: a case-control study.
The frequency of RLS in migraine patients was significantly higher than in controls (22% vs. 5% (p < 0.001)).Discussion: This is the first study suggesting an association between RLS and migraine in the pediatric population. Future studies are needed to determine the exten...
Posterior circulation embolism as a potential mechanism for migraine with aura.
We describe a 19-year-old female with recurrent migraine attacks and typical aura for 7 years. MRI showed multiple stroke lesions in the posterior circulation. Moreover, a pseudoaneurysm (1.9 × 1.4 cm) originating from the left vertebral artery was observed on four-vessel angiography. Multi...