Pediatric Infectious Disease Journal
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Five years of kawasaki disease in the Netherlands: a national surveillance study.
The aim of this study was to evaluate the incidence, disease presentation, treatment and cardiac outcome of Kawasaki disease (KD) in The Netherlands. The national Dutch Pediatric Surveillance Unit was used to prospectively register new KD cases from 2008 through 2012. Questionnaires were sent to ped...
Factors affecting time to death from start of treatment among children succumbing to bacterial meningitis.
We compared time to death after initiation of antimicrobial treatment among 206 children with etiology and other patient characteristics. The risks of dying very quickly (0-4 hours), quickly (4-8 hours) or after longer periods were analyzed by logistic regression. Median time to death was 18.5 hours...
Human Herpesvirus 8 Disease: (Last updated November 6, 2013; last reviewed November 6, 2013).
Mycobacterium tuberculosis: (Last updated November 6, 2013; last reviewed November 6, 2013).
Impact of 4.0% chlorhexidine cord cleansing on the bacteriologic profile of the newborn umbilical stump in rural Sylhet District, Bangladesh...
: Randomized trials from South Asia indicate umbilical cord chlorhexidine cleansing reduces mortality and omphalitis. No community-based data are available on bacteriological profile of the cord, early neonatal colonization dynamics, or impact of cord cleansing on colonizing organism...
Evaluation of haemophilus influenzae type b vaccine for routine immunization in Nepali infants.
We determined the immunogenicity of HibCV in Nepali infants, before its introduction into the routine immunization schedule. : Ninety infants recruited at Patan Hospital, Kathmandu, received 3 doses of the HibCV with routine immunizations (diphtheria, tetanus, whole cell pertussis-he...
Antibiotic susceptibility of Kingella kingae isolates from children with skeletal system infections.
Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children.
: The use of the 1:40 HI adult correlate of protection is not appropriate when evaluating influenza vaccines in children. Although a cutoff of 1:110 may be used to predict the conventional 50% clinical protection rate, a titer of 1:330 would predict an 80% protective level, which would seem to be mor...
Genetic differences between invasive and noninvasive neonatal group B streptococcal isolates.
: Our results illustrate a large molecular diversity among neonatal noninvasive GBS strains. Invasive strains, however, represent only a small proportion of the noninvasive GBS population. These findings suggest a selection process that prefers more virulent strains during invasion....
Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005.
: Pneumococcal meningitis is associated with a high case-fatality ratio among South African children and this is increased by HIV coinfection. Increasing access to antiretroviral therapy and a catch-up program for pneumococcal conjugate vaccine among HIV-infected and malnourished children could reduc...