Current Opinion in Obstetrics & Gynecology
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Genomic profiling of breast cancers.
We highlight recent studies that employ high-throughput genomic technologies in an effort to elucidate breast cancer biology, discover new therapeutic targets, improve prognostication and stratification, and discuss the implications for precision cancer medicine....
New ways to successfully target tumor vasculature in ovarian cancer.
The aim of this article was to review the recent literature on potential therapeutic strategies for overcoming resistance to antivascular endothelial growth factor drugs in ovarian cancer. Although clinical benefits of antivascular endothelial growth factor therapy were observed in ovarian cancer tr...
Interventions to modify the progression to type 2 diabetes mellitus in women with gestational diabetes: a systematic review of literature.
We undertook a systematic review to assess the effectiveness of interventions that delay or prevent the onset of T2DM in women with previous gestational diabetes. Diet and lifestyle interventions show differing effects on women with GDM and their long-term risk of T2DM. Pharmacological interventions...
The benefits and challenges of robotic-assisted hysterectomy.
To analyze the recent evidence on robotic hysterectomy while highlighting its benefits and challenges. Increased rates of robotic hysterectomy have led to decreasing rates of abdominal hysterectomy, after rates of the latter approach have been stagnant for many years. Robotic surgery has also the po...
A review on the role of laparoscopic sacrocervicopexy.
These results are similar to laparoscopic and abdominal sacrocolpopexy, and are confirmed by the results of two comparative studies. Mesh erosion risk is very low in patients treated with laparoscopic sacrocervicopexy. Studies that compare laparoscopic sacrocolpopexy with concomitant total hysterect...
Diagnosis of abdominal wall defects in the first trimester.
We review recent studies using new parameters to diagnose abdominal wall defects in the first trimester and to provide early prenatal counselling to parents regarding prenatal and postnatal prognosis....
All strategies great and small.
Evidence and opinion: finding the proper balance.