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Oncogene

Print ISSN
0950-9232
Electronic ISSN
1476-5594
Impact factor
7.414
Publisher
nature
URL
http://www.nature.com/onc/
Usage rank
98
Article count
15971
Free count
8085
Free percentage
0.50623
PDFs via platforms
CSA, Gale, Proquest, Nature, and Ovid from 2003

  1. OTX1 expression in breast cancer is regulated by p53.

    Oncogene 30(27):3104 (2011) PMID 21734711

  2. Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2.

    Oncogene 30(42):4373 (2011) PMID 22011758

  3. Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation.

    Oncogene 30(15):1850 (2011) PMID 21490605

  4. LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.

    Oncogene 34(1):73 (2015) PMID 24336325

    We investigated various components of the NF2-Hippo pathway, and eventually found that MM cells frequently showed downregulation of LIM-domain protein AJUBA, a binding partner of large tumor suppressor type 2 (LATS2), which is one of the last-step kinases of the NF2-Hippo pathway. Although loss of A...
  5. SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.

    Oncogene 33(38):4697 (2014) PMID 24681955 PMCID PMC4180644

    We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of melanoma-initiating cells (MICs). Recent reports indicate that HH-GLI signaling regulates a set of genes typically expressed in embryonic stem cells, including S...
  6. BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling.

    Oncogene 33(11):1418 (2014) PMID 23524581 PMCID PMC3865028

    We created a stable B1 knockdown A549 cell line (B1-KD) to investigate B1's role in microtubule biology and response to taxane treatment. We show that B1-KD rendered A549 cells resistant to paclitaxel (PTX), phenocopying clinical studies showing that low B1 expression correlated with taxane resistan...
  7. RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells.

    Oncogene 33(11):1458 (2014) PMID 23542169

    RUNX3 is silenced by histone modification and hypoxia-inducible factor (HIF)-1α is stabilized under hypoxia, but little is known of cross-talk between RUNX3 and HIF-1α under hypoxia. In the present study, the authors investigated the effect of RUNX3 on HIF-1α stability in gastric cancer cells. RUNX3...
  8. Role of OGR1 in myeloid-derived cells in prostate cancer.

    Oncogene 33(2):157 (2014) PMID 23222714

    We demonstrated that OGR1 deficiency in host cells significantly reduced tumorigenesis of PCa in mice. Adoptive transfer of WT CD11b(+) Gr1(+) double positive (DP) cells, but not T cells, was sufficient to allow tumor development in ogr1(-/-) mice. The expression of an M1 macrophage marker, inducibl...
  9. Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility.

    Oncogene 33(2):193 (2014) PMID 23246964

    We aimed to investigate whether SNPs in the miR-27a gene affect miR-27a expression and alter susceptibility to gastric cancer. Therefore, we conducted a case-control population study and the allele and genotype frequencies for polymorphism rs11671784 in miR-27a gene were examined in the study popula...
  10. MicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate c...

    Oncogene 32(35):4139 (2013) PMID 22986525 PMCID PMC3530025

    We report that miRNAs encoded by miR-106b-25 are upregulated in both primary tumors and distant metastasis. Moreover, increased tumor miR-106b expression was associated with disease recurrence and the combination of high miR-106b and low CASP7 (caspase-7) expressions in primary tumors was an indepen...