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Antineoplastic effects of Chlorella pyrenoidosa in the breast cancer model.
There has been considerable interest in both clinical and preclinical research about the role of phytochemicals in the reduction of risk for cancer in humans. The aim of this study was to determine the antineoplastic effects of Chlorella pyrenoidosa in experimental breast cancer in vivo and in vitro...
Milk basic protein supplementation enhances fracture healing in mice.
There is an unmet need for agents that can stimulate bone healing. The goal of this study was to evaluate the effects of basic proteins from milk whey (milk basic protein [MBP]) on fracture healing in mice. Closed tibial transverse fractures were generated in 6-wk-old male C3 H/HeJ mice given either...
Sarcopenia impairs prognosis of patients with liver cirrhosis.
We also analyzed the effect of branched-chain amino acid (BCAA) supplementation on sarcopenic LC. Clinical and blood biochemical data of 130 patients with LC who underwent abdominal computed tomography scan were analyzed in this retrospective study. The cross-sectional area of skeletal muscles was m...
Surprising results of a supportive integrated therapy in myelofibrosis.
We reported on a case of a patient with MF who presented with weight loss and cachexia associated with severe anemia, fatigue, fever, and bone pain. The circulating levels of inflammatory, oxidative stress parameters, hepcidin, and erythropoietin were evaluated and were above normal ranges. The pati...
Role of metabolic syndrome and antiretroviral therapy in adiponectin levels and oxidative stress in HIV-1 infected patients.
We allocated 285 patients into four groups: group 1: patients without MetS who were not using ART; group 2: patients without MetS using ART; group 3: patients with MetS who were not using ART; and group 4: patients with MetS using ART. Biochemical, immunologic, and oxidative stress parameters were m...
Management of patients during hunger strike and refeeding phase.
Our data suggested that seriousness and rate of medical complications during the refeeding phase can be kept at a minimum in a hunger strike population. This study supported use of recommendations to optimize risk management and to improve treatment quality and patient safety in this vulnerable popu...
Evaluation of immune response, microbiota, and blood markers after probiotic bacteria administration in obese mice induced by a high-fat die...
Obesity is associated with alterations in intestinal microbiota and immunity. The aim of this study was to determine the effect of probiotic Lactobacillus casei CRL 431 administration on intestinal and humoral immune response, clinical parameters, and gut microbiota was evaluated using a high-fat di...
Effects of Artemisia species on de novo lipogenesis in vivo.
Botanical compounds and extracts are widely used as nutritional supplements for the promotion of health or the prevention of disease. An extract of Artemisia dracunculus (PMI 5011) has been shown to improve insulin action, yet the precise mechanism is not known. The aim of this study is to demonstra...
Cotrimoxazole-induced hypoglycemia in outpatient setting.
Nutritional intakes of patients at risk of pressure ulcers in the clinical setting.
Malnutrition is a risk factor for pressure ulcers. The aim of this study was to describe the energy and protein intakes of hospitalized patients at risk for pressure ulcers and to identify predictors of eating inadequately. An observational study was conducted in four wards at two hospitals in Queen...