Diabetic Medicine

Print ISSN
Electronic ISSN
Impact factor
Usage rank
Article count
Free count
Free percentage
PDFs via platforms
Rcgp, Gale, CSA, Wiley, Ingenta, Ovid from 2001, and Proquest

  1. Oestradiol replacement treatment and glucose homeostasis in two men with congenital aromatase deficiency: evidence for a role of oestradiol and sex steroids imbalance on insulin sensitivity in men.

    Diabetic Medicine 24(12):1491 (2007) PMID 17976198

    The role of sex steroids in glucose and insulin metabolism in men remains unclear. To investigate the effects of sex steroids and oestrogen on insulin sensitivity in men, we studied two male adults with aromatase deficiency (subject 1 and subject 2). The effects of transdermal oestradiol (tE(2))...
  2. An angled insertion technique using 6-mm needles markedly reduces the risk of intramuscular injections in children and adolescents.

    Diabetic Medicine 24(12):1400 (2007) PMID 18042081

    The aims of this study were (i) to establish which children with Type 1 diabetes are at risk of intramuscular or intradermal insulin injections and (ii) to determine a needle length and technique that reliably administers insulin into subcutaneous fat. Seventy-two healthy diabetic children (age ...
  3. Lipoatrophy is a thing of the past, or is it?

    Diabetic Medicine 24(12):1470 (2007) PMID 17976201

    We describe the development of severe lipoatrophy in a patient treated with biphasic aspart. This complication of insulin therapy was common in the past with the use of animal insulins and became less common with the increasing purification of these and the introduction of recombinant human insu...
  4. Pregnancy-associated plasma protein A in a large cohort of Type 1 diabetic patients with and without diabetic nephropathy-a prospective follow--up study.

    Diabetic Medicine 24(12):1381 (2007) PMID 17971180

    Pregnancy-associated plasma protein A (PAPP-A) has been implicated in the aetiology of acute coronary syndromes and carotid and peripheral artherosclerosis. Diabetic nephropathy is characterized by increased cardiovascular risk. We investigated the prognostic value of PAPP-A in a large cohort of...
  5. Serum angiotensin-converting enzyme and frequency of severe hypoglycaemia in Type 1 diabetes: does a relationship exist?

    Diabetic Medicine 24(12):1449 (2007) PMID 17894828

    An association has been described between elevated serum angiotensin-converting enzyme (ACE) and an increased risk of severe hypoglycaemia (SH). To ascertain whether this reported association could be replicated in a different country, it was re-examined in 300 individuals with Type 1 diabetes. ...
  6. Diagnostic potential of serum protein pattern in Type 2 diabetic nephropathy.

    Diabetic Medicine 24(12):1386 (2007) PMID 18042080

    Microalbuminuria is the earliest clinical sign of diabetic nephropathy (DN). However, the multifactorial nature of DN supports the application of combined markers as a diagnostic tool. Thus, another screening approach, such as protein profiling, is required for accurate diagnosis. Surface enhanc...
  7. Low-risk HLA genotype in Type 1 diabetes is associated with less destruction of pancreatic B-cells 12 months after diagnosis.

    Diabetic Medicine 24(12):1487 (2007) PMID 17971177

    The role of human leukocyte antigen (HLA) genes in the susceptibility to Type 1 diabetes (T1DM) is well known. However, we do not know whether the degree of pancreatic B-cell destruction depends on different HLA genetic risk. The aim of this study was to analyse the influence of DRB1* and DQB1* ...
  8. Inverse correlation between activated protein C generation and carotid atherosclerosis in Type 2 diabetic patients.

    Diabetic Medicine 24(12):1322 (2007) PMID 17971179

    Activated protein C (APC) is a key regulator of the clotting system and immune responses. We studied the relationship between the degree of atherosclerosis as measured by the intima-media thickness (IMT) of carotid artery and APC generation in Type 2 diabetic patients. Eighty-seven Type 2 diabet...
  9. Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes.

