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Emerging and re-emerging viruses of the honey bee (Apis mellifera L.).
Until the late 1980s, specific viral infections of the honey bee were generally considered harmless in all countries. Then, with the worldwide introduction of the ectoparasite mite Varroa destructor, beekeepers encountered increasing difficulties in maintaining their colonies. Epidemiological survey...
Rosette nanotubes inhibit bovine neutrophil chemotaxis.
We used biologically-inspired RGD-tagged rosette nanotubes (RNT) to inhibit neutrophil chemotaxis. We hypothesize that RGD-RNT will block neutrophil migration through inhibition of MAPK. In this report, RNT conjugated to lysine (K-RNT) and arginine-glycine-aspartic acid-serine-lysine (RGDSK-RNT) wer...
Management interventions in dairy herds: exploring within herd uncertainty using an integrated Bayesian model.
Knowledge of the efficacy of an intervention for disease control on an individual farm is essential to make good decisions on preventive healthcare, but the uncertainty in outcome associated with undertaking a specific control strategy has rarely been considered in veterinary medicine. The purpose o...
Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs.
We studied gene expression changes in peripheral lymphoid tissues as compared to hepatic expression changes, 14-18 h after lung infection in pigs. The lung infection was established with the pig specific respiratory pathogen Actinobacillus pleuropneumoniae. Quantitative real-time PCR based expressio...
Potential associations between fecal shedding of Salmonella in feedlot cattle treated for apparent respiratory disease and subsequent advers...
A prospective cohort study was used to assess whether Salmonella fecal shedding in commercial feedlot cattle treated with antimicrobials for respiratory disease was associated with subsequent adverse health outcomes. Feces were collected per rectum from cattle that were examined for apparent respira...
Interactions of Haemophilus parasuis and its LOS with porcine brain microvascular endothelial cells.
We recently showed that H. parasuis adheres to and invades porcine brain microvascular endothelial cells (PBMEC). The aim of this study was to evaluate the role of H. parasuis lipooligosaccharide (LOS) in the adhesion to PBMEC and to determine if H. parasuis (and/or its LOS) is able to induce apopto...
Prion agent diversity and species barrier.
We discuss the possible situations resulting from the confrontation between species barrier and prion strain diversity, the molecular mechanisms involved and the potential of interspecies transmission of animal prions, including recently discovered forms of TSE in ruminants....
A homolog of the O157 urease-encoding O island 48 is present in porcine O149:H10 enterotoxigenic Escherichia coli.
The relationship of the urease operon in the highly virulent O149 porcine enterotoxigenic Escherichia coli (ETEC) strain Ro8 to a genomic island (GI) homologous to O island (OI) 48 of O157 enterohemorrhagic E. coli (EHEC) strain EDL933 was investigated. Eighty-four of 84 O149:H10 strains were urease...
Intradermal DNA vaccination in ear pinnae is an efficient route to protect cats against rabies virus.
A DNA vaccine against rabies (pGQH) was administrated to cats in order to examine different administration routes. Four groups of three cats each were inoculated with pGQH as follows: group A, intramuscularly (IM), 100 microg; group B, intranasally (IN), 100 microg; group C, intradermally into ear p...
Effect of genetic resistance of the hen to Salmonella carrier-state on incidence of bacterial contamination: synergy with vaccination.
We derived mathematical models for Salmonella transmission and used them to appreciate the most important factors of variation of egg contamination rate and thus of risk of human contamination. Thanks to recent data of a selection experiment for increased or decreased rate of carrier-state (also cal...