Journal of Law, Medicine & Ethics
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A framework for analyzing the ethics of disclosing genetic research findings.
We go on to propose that, underlying all the seeming confusion and disagreement, three central and widely agreed upon concepts are at work in this debate - validity, value, and volition. Refocusing attention on these core concepts, and their appropriate conceptualizations, can produce a more product...
Using public health legal counsel effectively: beliefs, barriers and opportunities for training.
Our findings are based on two studies: (1) a mixed methods study of state and local public health officials and their legal counsel, including surveys and qualitative interviews; and (2) a survey-based needs assessment of training for public health law. While state health officials and legal counsel...
"Something of an adventure": postwar NIH research ethos and the Guatemala STD experiments.
We focus on the institutional context and research ethos that shaped the outcome of the research. After the end of WWII, Dr. Cassius Van Slyke reconstructed the federal research contracts process into a grant program. The inaugural NIH study section recommended approval of the Guatemala STD experime...
Currents in contemporary bioethics. Access to sensitive information in segmented electronic health records.
Looking for better health in all the wrong places: the road to "equality" hits a dead end.
The actual evidence base for measures of health inequality among the elderly in the United States remains rather thin. Addressing the real causes of health inequalities will require measuring what matters, accounting for the time lags and non-health-care factors behind the development of future heal...
An empirical examination of the current state of publically available nanotechnology guidance materials.
As part of "Nanodiagnostics and Nanotherapeutics: Building Research Ethics and Oversight," an empirical search was conducted to identify publicly available resources that guided understanding about human subjects issues in nanomedicine or nanotechnology including policy statements, guidance document...
What is unique about nanomedicine? The significance of the mesoscale.
Unlike drugs and medical devices, for which long standing and continuously improving quality assurance/quality control infrastructures exist, many nano-based products lack well-defined standards that are useful to manufacturers and regulators. Inherent variabilities in nanoparticle sizes and shapes,...
Beyond human subjects: risk, ethics, and clinical development of nanomedicines.
I describe how similar challenges were encountered and addressed in gene transfer, and sketch policy options that might be explored in the nanomedicine translation arena. © 2012 American Society of Law, Medicine & Ethics, Inc....
Toxic legacy: mustard gas in the sea around us.