    Diabetic Medicine 24(12):1345 (2007) PMID 17971181

    To determine in Type 1 diabetes patients if levels of pigment epithelium-derived factor (PEDF), an anti-angiogenic, anti-inflammatory and antioxidant factor, are increased in individuals with complications and positively related to vascular and renal dysfunction, body mass index, glycated haemog...
  10. Significant bacteriuria in outpatient diabetic and non-diabetic persons.

    Diabetic Medicine 24(12):1455 (2007) PMID 17941860

    The prevalence of significant bacteriuria (SB) in diabetes mellitus has not been clearly established. Having previously investigated SB frequency in inpatient diabetic women, we now screened for SB (both asymptomatic and symptomatic forms) in outpatients. We examined 511 consecutive outpatients ...
  11. Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes.

    Diabetic Medicine 24(12):1329 (2007) PMID 17941863

    Interaction of vascular and metabolic factors appears to contribute to the pathogenesis of diabetic neuropathy. The aim of the study was to assess the impact of arterial stiffening and thickness on diabetic neuropathy in Type 2 diabetes. In 294 patients with Type 2 diabetes, neuropathy was asses...
  12. Serum uric acid, mortality and glucose control in patients with Type 2 diabetes mellitus: a PreCIS database study.

    Diabetic Medicine 24(12):1369 (2007) PMID 17976199

    To determine the association of serum uric acid with all-cause mortality and hyperglycaemia in patients with Type 2 diabetes. Retrospective cohort analysis of 535 consecutive patients who had uric acid determinations between 1998 and 2004 and whose subsequent vital status was determined at a med...
  13. Recommendations for designing tables that report randomized trials.

    Diabetic Medicine 24(12):1309 (2007) PMID 17976200

  14. Performance and comparison of the Cockcroft-Gault and simplified Modification of Diet in Renal Disease formulae in estimating glomerular filtration rate in a Chinese Type 2 diabetic population.

    Diabetic Medicine 24(12):1482 (2007) PMID 17971183

    Our aim was to assess performances of the Cockcroft-Gault and simplified Modification of Diet in Renal Disease (MDRD) formulae in estimating glomerular filtration rate (GFR) in Chinese diabetic populations and their association with vascular risks. A total of 1009 patients with Type 2 diabetes w...
  15. Quality of diabetes care in patients with schizophrenia and bipolar disorder: cross-sectional study.

    Diabetic Medicine 24(12):1442 (2007) PMID 18042084

    To determine whether patients with severe mental illness receive poorer health care for diabetes than patients without. This population-based cross-sectional survey used electronic general practice records from 481 UK general practices contributing to the QRESEARCH database. The records of 11 04...
  16. Use of metformin according to estimated glomerular filtration rate: the threshold and the equation are important.

    Diabetic Medicine 24(12):1498 (2007) PMID 18042087

  17. Estimated glomerular filtration rate (eGFR) and metformin.

    Diabetic Medicine 24(12):1499; author reply 1499 (2007) PMID 18042089

  18. Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy.

    Diabetic Medicine 24(12):1393 (2007) PMID 17976205

    Glucokinase (GCK)-activating mutations cause persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI). GCK-PHHI patients have regulated insulin secretion and can usually be treated with diazoxide. The six reported cases suggest that the severity of the mutation predicts the clinical phenotyp...
  19. Efficacy of continuous subcutaneous insulin infusion in Type 1 diabetes: a 2-year perspective using the established criteria for funding from a National Health Service.

    Diabetic Medicine 24(12):1419 (2007) PMID 17941861

    To determine the 2-year efficacy of continuous subcutaneous insulin infusion (CSII) following the current established criteria for funding of a National Health Service. Longitudinal, prospective, observational unicentre study. Included in the study were 153 Type 1 diabetes (T1D) subjects, previo...
  20. Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS).

    Diabetic Medicine 24(12):1313 (2007) PMID 17894827

    Patients with Type 2 diabetes have an elevated risk of stroke. The role of lipid levels and diabetes-specific factors in risk prediction of stroke is unclear, and estimates of efficacy of lipid-lowering therapy vary between trials. We examined predictors of stroke and the effect of atorvastatin ...