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Opportunities for prevention of alcohol-related death in primary care: results from a population-based cross-sectional study.
We carried out a cross-sectional study on patients who died from alcohol-related conditions in the calendar year 2003 within National Health Service Greater Glasgow Health Board area, Scotland (population 920,000). We described patient characteristics and care recorded in health service records, com...
Anti-hepatitis B core positivity as a risk factor for hepatocellular carcinoma in alcoholic cirrhosis: a case-control study.
We investigated whether anti-hepatitis B core (HBc) positivity or occult hepatitis B virus (HBV) infection is a risk factor for HCC in patients with alcoholic cirrhosis. Between January 2006 and August 2008, a total of 72 cirrhotic male patients with an initial diagnosis of HCC, hospitalized in thre...
Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence.
This review represents the focus of a symposium that was presented at the "Alcoholism and Stress: A Framework for Future Treatment Strategies" conference in Volterra, Italy on May 3-6, 2011 and organized/chaired by Dr. Brendan M. Walker. The primary goal of the symposium was to evaluate and dissemin...
Serum and plasma brain-derived neurotrophic factor (BDNF) in abstinent alcoholics and social drinkers.
We observed between plasma and serum levels are congruent with their representing separate pools of BDNF. The observation of higher basal serum BDNF in the AD group without a concomitant elevation in plasma BDNF levels indicates that the elevated serum BDNF in AD patients is not due to greater BDNF...
Estimation of blood alcohol concentration by horizontal attenuated total reflectance-Fourier transform infrared spectroscopy
Numerous methods like distillation followed by iodometric titrations, gas chromatograph (GC)-flame ionization detector, gas chromatograph-mass spectrophotometer, GC-Headspace, Breath analyzer, and biosensors including alcohol dehydrogenase (enzymatic) have been used to determine blood alcohol concen...
Roles of neural stem cells and adult neurogenesis in adolescent alcohol use disorders.
This review discusses the contributions of a newly considered form of plasticity, the ongoing production of new neurons from neural stem cells, or adult neurogenesis, within the context of neuropathologies that occur with excessive alcohol intake in the adolescents. Neural stem cells and adult neuro...
Acute alcohol treatment attenuates LPS-induced macrophage TNF@a production through Bcl3 induction and Bcl3-NF-@kB p50 interaction
The role of the small GTPase Rac in macrophage phagocytosis after acute ethanol exposure
Activation of PI3K/Akt pathway in neutrophil following alcohol and burn injury
Intermittent access to beer promotes binge-like drinking in adolescent but not adult Wistar rats