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Matrix Biology

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  1. Post-translational modifications of integrin ligands as pathogenic mechanisms in disease

    Matrix Biology 40:5 (2014) PMID 25116951

    Protein post-translational modifications like glycation, carbamylation and citrullination increase the functional diversity of the proteome but in disease situations might do more harm than good. Post-translational modifications of ECM proteins are thus appearing as mechanisms, which c...
  2. Announcement – FEBS Advanced Lecture Course
    Author(s) unavailable

    Matrix Biology 40:73 (2014)

  3. Matrix Biology Highlights

    Matrix Biology 38:1 (2014)

  4. MBI-meeting-flyer
    Author(s) unavailable

    Matrix Biology 38:101 (2014)

  5. Matrix Biology Highlights

    Matrix Biology 36:1 (2014)

  6. Structural characterization and biological properties of the amyloidogenic elastin-like peptide (VGGVG)3

    Matrix Biology 36:15 (2014) PMID 24686253

    The peculiar and unique properties of elastin are due to the abundance of hydrophobic residues and of repetitive sequences as XGGZG (X, Z=V, L or A). Unexpectedly, these sequences not only provide elasticity to the whole protein, but are also able to form amyloid-like fibrils. Even tho...
  7. Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins

    Matrix Biology 36:5 (2014) PMID 24681327

    α4-Laminins, such as laminins 411 and 421, are mesenchymal laminins expressed by vascular and lymphatic endothelial cells, leukocytes and other normal cell types. These laminins are recognized by α6β1 and α6β4 integrins and MCAM (CD146), and promote adhesion and migration of the cells....
  8. Matrix Biologists in Action

    Matrix Biology 36:3 (2014)

  9. The hinge region of type VII collagen is intrinsically disordered

    Matrix Biology 36:77 (2014) PMID 24810542

    Type VII collagen (Col7) is important for skin integrity. As a major component of the anchoring fibrils, Col7 is essential for linking different skin layers together. The central collagenous domain of Col7 contains several interruptions of the collagen triple helix. The longest interru...
  10. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Matrix Biology 35:112 (2014) PMID 24509440

    Smooth muscle cell proliferation can be inhibited by heparan sulfate proteoglycans whereas the removal or digestion of heparan sulfate from perlecan promotes their proliferation. In this study we characterized the glycosaminoglycan side chains of perlecan isolated from either primary h...