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Matrix Biology

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  1. Announcement - MBE Meeting.

    Matrix Biology 33:77 (2014) PMID 24559888

  2. Pathophysiology of the microfibril/elastic fiber system: introduction

    Matrix Biology 19(6):455 (2000)

  3. Makin' sense of the antisense: HA expression and synthesis requires HAS2-AS1 and O-GlcNAcylation.

    Matrix Biology 41:1 (2015) PMID 25645084

  4. Post-translational modifications of integrin ligands as pathogenic mechanisms in disease.

    Matrix Biology 40:5 (2014) PMID 25116951

    Protein post-translational modifications like glycation, carbamylation and citrullination increase the functional diversity of the proteome but in disease situations might do more harm than good. Post-translational modifications of ECM proteins are thus appearing as mechanisms, which contribute to t...
  5. A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to perip...

    Matrix Biology 38:59 (2014) PMID 25019467 PMCID PMC4199143

    This study investigated changes in collagen fibril architecture and the sulphation status of keratan sulphate (KS) glycosaminoglycan (GAG) epitopes from central to peripheral corneal regions. Freshly excised adult bovine corneal tissue was examined as a function of radial position from the centre of...
  6. Matricellular proteins and biomaterials.

    Matrix Biology 37:183 (2014) PMID 24657843 PMCID PMC4167162

    Biomaterials are essential to modern medicine as components of reconstructive implants, implantable sensors, and vehicles for localized drug delivery. Advances in biomaterials have led to progression from simply making implants that are nontoxic to making implants that are specifically designed to e...
  7. Heparin-dependent regulation of fibronectin matrix conformation.

    Matrix Biology 34:124 (2014) PMID 24148804 PMCID PMC3992196

    We describe a simple antibody-based method for evaluating the conformation of the heparin 2 binding domain in Fn, and use it to determine the relative contributions of heparin and mechanical strain to the regulation of Fn conformation. We achieved specificity in quantifying conformational changes in...
  8. Society for Glycobiology Meeting - 2013
    Author(s) unavailable

    Matrix Biology 32(6):364 (2013)

  9. Inhibition of integrins αv/α5-dependent functions in melanoma cells by an ECD-disintegrin acurhagin-C.

    Matrix Biology 32(3-4):152 (2013) PMID 23333557

    We further evaluate its potential applications in cancer therapy. In vitro assays indicated that acurhagin-C not only may influence the cell viability at higher concentration, but also can potently and dose-dependently decrease cell proliferation in murine B16-F10 melanoma. Otherwise, it also had a...
  10. Nephronectin binds to heparan sulfate proteoglycans via its MAM domain.

    Matrix Biology 32(3-4):188 (2013) PMID 23357641

    We examined the binding of nephronectin to a panel of glycosaminoglycan (GAG) chains. Nephronectin bound strongly to heparin and chondroitin sulfate (CS)-E and moderately to heparan sulfate (HS), but failed to bind to CS-A, CS-C, CS-D, dermatan sulfate and hyaluronic acid. Deletion of the MAM domain...