Science in China Series C (Life Sciences)
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Characterization of SoxB2 and SoxC genes in amphioxus (Branchiostoma belcheri): implications for their evolutionary conservation.
We isolated two Sox genes: SoxB2 and SoxC from amphioxus (Branchiostoma belcheri), the closest living invertebrate relative of the vertebrates. Alignments of SoxB2 and SoxC protein sequences and their vertebrate homologs show high conservation of their HMG domains. Phylogenic analysis shows that amp...
Regulation of mammalian pre-mRNA splicing
Hyaluronic acid fragments evoke Kupffer cells via TLR4 signaling pathway.
QTL molecular marker location of powdery mildew resistance in cucumber (Cucumis sativus L.).
The cucumber lines, S94 (Northern China open-field type, powdery mildew (PM) susceptible) and S06 (European greenhouse type, PM resistant), and their F(6:7) populations were used to investigate PM resistance under seedling spray inoculation in 2005/Autumn and 2006/Spring. QTL analysis was undertaken...
The effects of the false vocal fold gaps on intralaryngeal pressure distributions and their effects on phonation.
These results may be incorporated in the phonatory models (physical or computational) for better understanding of vocal mechanics. The results might also be helpful in exploring the surgical and rehabilitative intervention of related voice problems....
Efficient generation of transgenic chickens using the spermatogonial stem cells in vivo and ex vivo transfection.
Our data therefore suggest TMGT and TTSSCs are the feasible methods for the generation of transgenic chickens....
Recent progress on the structure of Ser/Thr protein phosphatases.
PP1, PP2A and PP2B, belonging to the PPP family of Ser/Thr protein phosphatases, participate in regulating many important physiological processes, such as cell cycle control, regulation of cell growth and division regulation, etc. The sequence homology between them is relatively high, and tertiary s...
Analysis of genetic diversity and phylogenetic relationships among red jungle fowls and Chinese domestic fowls.
Genetic diversity and phylogenetic relationships among 568 individuals of two red jungle fowl subspecies (Gallus gallus spadiceus in China and Gallus gallus gallus in Thailand) and 14 Chinese domestic chicken breeds were evaluated with 29 microstaellite loci, the genetic variability within populatio...
Construction of infectious cDNA clones of PRRSV: separation of coding regions for nonstructural and structural proteins.
We developed an infectious cDNA clone of an attenuated strain of Type II PRRSV, and further manipulated the infectious cDNA clone by inserting polylinker between ORF1 and ORF2, encoding for nonstructural-or structural-protein, respectively. The cDNA was generated from the cell-attenuated virus strai...
Structural parameterization and functional prediction of antigenic polypeptome sequences with biological activity through quantitative seque...
I and II for major histocompatibility antigen (MHC) epitope of human. It will be useful in immune identification and recognition of proteins and genes and in the design and development of subunit vaccines. Several quantitative structure activity relationship (QSAR) models were developed for various...