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Current Opinion in Obstetrics & Gynecology

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  1. Chemotherapy and amenorrhea: risks and treatment options.

    Current Opinion in Obstetrics & Gynecology 20(4):408 (2008) PMID 18660694

    The purpose of this study is to review the impact of chemotherapy on fertility and to update the reader on the current state of fertility preservation techniques. Chemotherapy results in irreversible damage to ovarian follicles and stromal function, and alkylating agents cause the most significa...
  2. Fetal reduction 2008.

    Current Opinion in Obstetrics & Gynecology 20(4):386 (2008) PMID 18660691

    Multifetal pregnancies have skyrocketed over the past two decades as a consequence of infertility treatments. Multifetal pregnancy reduction has lowered the complications considerably. Here, we review the historical and current literature to determine reasonable statistics upon which to counsel ...
  3. Gynaecological laparoscopy: 'see and treat' should be the gold standard.

    Current Opinion in Obstetrics & Gynecology 20(4):325 (2008) PMID 18660682

    Two hundred and fifty thousand gynaecological laparoscopies are performed yearly in the UK, many of them diagnostic. Unless a patient has major endometriosis and needs advanced surgery, the Royal College of Obstetricians and Gynaecologists suggest a 'see and treat' policy. Thus, gynaecologists w...
  4. Premature ovarian failure: predictability of intermittent ovarian function and response to ovulation induction agents.

    Current Opinion in Obstetrics & Gynecology 20(4):416 (2008) PMID 18660695

    To summarize our current knowledge about the predictability of intermittent ovarian function and the response to ovulation induction agents in patients with premature ovarian failure. In addition to clinical, histological or ultrasonographic features, a new biological marker anti-Müllerian hormo...
  5. Insulin-sensitizing agents and reproductive function in polycystic ovary syndrome patients.

    Current Opinion in Obstetrics & Gynecology 20(4):364 (2008) PMID 18660688

    To review the current reproductive advances in insulin-sensitizing agents for treatment of polycystic ovary syndrome patients. To date, among insulin-sensitizing drugs, only metformin should be used to improve reproductive function in well selected polycystic ovary syndrome patients. Preliminary...
  6. Deep dyspareunia: causes, treatments, and results.

    Current Opinion in Obstetrics & Gynecology 20(4):394 (2008) PMID 18660692

    We critically review the causes and treatments of deep dyspareunia. Endometriosis, pelvic congestion syndrome, and interstitial cystitis have been associated with deep dyspareunia. Although medical therapies may improve deep dyspareunia in women with endometriosis, laparoscopic excision of deep ...
  7. Role of laparoscopic hysterectomy in the management of endometrial cancer.

    Current Opinion in Obstetrics & Gynecology 20(4):337 (2008) PMID 18660684

    By the current review we aim to describe different options for laparoscopic hysterectomy in patients with endometrial cancer and discuss the reported risk factors and limitations of laparoscopic hysterectomy in surgical staging of endometrial cancer. Laparoscopic techniques and equipment have ma...
  8. The role of myomectomy in fertility enhancement.

    Current Opinion in Obstetrics & Gynecology 20(4):379 (2008) PMID 18660690

    To review current available literature on the relationship between fibroids and infertility with particular emphasis on the benefits of myomectomy. Pregnancy complications related to the presence of these lesions and to their removal are also addressed. There is a biological plausibility support...
  9. Bioidentical hormone therapy: a panacea that lacks supportive evidence.

    Current Opinion in Obstetrics & Gynecology 20(4):400 (2008) PMID 18660693

    In the practice of 'bioidentical hormone therapy', it is our belief that pharmacists are compounding bioidentical hormone therapy with the best intentions. These pharmacists are, however, ill informed regarding the lack of scientific underpinning associated with the efficacy and safety of the pr...
  10. Poor responder protocols for in-vitro fertilization: options and results.

    Current Opinion in Obstetrics & Gynecology 20(4):374 (2008) PMID 18660689

    To present the options and the results in the management of poor responders in in-vitro fertilization. There is no controlled ovarian hyperstimulation protocol which is best suited for all poor responders. Low dose gonadotropin-releasing hormone agonist regimes appear to be most advantageous. Pr...