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Veterinary Research

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  1. Correction: Impact of genotype 1 and 2 of porcine reproductive and respiratory syndrome viruses on interferon-α responses by plasmacytoid dendritic cells

    Veterinary Research 44(1):74 (2013) PMCID PMC3848481

  2. Cytopathic bovine viral diarrhea viruses (BVDV): emerging pestiviruses doomed to extinction.

    Veterinary Research 41(6):44 (2010) PMID 20197026

    Bovine viral diarrhea virus (BVDV), a Flaviviridae pestivirus, is arguably one of the most widespread cattle pathogens worldwide. Each of its two genotypes has two biotypes, non-cytopathic (ncp) and cytopathic (cp). Only the ncp biotype of BVDV may establish persistent infection in the fetus whe...
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  3. Pathogenesis of natural goat scrapie: modulation by host PRNP genotype and effect of co-existent conditions.

    Veterinary Research 41(4):48 (2010) PMID 20374697

    After detection of a high prevalence of scrapie in a large dairy goat herd, 72 infected animals were examined by immunohistochemistry with prion protein (PrP) antibody Bar224 to study the pathogenesis of the infection. Tissues examined included the brain and thoracic spinal cord (TSC), a wide se...
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  4. Identification of full length bovine TLR1 and functional characterization of lipopeptide recognition by bovine TLR2/1 heterodimer.

    Veterinary Research 41(3):34 (2010) PMID 20167196 PMCID PMC2831532

    Toll-like receptors (TLR) are highly conserved pattern recognition receptors of the innate immune system. Toll-like receptor 2 (TLR2) recognizes bacterial lipopeptides in a heterodimeric complex with TLR6 or TLR1, thereby discriminating between di- or triacylated lipopeptides, respectively. Prev...
  5. Feeding-associated gene expression in sheep scab mites (Psoroptes ovis).

    Veterinary Research 41(2):16 (2010) PMID 19852923 PMCID PMC2789330

    The mite Psoroptes ovis is the causative agent of sheep scab. Although not usually fatal, the disease can spread rapidly and is a serious animal welfare concern. Vaccine development against ectoparasites has primarily focussed on two sources of candidate vaccine antigens - "exposed" antigens tha...
  6. Effects of growth conditions on biofilm formation by Actinobacillus pleuropneumoniae.

    Veterinary Research 41(1):3 (2010) PMID 19737507 PMCID PMC2762130

    Biofilm formation is an important virulence trait of many bacterial pathogens. It has been reported in the literature that only two of the reference strains of the swine pathogen Actinobacillus pleuropneumoniae, representing serotypes 5b and 11, were able to form biofilm in vitro. In this study,...
  7. Enteric bacterial pathogen detection in southern sea otters (Enhydra lutris nereis) is associated with coastal urbanization and freshwater runoff.

    Veterinary Research 41(1):1 (2010) PMID 19720009 PMCID PMC2769548

    Although protected for nearly a century, California's sea otters have been slow to recover, in part due to exposure to fecally-associated protozoal pathogens like Toxoplasma gondii and Sarcocystis neurona. However, potential impacts from exposure to fecal bacteria have not been systematically ex...
  8. The infection of primary avian tracheal epithelial cells with infectious bronchitis virus.

    Veterinary Research 41(1):6 (2010) PMID 19793537 PMCID PMC2769550

    Here we introduce a culture system for the isolation, passaging and amplification of avian tracheal epithelial (ATE) cells. The ATE medium, which contains chicken embryo extract and fetal bovine serum, supports the growth of ciliated cells, goblet cells and basal cells from chicken tracheas on f...
  9. Characterization of pentraxin 3 in the horse and its expression in airways.

    Veterinary Research 41(2):18 (2010) PMID 19863902 PMCID PMC2789332

    The long pentraxin 3 (PTX3) plays an important role in host defence and its over-expression may contribute to airway injury. The aim of the present study was therefore to characterize in more detail PTX3 and its expression in the horses' airway. Six healthy horses and six horses affected by recu...
  10. Experimental inoculation study indicates swine as a potential host for Hendra virus.

    Veterinary Research 41(3):33 (2010) PMID 20167195 PMCID PMC2826093

    Hendra virus (HeV) is a zoonotic virus from the family Paramyxoviridae causing fatal disease in humans and horses. Five-week-old Landrace pigs and 5-month-old Gottingen minipigs were inoculated with approximately 10(7) plaque forming units per animal. In addition to fever and depression exhibite...