Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk
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[Dynamics of initial manifestations of experimental diabetic encephalopathy].
We established that alloxan diabetes leads to early development of diabetic encephalopathy on the background of marked hyperglycemia. Initial manifestations of experimental diabetic encephalopathy are based on fast progressing loss of neurons and glial cells in the structures of primary somatosensor...
[Effects of stress factors on adult hippocampus: molecular, cellular mechanisms and dorso-ventral gradient].
Adult hippocampus is one of the brain structures selectively vulnerable to stress factors. In the hippocampus, stress-induced neuroinflammation, neurodegeneration, epileptic activity and disturbances of neurogenesis take place. Stress of different modality specifically affects hippocampal structural...
[Effect of D1/D2 dopamine receptors agonists and antagonists on rats with different choice of reinforcement value].
We noted a trend to change the preferences in choosing pedals for reinforcements, which was different in the rats of two groups--the self-control rats showed a decrease of pressing the pedal to get valuable delayed reinforcements, while in impulsive animals, on the contrary, the number of elections...
[Human cognitive space: coincidence of the models, built on base of EEG rhythms and psychometric measurements].
We could see that these distances formed the arranged space where the spatial, imaginative and verbal thinking types found their logical position along the appropriate coordinate axes forming the model of cognitive space. Furthermore, though the EEG spectra varied across subjects, the distances betw...
[Dynamics of heart rate changes in rats following stepwise change of treadmill running speed].
Amplitude and temporal responses of heart rate to stepwise increase or decrease of treadmill running intensity were investigated in rats. Heart rate amplitude response was shown to be connected mainly with the change of sympathetic nervous activity whereas heart rate temporal response was shown to b...
[Magnetic resonance spectroscopy of metabolic changes in mice brain after 2-deoxy-D-glucose injection].
In vivo proton magnetic resonance spectroscopy (1H MRS) of ICR male mice was used to study the brain (hippocampus) metabolic response to the acute deficiency of the available energy or to the pro-inflammatory stimulus. Inhibition of glycolysis by means of an intraperitoneal injection with 2-deoxy-D-...
[Opioid peptides effect on lipid peroxidation in long-term stress].
It was shown in rats, that injection of opioid peptides (dynorphin A (1-13), DSLET and DAGO) decreased the stress-induced activation of lipid peroxidation in liver tissue and plasma. Dynorphin A (1-13) manifested the most expressed antioxidant effect in liver tissue. It not only decreased lipid perox...
[Cellular factors of ischemia/reperfusion injury pathogenesis in the renal transplantation].
A review of literature reveales the current conception of Russian and foreign authors on the cellular and humoral pathogenetic mechanisms of ischemic and reperfusion injury of kidney transplant.
[Gram-negative bacteria influence on the ability of the arginine-vasotocin to stimulate osmotic permeability of the frog urinary bladder epi...
The influence of endogenous gram-negative bacteria colonizing the mucosal epithelium of frog Rana temporaria L. urinary bladders (FUB) on arginine-vasotocin AVT-stimulated osmotic water flow in isolated urinary bladders was investigated. 170 animals were examined and only 40% were co...
[Transgenerational consequences of acute antenatal stress in pregnant rats].
The aim of the present study was to investigate the effects of acute hypobaric hypoxia in early organogenesis on three following generations including pregnant females (FO) and two generations of their posterity (F1 and F2). Animals of all generations mentioned above demonstrated mar...