Journal of Biomaterials Science, Polymer Edition Â¶
- Print ISSN
- Electronic ISSN
- Impact factor
- Usage rank
- Article count
- Free count
- Free percentage
- PDFs via platforms
- Rcgp, Brill, Ingenta, CSA, and Proquest
Magnetic Drug Targeting as New Therapeutic Option for the Treatment of Biomaterial Infections.
We present a novel strategy to concentrate high antibiotic doses systemically at the target site using newly developed antibiotic-functionalized nanoparticles directed by a magnetic drug-targeting system. The important and effective antibiotic gentamicin served as antimicrobial substance and was ion...
Preparation of PLGA Scaffolds with Graded Pores by Using a Gelatin-Microsphere Template as Porogen.
We assumed that it was probably because of the hydrophobicity and the short culture time. It was demonstrated that gradient ethanol/water solutions provided a simple way to prepared gelatin microspheres. The graded scaffolds would provide potential application for osteochondral regeneration....
Proliferation of Rat Mesenchymal Stem Cells in Collagen Sponges Reinforced with Poly(Ethylene Terephthalate) Fibers by Stirring Culture Meth...
The objective of this study is to investigate the effect of medium stirring conditions on the proliferation of rat mesenchymal stem cells (MSC) in collagen sponges reinforced by the incorporation of poly(ethylene terephthalate) (PET) fibers. A collagen solution with PET fibers homoge...
Efficient Bone Regeneration Induced by Bone Morphogenetic Protein-2 Released from Apatite-Coated Collagen Scaffolds.
We hypothesized that an apatite coating on a type-I collagen scaffold would prolong the BMP-2 release period and enhance bone regeneration in calvarial defects in mice. Apatite coating was achieved by incubating collagen scaffolds in simulated body fluid. BMP-2 release kinetics and bioactivity were...
The Evaluation of Hydroxyl Ions as a Nucleating Agent for Apatite on Electrospun Non-Woven Poly(ɛ-Caprolactone) Fabric.
These results were explained in terms of the degree of apatite supersaturation in SBF induced by the release of hydroxyl ions from the coated NaOH because hydroxyl ions are one of the constituent elements of apatite. These results suggest that hydroxyl ions have a good potential for use as a nucleat...
Transport of phospholipid in silicone hydrogel contact lenses.
Characterization of the transport and release of phospholipids from a silicone hydrogel contact lens is required to assess the possible use of these lenses for phospholipid delivery to increase patient comfort. Contact lenses of silicone hydrogel composition were loaded with varying...
Microfabrication of a three-dimensional polycaprolactone thin-film scaffold for retinal progenitor cell encapsulation.
Retinal degenerations are the leading cause of irreversible visual disability among the adult population. Stem-cell-based therapy has the potential to preserve and restore vision in these conditions. In addition to replacing lost or diseased cells, transplanted cells may be able to rescue dying phot...
Neural progenitor cells survival and neuronal differentiation in peptide-based hydrogels.
We designed nanofibrous hydrogels as 2-D and 3-D scaffolds for anchorage-dependent cells. The IKVAV-containing peptide amphiphile molecules spontaneously self-assembled into higher-order nanofiber hydrogels under cell-containing media. Neural progenitor cells (NPCs) were incubated in peptide-based h...
Effects of chitosan-coated fibers as a scaffold for three-dimensional cultures of rabbit fibroblasts for ligament tissue engineering.
We fabricated chitosan-coated poly(lactic acid) (PLA) fiber scaffolds to test our hypothesis that PLA fibers coated with chitosan highly promoted cell supporting properties compared to those without chitosan. Both PLA fibers (PLA group) and chitosan-coated PLA fibers (PLA-chitosan group) were fabric...
The effect of aligned core-shell nanofibres delivering NGF on the promotion of sciatic nerve regeneration.
We incorporated nerve growth factor (NGF) into aligned core-shell nanofibres by coaxial electrospinning, and reeled the scaffold into aligned fibrous nerve guidance conduits (NGCs) for nerve regeneration study. This aligned PLGA/NGF NGC combined physical guidance cues and biomolecular signals to clo...